Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Biomedical detection system based on nanoimprinted microfluidic chip and manufacturing method thereof

A microfluidic chip and nano-imprint technology, which is applied in the field of biomedical detection, can solve the problems of insufficient miniaturization of sensor chips, and achieve the effects of easy production and promotion, good light transmission, and convenient detection.

Pending Publication Date: 2018-04-20
厦门百恩芯科技有限公司
View PDF0 Cites 9 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, it is not enough to only miniaturize the sensor chip. How to complete large-scale parallel detection on a miniaturized chip is also a problem that needs to be solved.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Biomedical detection system based on nanoimprinted microfluidic chip and manufacturing method thereof
  • Biomedical detection system based on nanoimprinted microfluidic chip and manufacturing method thereof
  • Biomedical detection system based on nanoimprinted microfluidic chip and manufacturing method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0049] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

[0050] In the embodiment of the present invention, the microfluidic chip 5 and the SPR detection chip 10 are bonded, and then the detection chip 13, which is bonded to the SPR sensor chip carrying the sample to be detected and the microfluidic chip, is loaded into the fixture, and illuminated by an LED lamp. The detection chip 13 combined with the SPR sensor chip and the microfluidic chip makes it produce the SPR effect, and transmits the emitted light to the c...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
Thicknessaaaaaaaaaa
Thicknessaaaaaaaaaa
Diameteraaaaaaaaaa
Login to View More

Abstract

The invention discloses a biomedical detection system based on a nanoimprinted microfluidic chip and a manufacturing method thereof. The biomedical detection system comprises the microfluidic chip, anSPR detection chip, a mechanical fixture and a ring-shaped LED light emitting array. The SPR detection chip is mainly obtained by compounding a substrate, a nanoimprinted adhesive, a chromium film and a gold film from bottom to top; a plurality of sets of microfluidic channels fabricated by SU-8 glue lithography and PDMS film-forming method are arranged in the microfluidic chip, and each microfluidic channel mainly comprises an S-shaped microfluidic channel, feeding channels and an outflow channel, wherein the feeding channels and the outflow channel are connected at the two ends of the S-shaped microfluidic channel. The microfluidic technology is adopted in the biomedical detection system, the microchannels are arranged on the nanoimprinted sensor chip to process or manipulate tiny fluids, and rapid multi-channel parallel detection on the small chip can be realized by use of a very small amount of reagent. At the same time, the detection chip is connected with an embedded device to form the detection system by the mechanical fixture, and the automated detection process is very convenient to complete by use of the information processing function of the embedded device.

Description

technical field [0001] The invention relates to the field of biomedical detection, in particular to a biomedical detection system based on nano-imprinted microfluidic chips and a manufacturing method thereof. Background technique [0002] With the development of contemporary science and technology, people have higher and higher requirements for small, fast and parallel detection technology of multiple substances, especially in the field of biomedicine. Smaller and faster detection methods can help people better detect themselves The physical condition can even be tested without leaving home. The sensor based on surface plasmon resonance (Surface Plasmon Resonance, SPR) technology provides a new idea for the miniaturization of the detection chip. SPR is a physical optical phenomenon caused by the interaction between light waves and metal electrons. When the vector component of the light wave propagating along the metal interface is equal to the vector component of the surfac...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): B01L3/00G01N21/55H01L21/18
CPCH01L21/187G01N21/55B01L3/5027B01L2200/10B01L2300/0861B01L2300/12
Inventor 朱锦锋吴秋斌高云之
Owner 厦门百恩芯科技有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products