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Pigmentum for muscle and bone injuries and preparation method of pigmentum

A kind of wound varnish, tendon and bone technology, applied in the medical field, can solve the problems of colloid residue, poor treatment effect of ointment, easy to fall off, etc., achieve the effect of increasing phosphate activity, promoting the disappearance of hematoma, and increasing the extraction rate

Inactive Publication Date: 2018-04-24
黄旭东
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The technical problem to be solved by the present invention: Aiming at the problem that the current plaster is attached to the body, because sweat or other moisture penetrates into the plaster, it is easy to fall off, there will be colloid residue when peeling off, and the existing plaster has poor therapeutic effect. Muscle and bone injury varnish and preparation method thereof

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Penetration enhancer: take notopterygium, add hexane and lithium chloride aqueous solution with a concentration of 0.1mol / L at a mass ratio of 1:10:5, stir and mix for 2 hours, reflux and extract for 2 hours, extract the extract with n-heptane, and extract the extract Nitrogen blowing, rotary evaporation, take the rotary evaporator, add anhydrous sodium sulfate at a mass ratio of 1:5, dry, filter through a 0.22 μm microfiltration membrane, and take the filtrate to obtain a penetration enhancer.

[0027] Analgesic: Take the whole worm of the worm and crush it through a 100-mesh sieve, collect the sieved particles A, add a 70% ethanol solution at a mass ratio of 1:8, extract at 25°C for 2 days, and take the extract at a mass ratio of 1 : 6, add water and mix, adjust the pH to 1, extract twice with ethyl acetate, take the extract by rotary evaporation, adjust the pH to 7, concentrate, and the concentrate is the analgesic.

[0028]Blood-activating and stasis-removing agent:...

Embodiment 2

[0033] Penetration enhancer: take notopterygium, add hexane and lithium chloride aqueous solution with a concentration of 0.1mol / L at a mass ratio of 1:10:5, stir and mix for 3 hours, reflux and extract for 2.5 hours, extract the extract with n-heptane, and extract Liquid nitrogen blowing, rotary evaporation, take the rotary evaporator, add anhydrous sodium sulfate at a mass ratio of 1:5, dry, filter through a 0.22 μm microfiltration membrane, and take the filtrate to obtain a penetration enhancer.

[0034] Analgesic: Take the whole worm of the worm and crush it through a 100-mesh sieve, collect the sieved particles A, add a 70% ethanol solution at a mass ratio of 1:8, extract at 30°C for 3 days, and take the extract at a mass ratio of 1 : 6, add water and mix, adjust the pH to 2, extract 3 times with ethyl acetate, take the extract by rotary evaporation, adjust the pH to 7.2, concentrate, and the concentrate is the analgesic.

[0035] Blood-activating and stasis-removing agen...

Embodiment 3

[0040] Penetration enhancer: take notopterygium, add hexane and lithium chloride aqueous solution with a concentration of 0.1mol / L at a mass ratio of 1:10:5, stir and mix for 2.5 hours, reflux and extract for 2.25 hours, extract the extract with n-heptane, and take The extract liquid was blown with nitrogen, and rotary evaporated, and the rotary evaporated product was added with anhydrous sodium sulfate at a mass ratio of 1:5, dried, filtered through a 0.22 μm microfiltration membrane, and the filtrate was obtained to obtain a penetration enhancer.

[0041] Analgesic: Take the whole worm and crush it through a 100-mesh sieve, collect the sieved particles A, add 70% ethanol solution at a mass ratio of 1:8, extract at 27°C for 2.5 days, and take the extract according to the mass ratio Add water at 1:6 and mix, adjust the pH to 1.5, extract twice with ethyl acetate, take the extract by rotary evaporation, adjust the pH to 7.1, concentrate, and the concentrate is the analgesic.

...

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PUM

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Abstract

The invention discloses pigmentum for muscle and bone injuries and a preparation method of the pigmentum, and belongs to the field of medical treatment. Phaseolin polypeptides are extracted from pearlmussel shells, and by using the micromolecule structure of the phaseolin polypeptides, the phaseolin polypeptides more quickly enter the skin along with a penetration enhancer and a micro-emulsion system and reach an action point; the phaseolin polypeptides are phosphorylated, phosphate radicals are esterified with hydroxide radicals of proteins and amidogen radicals of lysine, and a lot of phosphate radicals are added into protein molecules, so that the nutritive value of the proteins is improved, and the pigmentum has an obvious effect on preventing osteoporosis, increasing the bone mineraldensity and improving the immune function of a bone mechanism. The pigmentum solves the problems that when an existing plaster is stuck to the body, sweat or other water is permeated into ointment, consequently, the plaster is prone to falling off, after the plaster falls off, adhesive residues can remain, and the existing ointment is poor in treatment effect.

Description

technical field [0001] The invention belongs to the medical field, and in particular relates to a tendon and bone injury varnish and a preparation method thereof. Background technique [0002] In traditional Chinese medicine, bone injury is a relatively broad concept, including fractures, joint dislocations, muscle injuries, bone injuries, periosteal injuries and other diseases, as well as bone hyperplasia, frozen shoulder, cervical spondylosis, lumbar disc herniation, rheumatic Arthritis and other diseases, lumbar muscle strain, lumbar degenerative disease (lumbar spine hyperosteogeny), osteoporosis, etc. Lumbago caused by TCM syndromes of kidney deficiency are high-incidence diseases that plague the middle-aged and elderly people in my country. At present, there are few medicines with high curative effect, convenient use and little side effects. For these diseases, Western medicine generally uses oral medicine or supplemented by physical therapy, massage, etc., and its eff...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61K36/889A61P19/08A61K35/618A61K35/63A61K31/167
CPCA61K9/0014A61K31/167A61K35/618A61K35/63A61K36/237A61K36/286A61K36/889A61K36/896A61K47/14A61K2300/00
Inventor 黄旭东郑薇程依
Owner 黄旭东
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