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Eucommia charcoal-containing chewable tablet and preparation method thereof

A chewable tablet and Eucommia charcoal technology, which can be used in pharmaceutical formulations, medical preparations with inactive ingredients, and medical preparations containing active ingredients, etc., can solve problems such as difficulty in taking, achieve good taste, improve bioavailability, and and the effect of dosage form advancement

Inactive Publication Date: 2018-06-01
HEFEI NORMAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] Although Eucommia charcoal has the above effects, it is difficult to take, and there is an urgent need for a chewable tablet of Eucommia charcoal that can be taken

Method used

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  • Eucommia charcoal-containing chewable tablet and preparation method thereof
  • Eucommia charcoal-containing chewable tablet and preparation method thereof
  • Eucommia charcoal-containing chewable tablet and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] A eucommia charcoal chewable tablet, the components it contains and the mass percentage of each component are as follows:

[0040]

[0041]

[0042] The preparation method of Eucommia charcoal chewable tablets in this embodiment is as follows: take the pulverized raw materials, weigh them accurately according to the prescription ratio, mix the materials evenly; add 70% or 60% or 80% ethanol solution for wetting; granulate; dry at low temperature ; Crush; Tablet (pressure 10MPa).

Embodiment 2

[0044] A eucommia charcoal chewable tablet, the components it contains and the mass percentage of each component are as follows:

[0045]

[0046] The preparation method of the eucommia charcoal chewable tablet of the present embodiment is as follows: take the pulverized raw material, accurately weigh it according to the prescription ratio, and mix the material evenly; add 70% ethanol solution for wetting; granulate; dry at low temperature; pulverize; tablet ( Pressure 10MPa).

Embodiment 3

[0048] A eucommia charcoal chewable tablet, the components it contains and the mass percentage of each component are as follows:

[0049]

[0050]

[0051] The preparation method of the eucommia charcoal chewable tablet of the present embodiment is as follows: take the pulverized raw material, accurately weigh it according to the prescription ratio, and mix the material evenly; add 70% ethanol solution for wetting; granulate; dry at low temperature; pulverize; tablet ( Pressure 10MPa).

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PUM

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Abstract

The invention discloses an eucommia charcoal-containing chewable tablet and a preparation method thereof, eucommia charcoal-containing chewable tablet comprises the following components in percent bymass: 56.11-68.48% of eucommia charcoal powder, 10.94-22.23% of microcrystalline cellulose, 5.18-6.49% of pregelatinized starch, 0.62-0.65% of micropowder silica gel, 8.42-9.97% of povidone, 0.66-0.71% of magnesium stearate, 1.37-1.77% of medicinal lactose and 1.88-2.07% of sodium carboxymethyl starch. The eucommia charcoal-containing chewable tablet can not only preserve the medicinal efficacy ofeucommia charcoal, but also improve the mouth feel and reusability, and has an outstanding health-care function.

Description

technical field [0001] The invention relates to an Eucommia charcoal chewable tablet and a preparation method thereof. Background technique [0002] Eucommia charcoal has the following effects: [0003] 1. Antibacterial and anti-inflammatory effects: Eucommia charcoal water extract has inhibitory effects on Mycobacterium tuberculosis, Shigella flexneri, Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, pneumococcus, and Bacillus anthracis. [0004] 2. Anti-tumor effect: Studies have proved that Eucommia charcoal has anti-cancer and anti-cancer effects, and its active ingredients are related to the lignans, phenylpropanoids, and iridoids contained in it. [0005] 3. Antihypertensive effect: Eucommia charcoal has the effect of two-way regulation of blood pressure. It can lower blood pressure for hypertensive patients and increase blood pressure for hypotensive patients. This is unmatched by any chemical antihypertensive drugs, so Eucommia is considered the worl...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61K47/36A61K47/38A61K36/46A61P31/04A61P35/00A61P9/12A61P39/06
CPCA61K9/0056A61K9/2054A61K9/2059A61K36/46
Inventor 郑斌王艳苹朱文娟解燕
Owner HEFEI NORMAL UNIV