A kit for predicting whether children are susceptible to dental caries

Abstract

The invention relates to a kit for predicting dental caries susceptibility of children. The kit contains maltose, alpha-methyl-D-galactoside, alpha-amygdalin, D,L-alpha-phosphoglyceride, D-trehalose,3-methyl-D-glucose, turanose, glycyl-L-tyrosine-L-proline, L-glutamine and glycyl-L-tyrosine-L-glutamine, wherein the components are 10 carbon sources in all for predicting the risk of dental caries of children. The kit can be used in medical institutions or even families, and the illness risk can be predicted before children have dental caries, so that dental caries can be prevented in advance, and society resources for dental caries can be greatly reduced.

Description

technical field [0001] The invention relates to the technical field of stomatology, in particular to the prediction of the risk of dental caries in children. Background technique [0002] Early childhood caries (ECC), formerly known as feeding bottle caries or feeding caries, is considered to be a worldwide problem in pediatrics and public health. This is a chronic disease that occurs in children. It is most prevalent in the age of 2-5, but it is often overlooked by people. Treatment of caries in children is often difficult and costly. Treatment under general anesthesia and a hospital qualified to carry out general anesthesia are needed for the treatment of ECC. [0003] Previous studies have looked at taxonomic bacterial diversity. Although these studies provide us with a lot of important evidence about the relationship between oral microbes and plaque, they limit the depth of our understanding of the ecological association of microbial communities. Most of these studie...

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Problems solved by technology

[0007] However, there are no relevant research reports on the metabolic characteristics of oral microorganisms in ECC patients and healthy individuals, and there are no practical products or methods based on the above research.

Although both caries and periodontitis are plaque-dependent diseases, relying only on the existing detection models of periodontitis and corresponding conclusions cannot help to obtain relevant information on caries. The reasons include: the pathogenicity of periodontitis and caries The pathogenic bacteria are not the same; the pathogenic bacteria of periodontitis and caries are antagonistic to each other, and it is difficult to coexist; periodontitis and caries have different metabolic signature fingerprints for different carbon sources; the processing of the two detection samples will also be different. Compared with healthy people, the time when carbon sources show significant differences or other parameters of related models in the experiment and their optimal values ​​will also be different

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