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38 results about "Phosphoglyceride" patented technology

Phospholipid in which the phosphate group of a phosphatidic acid is joined in ester linkage to an alcohol moiety; major components of cell membranes.

Application of lipid-modified substance of chlorogenic acid and derivative thereof

The invention provides a lipid-modified substance of chlorogenic acid and a derivative thereof, and a preparation and purification method of the lipid-modified substance, wherein the lipid-modified substance includes the chlorogenic acid or the derivative thereof and phosphoglyceride. A preparation process includes steps of performing constant-temperature magnetic stirring reflux for a certain time to the chlorogenic acid or the derivative thereof and the phosphoglyceride with an aprotic solvent and drying an obtained reaction liquid to obtain a crude product. A purification process includes the steps of re-dissolving the crude product with filtration to obtain a filtrate and then drying the filtrate. The lipid-modified substance of the chlorogenic acid and the derivative thereof is high in composition rate and can significantly improve the fat-solubility of the chlorogenic acid and the derivative thereof, so that a subsequent preparation is convenient to process and shape. The lipid-modified substance can be used as an intermediate for preparing a lipidosome, nano particles, polymer micelles or a dendritic polymer and the like nano drug-delivery systems and micro emulsion, self-micro emulsion and the like micron drug-delivery systems, thereby enhancing in-vivo absorption of the chlorogenic acid and the derivative thereof and further increasing the bioavailability of the medicines in a preparation.
Owner:任静 +1

Waterproof anti-crack environment-friendly coating and preparation method thereof

The invention discloses a preparation method of waterproof anti-crack environment-friendly coating. The preparation method comprises the following steps: mixing 35 to 55 parts of attapulgite, 12 to 16 parts of sericite, and 10 to 17 parts of titanium dioxide to obtain a mixture I, putting the mixture I into a grinding machine for grinding, so as to obtain a substance A; adding the substance A, 20 to 30 parts of a styrene-acrylic emulsion and 11 to 18 parts of polyethylene glycol into a stirring device, and carrying out stirring at 60 to 80 DEG C for reaction, so as to obtain a substance B; adding 8 to 15 parts of betulin, 12 to 16 parts of hydroxypropyl methyl cellulose, and 7 to 13 parts of phosphoglyceride into the substance B in sequence under the condition that stirring is carried out continuously, and carrying out a primary reaction at 80 to 100 DEG C; adding 2 to 8 parts of silver oxide, 3 to 7 parts of zinc sulfate, and 2 to 7 parts of carbohydrazide, and carrying out a secondary reaction for 40 to 60 minutes; carrying out cooling and drying to obtain the waterproof anti-crack environment-friendly coating. The waterproof anti-crack environment-friendly coating prepared according to the preparation method not only has application properties of common coating, but also is environment-friendly, generates no pollution to human bodies and the ambient environment, and is excellent in water resistance and anti-crack property, and wide in application prospect.
Owner:SUZHOU FAST INFORMATION TECH CO LTD

Cholinesterase inhibitor preparation method

The invention discloses a cholinesterase inhibitor preparation method, and belongs to the technical field of separation and purification of natural medicines. The preparation method comprises: soakinga macroporous cation exchange resin by using an acid solution, completely removing the acid liquid, rinsing with water, soaking with an alkali liquid, rinsing with water, soaking with an acid liquid,rinsing with deionized water, and replacing with lower alcohol; adding glycerol phosphate to the lower alcohol, adding an alkali, carrying out a reaction, carrying out suction filtration, washing with lower alcohol, adjusting the pH value to a weakly alkaline state, carrying out pressure reducing concentrating, cooling, transferring into a separatory funnel, standing, and separating to obtain a lower layer lower alcohol phase; loading glycerol phosphate and a phenol formaldehyde resin onto a column, loading the alcoholysis mixing liquid onto the column, adsorbing, washing the resin with loweralcohol to remove impurities, and eluting the resin with pure water; and decolorizing with a decolorizing agent, and carrying out pressure reducing concentrating to obtain the finished product. According to the present invention, the process steps are short, the requirements of industrial production are met, the resources are saved, the cost is reduced, the total yield of the finished products is65.47-86.08%, the external standard content is over 99%, and the optical purity is 99%.
Owner:张欣

Novel listeriosis selective separating medium, preparation method and application thereof

The invention relates to the technical flied of biological examination, and especially relates to a novel listeriosis selective separating medium, a preparation method and an application thereof. A formula of the novel listeriosis selective separating medium comprises 4 g of beef brain infusion powder, 4 g of beef heart infusion powder, 5 g of peptone, 16 g of casein peptone, 5 g of sodium chloride, 2 g of sodium pyruvate, 2 g of glucose, 2.5 g of sodium bicarbonate, 1 g of phosphoglyceride, 12. 5 g of agar powder, 5 ml of a phosphatidylinositol solution with concentration being 0.1 g / ml, 5 ml of a pyrans glucoside solution with concentration being 0.02 g / ml, and 5 ml of a propolis solution with concentration being 0.0125-128.0 [mu]g / ml in each liter of distilled water. The method employs natural antibiosis substance propolis as a selective additive of the listeriosis selective separating medium, an improved basic medium is combined for usage, the background microbe growth in various food can be effectively inhibited, so that the growth of the listeriosis in the selective medium is good, the growth of 13 types of serotype bacterial strains of listeriosis is good, and the pathogenic bacteria can be accurately and sensitively detected in the various food.
Owner:HEBEI NORMAL UNIVERSITY OF SCIENCE AND TECHNOLOGY

High-quality, high-efficiency and environment-friendly rabbit skin tanning technology

The invention relates to the technical field of rabbit skin treatment and breeding, and in particular relates to a high-quality, high-efficiency and environment-friendly rabbit skin tanning technologywhich comprises the following steps: S1, skin selection and water immersion: selecting rabbit skin without skin and hair damage and hair removal; S2, preparing a softener: weighing an amino acid typesurfactant, polyether modified hydrophilic silicone oil, phosphoglyceride, a preservative, lauryl sodium sulfate, a mildew preventive and the like in parts by weight in proportion, and blending withwater; S3, softening: soaking the rabbit skin in the S1 in the softener until the rabbit skin is completely soaked in the softener; s4, tanning the rabbit skin: adding a tanning agent and water according to the concentration of 5-15g/L, mixing, and soaking the rabbit skin in the mixture; and S5, drying: fishing out the rabbit skin obtained in the step S4, and putting the rabbit skin on a drying rack for drying treatment until the rabbit skin is completely dried, thereby obtaining a finished rabbit skin product. The rabbit skin prepared by the method is softer and softer, and then the rabbit skin is tanned, so that the tanned rabbit skin is natural in color and luster and lighter in texture.
Owner:中梁农业集团股份有限公司

Preparation technology of DNA (DesoxyriboNucleic Acid) for treating pneumonia

The invention discloses a preparation technology of DNA (DesoxyriboNucleic Acid) for treating pneumonia and belongs to the technical field of separation purification of natural drugs. The preparationtechnology comprises the following steps: soaking macroporous cation exchange resin with acid fluid, completely draining the acid fluid and flushing with water; then soaking with lye and flushing withthe water; then soaking the macroporous cation exchange resin with the acid fluid again, flushing with deionized water and replacing with low carbon alcohol; adding phosphoglyceride into the low carbon alcohol, adding alkali for reacting, carrying out suction filtration, washing with the low carbon alcohol, and adjusting the pH to weak basicity, carrying out vacuum concentration, cooling, transferring to a separating funnel, standing and separating out a lower low carbon alcohol phase; loading the phosphoglyceride and phenolic resin on a column, carrying out column adsorption on alcoholysis mixed liquid, washing the resin with the low carbon alcohol, purifying and eluting the resin with pure water; decolorating by using a decoloring agent and carrying out vacuum concentration to obtain afinished product. The preparation technology has the advantages that technological steps are short and the requirements of industrial production are met; resources are saved and the cost is reduced; the total yield of a finished product reaches 65.47 to 86.08 percent, the external standard content reaches 99 percent or above and the optical purity reaches 99 percent.
Owner:孔祥圣

Preparation method of phosphatidyl glycerol inhibitor

The invention relates to a preparation method of a phosphatidyl glycerol inhibitor, belonging to the technical field of separation and purification of natural medicines. The method comprises the following steps: firstly, soaking macroporous cation exchange resin in an acid solution, draining the acid solution, and rinsing with water; then, soaking in an alkali solution, and rinsing with water; then, soaking in the acid solution, rinsing with deionized water, and then using lower alcohol for replacing; adding glycerol phosphate into the lower alcohol, adding alkali for carrying out a reaction,and then performing suction filtration; washing with the low alcohol, adjusting pH to be weakly alkaline, concentrating under reduced pressure and cooling, then transferring into a separating funnel,standing, and separating out a lower layer lower alcohol phase; packing the glycerol phosphate and phenolic resin in a column, carrying out on-column absorption on alcoholysis mixed liquid, washing the resin with the lower alcohol for removing impurities, and eluting the resin with pure water; carrying out decolorization by using a decolorizing agent, and concentrating under reduced pressure to obtain the finished product. The preparation method has the advantages that the technological steps are simple and short, and the requirements of industrial production are met; the resources are saved,and the cost is lowered; the total yield of the finished product reaches 65.47-86.08%, the external standard content reaches 99% or above, and the optical purity reaches 99%.
Owner:陕西卓力时代人力资源有限公司

Novel glycerol phosphatidylcholine preparation method

The invention discloses a novel glycerol phosphatidylcholine preparation method, and belongs to the technical field of separation and purification of natural medicines. The preparation method comprises: soaking a macroporous cation exchange resin by using an acid solution, completely removing the acid liquid, rinsing with water, soaking with an alkali liquid, rinsing with water, soaking with an acid liquid, rinsing with deionized water, and replacing with lower alcohol; adding glycerol phosphate to the lower alcohol, adding an alkali, carrying out a reaction, carrying out suction filtration, washing with lower alcohol, adjusting the pH value to a weakly alkaline state, carrying out pressure reducing concentrating, cooling, transferring into a separatory funnel, standing, and separating toobtain a lower layer lower alcohol phase; loading glycerol phosphate and a phenol formaldehyde resin onto a column, loading the alcoholysis mixing liquid onto the column, adsorbing, washing the resinwith lower alcohol to remove impurities, and eluting the resin with pure water; and decolorizing with a decolorizing agent, and carrying out pressure reducing concentrating to obtain the finished product. According to the present invention, the process steps are short, the requirements of industrial production are met, the resources are saved, the cost is reduced, the total yield of the finished products is 65.47-86.08%, the external standard content is over 99%, and the optical purity is 99%.
Owner:张欣
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