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Application of radix tetrastigme extract in preparation of febrile convulsion resisting drug

A technology for febrile convulsion and cloverleaf, applied in the field of medicine, can solve problems such as large toxic and side effects, and achieve the effects of prolonging the occurrence time, shortening the duration of convulsions, and reducing the degree of occurrence of convulsions

Inactive Publication Date: 2018-06-22
ZHEJIANG CHINESE MEDICAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] Western medicine mainly includes physical cooling, application of antipyretic analgesics (such as carbasalate calcium, aspirin lysine, ibuprofen, acetaminophen, naphthalene, etc.) to the treatment of diseases such as convulsions and infections caused by high fever. Probiotics and other non-steroidal drugs) and antiviral and antibacterial drugs (such as acyclovir, amantadine, ribavirin, penicillin, etc.), and hormone combination therapy, although its effect is fast, but the side effects are large
At present, there is no relevant literature report on the use of clover leaf extract for febrile convulsion diseases

Method used

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  • Application of radix tetrastigme extract in preparation of febrile convulsion resisting drug
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Embodiment Construction

[0014] The present invention will be further described below in conjunction with the examples. It should be noted that the following descriptions are only for explaining the present invention and not limiting its content.

[0015] The Sanyeqing decoction pieces involved in the present invention are purchased from Zhejiang University of Traditional Chinese Medicine Decoction Pieces Co., Ltd.

[0016] Animal model replication and group processing

[0017] The Kunming mice were adaptively fed at room temperature around 23°C for 5 days, and the rectal temperature was measured once a day in the morning and evening on the 4th and 5th day. The average value of rectal temperature was taken as the basal body temperature, and mice whose body temperature fluctuation range did not exceed 38.0°C and whose body temperature fluctuations did not exceed 0.4°C in the two measurements were selected.

[0018] The mice meeting the requirements were randomly divided into normal group, model group,...

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Abstract

The invention discloses an application of a radix tetrastigme extract in preparation of a febrile convulsion resisting drug. The radix tetrastigme extract is extracted from radix tetrastigme. Animal experiments verify that the radix tetrastigme extract can effectively resist febrile convulsion and induce that the occurrence time of the febrile convulsion is prolonged obviously, the convulsion duration is remarkably shortened and the convulsion degree is notably reduced.

Description

technical field [0001] The invention relates to a new application of medicine, in particular to the application of trifoliate green extract in the preparation of anti-febrile convulsion medicine. It belongs to the field of medical technology. Background technique [0002] Febrile convulsions are common convulsive diseases in children, which refer to convulsions induced by pure fever. Febrile convulsions mostly occur in the early stage of upper respiratory tract infection. When the body temperature rises sharply to 38.5-40°C or higher, convulsions suddenly occur. Children with convulsions have a sudden onset. If they do not receive timely treatment, prolonged convulsions or multiple recurrences can damage brain cells and affect mental development. Febrile convulsions are more common in children aged 1 to 3, with an incidence rate of 40 to 60%. The pathogenesis of febrile seizures is complex, and its pathogenesis and treatment methods have been studied clinically. [0003]...

Claims

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Application Information

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IPC IPC(8): A61K36/87A61P29/00A61P25/08A61K125/00
CPCA61K36/87A61K2236/333A61K2236/39A61K2236/51A61K2236/55
Inventor 曹岗张纪达
Owner ZHEJIANG CHINESE MEDICAL UNIVERSITY