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False tooth cleaning agent and preparation method thereof

A denture cleaner and tooth cleaning technology, which is applied in dentistry, pharmaceutical formulations, cosmetic preparations, etc., can solve the problems of denture cleaners such as poor ability to remove dirt and sterilize, slow down the deposition rate, and inhibit the water-insoluble glucosamine. Production of glycans, effect of weakening adhesion

Inactive Publication Date: 2018-08-24
CHANGZHOU AMANTE CHEM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The technical problem to be solved by the present invention is to provide a denture cleanser and its preparation method in view of the poor dirt removal ability and sterilizing ability of the current denture cleanser

Method used

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  • False tooth cleaning agent and preparation method thereof

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preparation example Construction

[0031] A preparation method of a denture cleaner, comprising the steps of:

[0032] a. Take chitosan and add methanesulfonic acid at a mass ratio of 1:20, stir and mix at 40~50°C for 1~2h, pass through nitrogen protection, and then add hexadecyl chloride 2~4 times the mass of chitosan, Stir and mix at 25~30°C for 4~5h to obtain a stirred mixture, take the stirred mixture and add distilled water at -5~-3°C at a mass ratio of 1:2, dialyze, take the dialyzate and add sodium bicarbonate at a mass ratio of 5:1 and mix , to get a mixture;

[0033] b. In terms of parts by mass, take 2~5 parts of dental plaque bactericidal enzyme base material, 30~50 parts of tooth cleaning surfactant, 20~30 parts of mixture, 2~5 parts of alkyl glycoside, 1~5 parts of fat Alcohol polyoxyethylene ether-9, 60~80 parts of water, stirred and mixed at 50~60°C for 2~3 hours, and the denture cleaning agent was obtained.

Embodiment 1

[0035] Enteromorpha, sea mud, sea fish, and sea shrimp: taken from Lianyungang waters.

[0036] Crude fish oil: obtained from Qingdao Aofengyuan Feed Co., Ltd., a by-product of fishmeal processing.

[0037]Liquid culture medium: in parts by mass, take 2 parts of yeast powder, 5 parts of peptone, and 1000 parts of seawater, pH 8.0, and sterilize at 121°C for 20 minutes to obtain.

[0038] Primary screening medium: in parts by mass, take 1 part of yeast powder, 5 parts of peptone, 8 parts of dextran 20000, 2 parts of blue dextran, 20 parts of agar, 1000 parts of seawater, pH8.0, sterilized at 121 °C 20min, that is. Fermentation medium: In terms of parts by mass, take 1 part of yeast powder, 5 parts of peptone, 10 parts of dextran 20000, 1000 parts of seawater, pH 8.0, and sterilize at 121°C for 20 minutes. Dental plaque bactericidal enzyme base material: (1) Take enteromorpha and sea mud and add sterile seawater at a mass ratio of 1:2:10, stir and mix for 1 hour to obtain a mi...

Embodiment 2

[0047] Enteromorpha, sea mud, sea fish, and sea shrimp: taken from Lianyungang waters.

[0048] Crude fish oil: obtained from Qingdao Aofengyuan Feed Co., Ltd., a by-product of fishmeal processing.

[0049] Liquid culture medium: in parts by mass, take 4 parts of yeast powder, 9 parts of peptone, and 1000 parts of seawater, pH 8.0, and sterilize at 121°C for 20 minutes to obtain.

[0050] Primary screening medium: in parts by mass, take 5 parts of yeast powder, 9 parts of peptone, 10 parts of dextran 20000, 5 parts of blue dextran, 25 parts of agar, 1000 parts of seawater, pH 8.0, sterilized at 121 °C 20min, that is. Fermentation medium: in parts by mass, take 5 parts of yeast powder, 9 parts of peptone, 15 parts of dextran 20,000, and 1,000 parts of seawater, pH 8.0, and sterilize at 121°C for 20 minutes. Dental plaque bactericidal enzyme base material: (1) Take enteromorpha and sea mud and add sterile seawater in a mass ratio of 1:2:10, stir and mix for 2 hours to obtain a...

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Abstract

The invention discloses a false tooth cleaning agent and a preparation method thereof, and belongs to the field of medicinal preparations. The method is characterized in that enteromorpha, sea mud, marine fish and the like are used as raw materials; dextran 20000 is added to a screening culture medium; a marine strain with enzyme generation function is screened and is subjected to fermenting culture, and thus the enzyme generation activity is improved; the dextran enzyme substances are screened; ad meanwhile, the dextran enzyme substances are capable of desorbing some substances such as tartarattached to false teeth during preventing and treating; the dextran enzyme acts on water soluble glucan in dental plaque biological membrane exopolysaccharides, thus dental plaques on the surfaces ofthe false teeth can be separated, and as a result, the washing and sterilizing effects are achieved; and meanwhile, the adsorbing and corrosion of the dental plaques to the false teeth can be effectively prevented; a false tooth support cannot be corroded during use; the tartar is removed by a natural degrading process; and the problem of low tartar removing capacity and low sterilizing capacityof a current false tooth cleaning agent can be solved.

Description

technical field [0001] The invention belongs to the field of pharmaceutical preparations, and in particular relates to a denture cleaning agent and a preparation method thereof. Background technique [0002] Denture cleaning agent, one of pharmaceutical preparation products. Dentures and denture bases are made of polymethylmethacrylate. Due to the special environment of the oral cavity, dirt such as food protein and pigments are easily deposited on the surface. Moreover, the surface of dentures and bases is not very dense, and there are many micropores, which are easy to embed dirt. It is generally difficult to remove with toothpaste or ordinary detergents. Especially the smoke and tea stains caused by smoking and drinking tea are dark in color, firmly attached, and difficult to remove. [0003] Denture cleaners are daily necessities for denture wearers. The purpose of cleaning dentures is to maintain oral hygiene. Scaling on the surface of dentures is an alkaline struc...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/98A61K8/73A61K8/92A61K8/96A61K8/9706A61Q11/02
CPCA61K8/736A61K8/925A61K8/965A61K8/9706A61K8/987A61K2800/85A61Q11/02
Inventor 雷国平庄文琴丁正颖
Owner CHANGZHOU AMANTE CHEM CO LTD
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