The invention relates to a 1,1,1,3,3-pentafluoropropane (HFC-234fa) refining method. In the method, treatment by activated carbon adsorbent treated by an acid and/alkali is performed to effectively remove unsaturated impurities such as 1-chloro-3,3,3-trifluoropropene (R1233zd), 1-chloro-3,3,3-tetrafluoropropene (R1224zd) and 2-chloro-3,3,3-tetrafluoropropene (R1224xe) in the crude product of HFC-245 fa. The HFC-245fa refining method has the advantages of readily available raw materials, low cost, non-toxicity, environmental friendliness, simple treatment method and the like. The product HFC-245 fa is mainly used to replace HCFC-141b in polyurethane foaming.