The invention relates to a gripping device and method for a high-level sarong to load and unload gauze rolls. The gripping device comprises a base, fixing plates, a lower supporting seat, an upper supporting seat, guide rods, an industrial camera, a centralizing mobile base, fixing rods, a centralizing rod, left yarn gripping grippers, right yarn gripping grippers, left yarn gripping rods, right yarn gripping rods, yarn gripping rod connecting sleeves and a centralizing base. According to the technical scheme, because the height of the guide rods of the high-level sarong is high, the guide rods are inclined after being used for a period of time, the yarn rolls on the guide rods are inclined too, and therefore the yarn rolls are prone to falling down to be damaged when a robot grips the yarn rolls; in addition, because the height of the high-level sarong is high, the yarn rolls also can be damaged caused by overlarge force or falling when a common gripping mechanism grips the yarn rolls. According to the method, the industrial camera is used for positioning yarn gripping and improving the gripping device, therefore, the yarn rolls are avoided from being damaged in the process of yarn gripping of the high-level sarong, and work efficiency and quality are improved.