Patents
Literature
Patsnap Eureka AI that helps you search prior art, draft patents, and assess FTO risks, powered by patent and scientific literature data.

15 results about "Sodium succinate" patented technology

Hydrocortisone Sodium Succinate is used most often as a supportive care medication. Hydrocortisone Sodium Succinate is classified as a glucocorticosteroid. (For more detail, see "How this drug works" section below).

Decontamination and dust fall reagent as well as preparation method and application thereof

The invention discloses a decontamination and dust fall reagent as well as a preparation method and application thereof. The preparation method comprises the following steps: (1) preparing a compound solution: adding ferrous gluconate, sodium alkyl sulfosuccinate, sodium alcohol ether sulfate, lauryl sodium sulfate and polyacrylamide into deionized water according to the mass fraction of 0.10%-0.15%, 0.05%-0.20%, 0.05%-0.15%, 0.10%-0.15% and 0.005%-0.02% respectively to obtain the compound solution; (2) preparing micro-nano bubble water; and (3) adding the compound solution into the micro-nano bubble water in a volume ratio of 1: (0.5-2), and fully mixing the compound solution and the micro-nano bubble water to obtain the decontamination and dust fall reagent. According to the decontaminating and dust-settling reagent prepared by the invention, an environment-friendly surfactant is selected, so that dust can be settled, toxic and harmful gases generated by explosion can be removed by utilizing the characteristic that micro-nano bubble water directly participates in catalytic oxidation, and a good decontaminating and dust-settling effect is achieved.
Owner:NAT HEALTH COMMISSION OCCUPATIONAL SAFETY & HEALTH RES CENT (NAT HEALTH COMMISSION COAL IND OCCUPATIONAL MEDICINE RES CENT)

Indocyanine green preparation, process for its preparation and use

PendingCN122624697ASodium acetateLipid film
The application belongs to the technical field of pharmaceutical preparations, and particularly relates to an indocyanine green preparation and a preparation method and application thereof. The preparation is a liquid preparation or a freeze-dried preparation, raw materials for preparing the preparation include indocyanine green, phospholipid, cholesterol, a freeze-drying protective agent, water and a pH regulator, the pH regulator is selected from one or more of sodium citrate, potassium citrate, sodium tartrate, sodium acetate, sodium lactate and sodium succinate, and the pH of the preparation is adjusted to 6.0-8.5. By means of a specific organic acid salt buffer system and a specific preparation process (the freeze-drying protective agent is added before lipid film deposition), the application can specifically inhibit the growth of impurities with RRT 0.7 and RRT 0.3, respectively, and significantly improve the chemical stability of the preparation. Meanwhile, the preparation can realize accurate positioning of sentinel lymph nodes and second and third lymph nodes, and can be used for preparing a lymph tracer. The application effectively solves the technical problems of rapid impurity growth, poor stability and inaccurate multi-stage lymph positioning of the existing ICG preparation.
Owner:SHENYANG JUNHONG PHARM TECH CO LTD +2

Bionic shark fin flavor essence, probiotic microcapsule, preparation process of bionic shark fin flavor essence and probiotic microcapsule, and instant seasoning

The invention discloses bionic shark fin flavor essence, a probiotic microcapsule, a preparation process of the bionic shark fin flavor essence and the probiotic microcapsule and an instant seasoning. The bionic shark fin flavor essence is prepared from the following components in percentage by weight: 0.5%-1.5% of L-alanine, 0.3%-1.0% of glycine, 0.05%-0.4% of disodium 5 '-inosinate, 0.05%-0.4% of disodium 5'-guanylate and 0.1%-0.8% of sodium succinate. 1%-5% of yeast extract, 2%-8% of mushroom mycelium fermentation liquor, 0.05%-0.3% of ginger oleoresin and 0.03%-0.25% of garlic oleoresin; 20%-55% of propylene glycol and 5%-15% of sorbitol; 0.2%-3% of probiotic microcapsules subjected to embedding treatment; and the balance of deionized water. According to the bionic shark fin flavor essence provided by the invention, through an elaborately designed plant base and fermentation source formula, the dependence of the traditional shark fin flavor on seafood extracts is completely avoided, the seafood allergen risk is completely eradicated, and the consumption requirements of special crowds are met.
Owner:DONGGUAN POLYTECH FOOD ADDITIVES CO LTD

Amphiphilic polycarbonate polyol as well as preparation method and application thereof

PendingCN121609896APolymer scienceAdhesive
The invention provides amphiphilic polycarbonate polyol as well as a preparation method and application thereof. The amphiphilic polycarbonate polyol is prepared from 100 parts by mole of carbonic acid diester, 3-50 parts by mole of alkyl sulfonic acid sodium succinate and 110-400 parts by mole of polyol raw materials through ester exchange and condensation polymerization. According to the invention, the special monomer alkyl sulfonic sodium succinate is used, the prepared polycarbonate polyol contains a sulfonate structure, waterborne polyurethane can be prepared without waterborne chain extension, and the polycarbonate polyol is free of a benzene ring structure and low in product viscosity; meanwhile, the prepared polycarbonate polyol is subjected to devolatilization treatment, the content of small molecular impurities is low, side reactions in the polyurethane preparation process are few, and the prepared polyurethane material has the characteristics of low odor and low VOC (volatile organic compound) and can be applied to the industries of leather, coatings, adhesives and the like.
Owner:WANHUA CHEM GRP CO LTD

Controlled-release nitrogen fertilizer containing organic acid salt signal substance

This invention discloses a controlled-release nitrogen fertilizer containing organic acid salt signaling substances. From the inside out, it comprises urea particles, a cross-linked material-trace element mixture, molten urea, and a bio-based polyurethane coating material. The cross-linked material-trace element mixture is a porous cross-linked material loaded with trace elements. The porous cross-linked material is obtained by cross-linking alginic acid and organic acid salts through a cross-linking agent. The organic acid salts are selected from at least one of sodium citrate, sodium fumarate, sodium maleate, sodium malonate, and sodium succinate. The trace elements are selected from at least one of zinc, cobalt, molybdenum, and iron. This invention, through alginic acid-organic acid salt cross-linking, precise loading of trace elements, and multi-layer coating technology, produces a novel controlled-release fertilizer that combines pH responsiveness, environmental resistance, and high nutrient utilization. Nutrient release can be dynamically controlled according to soil pH and crop needs, reducing nutrient loss and environmental pollution, meeting the needs of green agriculture development, and providing an innovative solution for improving fertilizer utilization and crop yield.
Owner:SHANDONG AGRICULTURAL UNIVERSITY

Acinetobacter pittii AP-3 and application thereof

This invention belongs to the field of biotechnology and discloses a heterotrophic nitrifying-aerobic denitrifying Acinetobacter pittii AP-3 and its applications. The Acinetobacter pittii AP-3 has the accession number GDMCC No: 68038, taxonomical name Acinetobacter pittii, accession date April 2, 2026, and is deposited at the Guangdong Provincial Microbial Culture Collection Center, located at 5th Floor, Building 59, No. 100, Xianlie Middle Road, Guangzhou. The Acinetobacter pittii AP-3 provided by this invention exhibits good heterotrophic nitrification-aerobic denitrification performance. Under conditions of 30℃, C / N ratio of 25, sodium succinate as the carbon source, 5% inoculum size, and pH 7, when treated with a heterotrophic nitrification-aerobic denitrification medium (SNDM), NO2... ‑ The removal rate of NO3- concentration reached 98.52% after 24 hours. ‑ -N concentration removal rate reaches over 95%, NH4 + The nitrogen removal rate reached 100%. Moreover, the AP-3 strain has high tolerance to pH, and exhibits good denitrification effect in the pH range of 5 to 9.
Owner:INST OF ANIMAL HEALTH GUANGDONG ACADEMY OF AGRI SCI

Succinylation modification of RAD51 protein, formulations that promote RAD51 succinylation and their applications

This invention relates to the field of biomedical technology, disclosing succinylated modified RAD51 protein, formulations for promoting RAD51 succinylation, and their applications. The method includes: seeding and culturing cells and transfecting them with a tagged RAD51 expression plasmid; adding sodium succinate and an HDAC11 inhibitor to the culture medium for continued culturing to allow intracellular modification accumulation; collecting the supernatant after cell lysis and incubating it with magnetic beads containing anti-tag antibodies under cold conditions; washing and eluting with an elution buffer containing the tagged peptide; performing immunoblotting analysis using antibodies that specifically recognize the modified site to obtain the succinylated modified RAD51 protein. This invention, by adding sodium succinate and an HDAC11 inhibitor, provides a substrate and blocks the demodification pathway. Combined with magnetic bead purification and competitive elution, it avoids disrupting the protein conformation, obtaining a protein that retains its native activity and has a high level of modification, providing a core component for screening targeted drugs.
Owner:SHANGHAI EAST HOSPITAL EAST HOSPITAL TONGJI UNIV SCHOOL OF MEDICINE

Double-gel-system pre-makeup cream as well as preparation method and application thereof

PendingCN121337672ACosmetic preparationsToilet preparationsCelluloseIsostearyl alcohol
The invention belongs to the technical field of cosmetics, and particularly relates to double-gel-system pre-makeup cream as well as a preparation method and application thereof. The invention relates to a double-gel system makeup cream, which is at least prepared from the following ingredients in parts by mass: 4 to 20 parts of skin moistening grease, 0.2 to 1 part of hydrogenated castor oil isostearate, 1.0 to 3 parts of isostearyl alcohol / butanediol cocoate / ethyl cellulose compounds and 0.5 to 2 parts of hydroxypropyl starch phosphate / starch sodium octenylsuccinate compounds. The double-gel-system pre-makeup cream prepared by matching the specific components according to a specific proportion has the moisturizing and skin-attaching effects of a water-in-oil system and the refreshing and breathable effects of an oil-in-water system; secondly, the system does not need to add an emulsifier, is free of silicone oil and silicon elastic components, is natural and safe, and can be used for sensitive skin; and finally, the system can intelligently regulate and control the oil-water balance of the face, so that the face is more fit in makeup keeping, the makeup keeping problems such as face powder blocking, makeup dizziness and floating powder are solved, and therefore, the system has good practical application value.
Owner:SHANDONG FREDA BIOTECH CO LTD

A method for improving the efficiency of potato tissue culture stem propagation

The application provides a method for improving the propagation efficiency of potato tissue culture stems, which comprises the following steps: taking an aseptic stem segment of Atlantic variety as an explant, inoculating into a pH 5.8 MS basic culture medium containing 3.0% sucrose and 7 g / L agar, supplementing the culture container with an optimized culture solution containing 100 mg / L calcium nitrate and 3.0% sucrose for three times at the 0th, 5th and 10th days of culture, culturing for 20 days under the conditions of 24 DEG C, 16 h light / 8 h darkness and 4000 lux, using alginate microcarriers to load active ingredients, adding selenium carbon black and sodium succinate under the protection of nitrogen through staged temperature control stirring, preparing through 25 DEG C light-shielded maturation and sterile filtration, and the terminal dissolved oxygen content is less than or equal to 0.5 ppm. The method significantly shortens the culture period of potato stems, improves the propagation efficiency, and is suitable for large-scale production of virus-free seed potatoes.
Owner:INNER MONGOLIA HUACHEN AGRICULTURAL TECHNOLOGY CO LTD

A method for improving the yield of natamycin fermentation

The present application relates to natamycin production technical field, specifically to a method for improving natamycin fermentation yield, comprising the following steps: shake flask seed culture: under sterile conditions, brown yellow spore streptomyces spores are coated on agar medium, and placed in a culture box for culture, then the cultured brown yellow spore streptomyces is prepared into spore suspension, and the spore suspension is taken and added into a triangular flask of seed culture medium for culture; fermentation tank fermentation culture: the cultured seed liquid is inoculated into a fermentation culture medium comprising proteose peptone, yeast powder, sodium chloride, magnesium sulfate, glucose, betaine, ampicillin, sodium succinate for stirring culture, and glucose is added during the culture until the fermentation is completed, and natamycin is obtained. The present application significantly improves the yield of brown yellow spore streptomyces producing natamycin by adding betaine, ampicillin and sodium succinate in the fermentation culture medium; the production method is simple to operate and is conducive to large-scale industrialization.
Owner:SHANDONG FREDA BIOTECH

Method for extracting cellulose from biomass waste residue

The invention belongs to the technical field of biomass waste reutilization, and discloses a method for extracting cellulose from biomass waste residue, which is characterized by comprising the following steps: S1, adding buffer salt into alkali liquor to promote lignin to be dissolved in low-concentration alkali liquor, the buffer salt is a mixed solution of urea, sodium citrate and sodium succinate, and the buffer salt is a mixed solution of urea, sodium citrate and sodium succinate; then putting the biomass waste residues and alkali liquor into a reaction kettle, heating, stirring and preserving heat to obtain a mixed suspension containing cellulose; and S2, carrying out solid-liquid separation on the mixed suspension obtained in S1 to obtain filter residues and a lignin solution, washing the filter residues, and carrying out solid-liquid separation to obtain a washing solution and a cellulose product. The method for extracting the cellulose from the biomass waste residues has the advantages of high efficiency, low cost, low pollution, high recovery rate of the cellulose, high purity and the like.
Owner:DANISCO SWEETENERS (ANYANG) CO LTD

Zeolite-loaded bacterial spore microcapsule, preparation thereof and application of zeolite-loaded bacterial spore microcapsule in wastewater remediation

The invention provides a zeolite loaded bacterial spore microcapsule and a preparation method thereof, the microcapsule takes zeolite as a skeleton structure, bacterial spores are embedded in the skeleton formed by the zeolite, and nutrient substances are loaded on the outer surface of the skeleton; wherein the bacterial spores are bacillus pasteurii spores, and the nutrient substances comprise sodium succinate, inosine, Ni < 2 + > and Mn < 2 + >. The invention also provides application of the microcapsule in wastewater remediation. Through coordination of zeolite adsorption and bacterial spore activation, efficient and synchronous restoration of the lead-containing ammonia nitrogen composite wastewater is realized: on one hand, zeolite absorbs part of lead ions in the early stage to reduce the toxicity of the zeolite to spores and also absorbs ammonia nitrogen byproducts generated by urea hydrolysis by virtue of porous high adsorbability; on the other hand, the spores are resistant to a severe environment, germinate into nutritional cells after the lead concentration is reduced, catalyze urea hydrolysis to produce carbonate radicals and solidify residual lead into stable carbonate, and finally, the dual effects of lead deep solidification and ammonia nitrogen removal are achieved.
Owner:TONGLING UNIV

Microbial fermentation culture medium and culture method for increasing yield of gamma-aminobutyric acid

The invention belongs to the technical field of culture media, and particularly relates to a microbial fermentation culture medium for improving the yield of gamma-aminobutyric acid, which comprises the following components by concentration: 10-12g / L of glucose, 5-7g / L of sodium succinate, 14-16g / L of yeast extract powder, 14-16g / L of tryptone, 15g / L of sodium glutamate and an ion additive, wherein the ion additive is added according to the condition that every 20mL of the culture medium contains 0.6 to 0.9 mL of Ca < 2 + >, 0.4 to 0.6 mL of K < + >, 0.3 to 0.5 mL of P < 3 + >, 0.5 to 0.8 mL of Mg < 2 + > and 0.4 to 0.5 mL of Mn < 2 + >. According to the culture medium, the yield of gamma-aminobutyric acid (GABA) can be remarkably increased, the problem that the yield of traditional fermentation is low is solved, and the large-scale production requirement is met.
Owner:NANJING TECH UNIV

Efficient denitrification heterotrophic nitrification-aerobic denitrification bacterium and denitrification application thereof

PendingCN121406537ABacteriaWater contaminantsButanedioic acidAchromobacter animicus
The invention discloses a high-efficiency denitrification heterotrophic nitrification-aerobic denitrification bacterium and denitrification application thereof, and relates to the technical field of microbial denitrification. The strain is Achromobacter insolitus H5-1, the preservation number of the Achromobacter insolitus H5-1 is CGMCC (China General Microbiological Culture Collection Center) No.36087, and the 16S rRNA (Ribose Nucleic Acid) gene sequence of the Achromobacter insolitus H5-1 is shown as SEQ ID NO.1 in a sequence table. The strain can be used for synchronous nitrification and denitrification under the aerobic condition, ammonia nitrogen, nitrate nitrogen and nitrite nitrogen can be efficiently degraded, the degradation rate of the ammonia nitrogen within 24 hours reaches 99% or above, the degradation rate of the nitrate nitrogen reaches 85% or above, and nitrite nitrogen accumulation is avoided. The optimal culture conditions are as follows: the carbon source is selected from sodium pyruvate or sodium succinate, the C / N ratio is 15, the pH value is 7.0-8.0, the temperature is 25-35 DEG C, and the rotating speed is 140-180 rpm. The strain can be used for aquaculture tail water, fishery water quality regulation and control and nitrogen-containing sewage treatment.
Owner:THIRD INSTITUTE OF OCEANOGRAPHY STATE OCEANI C ADMINISTRATION

Temporary plugging type workover fluid as well as preparation method and application thereof

The invention relates to temporary plugging type workover fluid as well as a preparation method and application thereof, and belongs to the technical field of oil production engineering. The temporary plugging type workover fluid comprises the following components in percentage by mass: 0.4-2% of a discharge aiding agent, 2.5-5% of an oil-soluble temporary plugging agent, 0.04-0.1% of a filtrate reducer and the balance of water, wherein the cleanup additive is prepared from sodium dioctyl sulfosuccinate and alkyl glucoside; the oil-soluble temporary plugging agent comprises EVA (Ethylene Vinyl Acetate) resin, C9 petroleum resin and calcium carbonate; the filtrate reducer comprises hydrolyzed polyacrylamide. The EVA resin and the C9 petroleum resin are compounded to serve as the oil-soluble temporary plugging agent, meanwhile, the discharge aiding agent and the filtrate reducer are combined, the temporary plugging type workover fluid for medium-high permeability heavy oil reservoirs is formed, and compared with a conventional workover fluid, the temporary plugging type workover fluid has better compatibility to the heavy oil reservoirs and can be applied to workover operation of the medium-low temperature heavy oil reservoirs.
Owner:PETROCHINA CO LTD