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Red ginseng and radix paeoniae alba Qi-benefiting and blood-nourishing granule traditional Chinese medicine composition and preparation method thereof

A technology for nourishing qi and nourishing blood and a composition, applied in the directions of drug combination, pharmaceutical formula, blood diseases, etc., can solve the problems of side effects, unsatisfactory effect of aplastic anemia, etc., and achieve any toxic side effects, no toxic side effects, and clear efficacy. Effect

Inactive Publication Date: 2018-09-04
陕西郝其军制药股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The inventor has done a lot of research on the prior art, and found that the curative effects of the three treatments for aplastic anemia disclosed in the above patent bulletin are not satisfactory, and have some side effects

Method used

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  • Red ginseng and radix paeoniae alba Qi-benefiting and blood-nourishing granule traditional Chinese medicine composition and preparation method thereof
  • Red ginseng and radix paeoniae alba Qi-benefiting and blood-nourishing granule traditional Chinese medicine composition and preparation method thereof
  • Red ginseng and radix paeoniae alba Qi-benefiting and blood-nourishing granule traditional Chinese medicine composition and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0262] The present invention is made from the raw material medicine of following weight ratio:

[0263]

[0264] Its preparation method is as follows:

[0265] The above twelve flavors are decocted twice with water, the first time is 1.5 hours, add 8 times the amount of water, and the second time is 1 hour, add 6 times the amount of water, combine the decoction, filter, and measure the relative density when the filtrate is concentrated to 60°C It is a clear paste of 1.20-1.25, dried under reduced pressure at 70°C, and crushed into a fine powder; take the extract powder, dextrin, and sucrose powder and mix them in a ratio of 1:0.5:1, make granules with 80% ethanol, and dry. Whole grains, made into 1000g, divided into granules to obtain granules.

Embodiment 2

[0267] The present invention is made from the raw material medicine of following weight ratio:

[0268]

[0269] Its preparation method is as follows:

[0270] The above twelve flavors are decocted twice with water, the first time is 1.5 hours, add 8 times the amount of water, and the second time is 1 hour, add 6 times the amount of water, combine the decoction, filter, and measure the relative density when the filtrate is concentrated to 60°C It is a clear paste of 1.20-1.25, dried under reduced pressure at 70°C, and crushed into a fine powder; take the extract powder, dextrin, and sucrose powder and mix them in a ratio of 1:0.5:1, make granules with 80% ethanol, and dry. Whole grains, made into 1000g, divided into granules to obtain granules.

Embodiment 3

[0272] The present invention is made from the raw material medicine of following weight ratio:

[0273]

[0274] Its preparation method is as follows:

[0275] The above twelve flavors are decocted twice with water, the first time is 1.5 hours, add 8 times the amount of water, and the second time is 1 hour, add 6 times the amount of water, combine the decoction, filter, and measure the relative density when the filtrate is concentrated to 60°C It is a clear paste of 1.20-1.25, dried under reduced pressure at 70°C, and crushed into a fine powder; take the extract powder, dextrin, and sucrose powder and mix them in a ratio of 1:0.5:1, make granules with 80% ethanol, and dry. Whole grains, made into 1000g, divided into granules to obtain granules.

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Abstract

The invention discloses a red ginseng and radix paeoniae alba Qi-benefiting and blood-nourishing granule traditional Chinese medicine composition and a preparation method thereof. The traditional Chinese medicine composition is prepared by twelve raw material medicines, namely red ginseng, radix paeoniae alba, astragalus membranaceus, prepared rehmannia root, angelica sinensis, herba epimedii, morinda officinalis, teasel root, semen cuscutae, hairyvein agrimony, fried atractylodes rhizome and fructus amomi, and granules are prepared by water extraction, clear paste drying, crushing, adding dextrin and saccharose for uniform mixing and sub-package sequentially. The red ginseng and radix paeoniae alba Qi-benefiting and blood-nourishing granule traditional Chinese medicine composition is better in curative effect, reasonable in compatibility, synergistic in effect, explicit in efficacy, safe without any toxicand side effect, high in safety in case of long-term medication and incapable ofgenerating dependence. The red ginseng and radix paeoniae alba Qi-benefiting and blood-nourishing granule traditional Chinese medicine composition disclosed by the invention has the efficacies of benefiting Qi, promoting the secretion of saliva or body fluid, invigorating bone marrow to generate blood, tonifying kidney and Yang, tonifying spleen and invigorating stomach and is used for treating aplastic anemia, a myelodysplastic syndrome, thrombocytopenia, radiochemotherapy-induced hematopenia, Qi and blood deficiency and kidney-Yang insufficiency.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition of Shenshao Yiqi Yangxue Granules and a preparation method thereof, belonging to the technical field of pharmacy. Background technique [0002] Aplastic anemia (AA), referred to as "aplastic anemia", is a syndrome in which the number of hematopoietic stem cells is reduced or the function is abnormal due to various reasons, thereby causing PB red blood cells, white blood cells and thrombocytopenia. It is a common and frequently-occurring disease of the blood system, accounting for 12.6% of blood system diseases. It is also a disease with a long course and difficult treatment. The main clinical manifestations are anemia, bleeding and infection. According to survey data, the worldwide incidence rate is 0.2-0.5 / 100,000 population, and 1.2 / 100,000 population in the United States and other industrialized countries. The annual incidence rate of aplastic anemia in my country is 0.74 / 100,000 p...

Claims

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Application Information

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IPC IPC(8): A61K36/9064A61K9/16A61P7/06A61P7/00A61P7/04
CPCA61K9/1652A61K36/185A61K36/232A61K36/258A61K36/284A61K36/296A61K36/39A61K36/43A61K36/481A61K36/65A61K36/71A61K36/73A61K36/746A61K36/804A61K36/9064A61K2236/331A61K2236/39A61K2236/51A61P7/00A61P7/04A61P7/06A61K2300/00
Inventor 郝彬
Owner 陕西郝其军制药股份有限公司
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