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Chitosan composition and preparation method thereof

A technology of chitosan and composition, which is applied in the field of chitosan composition and its preparation, can solve the problems of the loss of the hypoglycemic function of western medicine, unsuitable selection of synthetic drugs, hypoglycemia, etc., and achieve energy saving, convenient operation, and process simple effect

Active Publication Date: 2018-09-07
GUANGDONG PHARMA UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Many diabetic patients take western medicine for a long time, and gradually lose their effect on the hypoglycemic function of western medicine
In addition, some patients taking western medicine will lead to hypoglycemia, and some patients are not suitable for synthetic drugs due to the defects of liver and kidney function.

Method used

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  • Chitosan composition and preparation method thereof
  • Chitosan composition and preparation method thereof
  • Chitosan composition and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] A kind of chitosan composition, its raw material consists of:

[0029] Chitosan 5g, L-carnitine tartrate 4g, kidney bean extract 10g, ginsenoside extract 6g.

[0030] The preparation method of the kidney bean extract described therein comprises the steps:

[0031] Take kidney beans and crush them through a 40-mesh sieve, add 10 times the volume of medicinal materials and soak in 60% ethanol aqueous solution for 0.5 hours, extract at 40°C, extract once, and each extraction time is 1 hour, filter, combine the filtrates, and extract the combined solution Concentrate under reduced pressure and dry in vacuum to obtain the kidney bean extract.

[0032] The preparation method of the ginsenoside extract described therein comprises the steps:

[0033] Take fresh ginseng to remove foreign matter, wash it with clean water, chop it, add 60% methanol aqueous solution 6 times the volume of the medicinal material, soak for 1 hour, heat and reflux for extraction once, each extraction...

Embodiment 2

[0037] A kind of chitosan composition, its raw material consists of:

[0038] Chitosan 15g, L-carnitine tartrate 10g, kidney bean extract 20g, ginsenoside extract 12g.

[0039] The preparation method of the kidney bean extract described therein comprises the steps:

[0040] Take kidney beans and crush them through a 60-mesh sieve, add 15 times the volume of medicinal materials and soak in 60% ethanol aqueous solution for 2 hours, extract at 60°C, extract 3 times, each extraction time is 3 hours, filter, combine the filtrates, and extract the combined solution Concentrate under reduced pressure and dry in vacuum to obtain the kidney bean extract.

[0041] The preparation method of the ginsenoside extract described therein comprises the steps:

[0042] Take fresh ginseng to remove foreign matter, wash it with clean water, chop it, add 60% methanol aqueous solution 10 times the volume of the medicinal material, soak for 2 hours, heat and reflux extraction 3 times, each extracti...

Embodiment 3

[0046] A kind of chitosan composition, its raw material consists of:

[0047] Chitosan 10g, L-carnitine tartrate 6g, kidney bean extract 15g, ginsenoside extract 9g.

[0048] The preparation method of the kidney bean extract described therein comprises the steps:

[0049] Take kidney beans and crush them through a 50-mesh sieve, add 12 times the volume of medicinal materials and soak in 60% ethanol aqueous solution for 1.2 hours, extract at 50°C, extract twice, each extraction time is 2 hours, filter, combine the filtrates, and extract the combined solution Concentrate under reduced pressure and dry in vacuum to obtain the kidney bean extract;

[0050] The preparation method of the ginsenoside extract described therein comprises the steps:

[0051] Take fresh ginseng to remove foreign matter, wash it with clean water, chop it, add 60% methanol aqueous solution 8 times the volume of the medicinal material, soak for 1.5 hours, heat and reflux extraction twice, each extraction ...

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Abstract

The invention relates to the technical field of medicine, and particularly relates to a chitosan composition and a preparation method thereof. Through screening, it is found that the composition composed of chitosan, L-carnitine-L-tartrate, kidney bean extract and ginsenoside extract has significant weight reducing and blood glucose reducing effects. Toxicity experiments prove that the chitosan composition is safe and non-toxic; the preparation method has the advantages of simple process, convenient operation, energy saving and popularization and application.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a chitosan composition and a preparation method thereof. Background technique [0002] Due to the improvement of people's living standards, unreasonable nutritional structure and other factors, obesity has become a modern civilized disease with a high incidence rate. Especially in recent years, the number of obese patients in my country has increased very rapidly, and in some areas it has reached more than 30%. , and the problem of adolescent obesity has become increasingly prominent. Obesity not only affects the appearance, but also threatens health, which can lead to the occurrence of many diseases. [0003] Diabetes has become an epidemic of increasing concern in recent years. According to the statistics of the World Health Organization, more than 200 million people worldwide suffer from diabetes, and it is estimated that this number will double by 2030. According to a repo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/48A61P3/10A61P3/04A61K31/205A61K31/722
CPCA61K31/205A61K31/722A61K36/258A61K36/48A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61P3/04A61P3/10A61K2300/00
Inventor 苏政权
Owner GUANGDONG PHARMA UNIV
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