Latent chiral bridged perfluoroaryl borate compound and preparation thereof
A technology of perfluoroaryl borate and magnesium perfluoroaryl borate, which is applied in the field of organic compounds and its preparation, can solve the problem of structural modification and functional modulation of perfluorophenyl borate without the control of stereoselectivity and other problems, to achieve the effect of increasing adjustable performance, simple synthesis route, and high degree of functionalization
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Embodiment 1
[0032]Under anhydrous and oxygen-free conditions, 100 mL of solvent n-pentane was added to a 250 mL reaction flask, 2-butyne (0.1 mol, 7.8 mL) was added, and dichloroborane dioxane ( 3M dichloromethane solution, 0.1mol, 33.3mL), reacted for 5h, and obtained 14.6g of the product after removing the solvent, with a yield of 67%. used directly in the next reaction.
[0033] Under anhydrous and oxygen-free conditions, dissolve 0.06 mol (13.2 g) of the obtained product in 100 mL of n-pentane, adjust the temperature to -78 °C, then add 0.3 mol of perfluoroaryllithium reagent, and slowly rise to room temperature to continue the reaction 1- After 48 hours, filter, wash with n-pentane, combine the filtrates, and remove the solvent to obtain 35.2 g of the product, with a yield of 79%. used directly in the next reaction.
[0034] Under anhydrous and oxygen-free conditions, in a 250mL reaction flask, add 100mL of solvent tetrahydrofuran, add 2.1g (0.085mol) of magnesium metal and a catal...
Embodiment 2
[0039] Substitute tetra-n-butylammonium chloride in embodiment 1 with the triethylamine hydrochloride of equimolar quantity, other conditions are the same as embodiment 1, obtain solid 22.1g, be a kind of latex shown in formula (1) Sexually bridged perfluorophenyl borate.
[0040] The spectrogram data is as follows:
[0041] 13 C NMR(125MHz,Common NMR Solvents)δ161.66,155.07,155.69,155.68,155.67,155.65,146.00,146.05,146.02,145.98,136.77,136.76,136.74,136.73,136.48,111.46,70.97,70.96,56.04,45.18 , 31.24, 14.92, 11.26, 10.41.
Embodiment 3
[0043] Substitute tetrahydrofuran in Example 1 with diethyl ether of equal volume, replace the toluene in Example 1 with dichloromethane of equal volume, and other conditions are the same as Example 1, and finally obtain 24.5 g of viscous solid, which is represented by formula (1). A latent chiral bridged perfluorophenyl borate is shown.
[0044] product of 13 C NMR is the same as the product of Example 1.
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