A kind of method for synthesizing glycine by continuous rapid alkaline hydrolysis of aminoacetonitrile

Abstract

The invention provides a method for synthesizing glycine by performing alkaline hydrolysis on aminoacetonitrile continuously and rapidly. The method comprises the following steps: adding alkali and aminoacetonitrile into a microchannel reactor, controlling the reaction temperature to 100 to 160 DEG C and the pressure to 0.1 to 0.5 MPa and enabling the retention time of the reactants in the microchannel to be 1 to 10 minutes to obtain the glycine. The microchannel reactor is adopted, so that the alkaline hydrolysis time of the aminoacetonitrile is greatly shortened, and pyrolysis olymerizationof the aminoacetonitrile and generation of byproducts are reduced; and the alkaline hydrolysis reaction rate is increased, the yield of products is increased and the production cost is reduced.

Description

technical field [0001] The invention relates to the field of chemical industry, in particular to a method for synthesizing glycine by continuous rapid alkali hydrolysis of aminoacetonitrile. Background technique [0002] Glycine is the amino acid with the simplest structure, and it is widely used in pesticides, food, medicine, and feed additives. Especially with the maturity of the synthesis of glyphosate by glycine method, the demand for glycine will be greater, and the demand for glycine will be greater. There are many preparation techniques, such as Chinese patent CN1962611A discloses a technique for preparing glycine by hydroxyacetonitrile method, including the following steps: 1) mixing hydroxyacetonitrile and ammonia water, and the molar ratio of the reaction liquid is hydroxyacetonitrile:ammonia=1:2 ~10, control the reaction temperature between 20~60 ℃, the reaction time is 0.5~8 hours, obtain the ammoniacal solution of aminoacetonitrile; 2) directly add inorganic bas...

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Problems solved by technology

[0003] In view of the above-mentioned shortcoming of the prior art, the purpose of the present invention is to provide a kind of method for the synthesis of glycine by continuous rapid alkaline hydrolysis of aminoacetonitrile, which is used to solve the problem that raw materials are easy to decompose, thermally decompose and polymerize when synthesizing glycine in the prior art, and easily produce By-products, slow reaction rate, easy to cause the formation of colored impurities, etc.

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