Fluorescence imaging detection instrument

Abstract

The invention relates to a fluorescence imaging detection instrument, which comprises a camera bellow structure. During the detection, a sample tray is arranged in a carrying region in a camera bellow; during the camera bellow environment detection, the contrast degree is high; the fluorescence signal can be well detected even when the fluorescence signal is very weak; the influence by vision errors and environment brightness factors cannot easily occur; the anti-interference capability to the environment light signals can be greatly improved; the detection result accuracy can be improved; thefluorescence imaging instrument can drive a camera to move through controlling the action of a transverse movement assembly and a longitudinal movement assembly, so that the regional shooting imagingcan be performed on the sample tray; after the shooting imaging of each region is completed, the stored pattern of each region is integrated to obtain the whole pattern; the connection with a computer system can be realized to perform image analysis treatment and to generate detection results. The fluorescence imaging detection instrument can shoot and image a plurality of results in one step; the detection flux is high; the manual observation and comparison one by one is not needed; the detection efficiency is obviously improved.

Description

technical field [0001] The invention relates to the field of biochemical detection, in particular to a fluorescence imaging detector. Background technique [0002] Human papillomavirus (HPV) is a double-stranded circular DNA virus containing about 8000 base pairs. There are more than 100 types, and it is a class of tumor-causing viruses. According to the degree of tumorigenesis, it is divided into high-risk HPV and low-risk HPV, at least 14 of which can cause cancer (also known as high-risk type, that is, high-risk type), and are often detected in cervical tumors, which seriously threaten the health of women. Its long-term infection is an important cause of cervical cancer. Long-term infection is a gradual process. Early infection clearance can reduce or avoid cancer, and can also be treated symptomatically. Especially in the current situation where the incidence rate is increasing and the trend is younger, the screening, prevention, diagnosis and treatment of HPV are impor...

AI Technical Summary

Problems solved by technology

[0003] Traditional HPV nucleic acid detection methods mainly use PCR fluorescence method and PCR-reverse dot hybridization method, and the comparison results are mainly read manually during detection. Manual reading has a large error rate in the detection results, high difficulty in operation, and is easily affected by the outside world. Due to the influence of experimental environment factors, long detection time, low efficiency and other shortcomings, it has a certain impact on the accuracy and detection efficiency of the read detection results.

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