Cordyceps militaris extract as well as preparation method and application and cordyceps militaris drink

A technology of Cordyceps militaris and extract solution, which is applied in the fields of application, food ingredients containing natural extracts, blood diseases, etc., can solve the problems of obvious side effects, long treatment course, liver and kidney damage, etc., achieve good thrombosis tendency, and simple preparation method , the effect of reversing the tendency of thrombosis

Inactive Publication Date: 2018-11-20
QIQIHAR UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Existing conventional thrombosis drugs such as tissue plasminogen activator (t-PA), t-PA mutant (reteplase reteplase), rt-PA chimera, etc. are not only expensive, but also have a long course of treatment. Moreover, the side effects are obvious, the damage to the liver and kidney is greater, and it is easy to cause risks such as cerebral hemorrhage.

Method used

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  • Cordyceps militaris extract as well as preparation method and application and cordyceps militaris drink
  • Cordyceps militaris extract as well as preparation method and application and cordyceps militaris drink

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preparation example Construction

[0023] The invention provides a kind of preparation method of Cordyceps militaris extract, comprises the steps:

[0024] (1) drying and pulverizing the mycelium of Cordyceps militaris to obtain the powder of Cordyceps militaris;

[0025] (2) Mix the Cordyceps militaris powder with water in proportion, mix 40-60 mL of water per 1 g of the Cordyceps militaris powder, extract for 1-3 hours, and separate the solid and liquid to obtain a supernatant and a solid residue;

[0026] (3) Mix the solid residue with water in proportion, mix 20-30 mL of water per 1 g of solid residue, extract for 1-3 hours, and separate the solid and liquid to obtain the secondary supernatant;

[0027] (4) The primary supernatant and the secondary supernatant are combined to obtain an extract of Cordyceps militaris.

[0028] In the present invention, the Cordyceps militaris mycelium is preferably dried first. In the present invention, the drying temperature is preferably 30-40° C., more preferably 35° C....

Embodiment 1

[0048] Dry and crush the mycelium of Cordyceps militaris, pass through a 60-mesh sieve, extract with water for 2 hours at 60°C and a material-to-liquid ratio of 1:50, cool, and centrifuge at 10,000r / min for 15 minutes to obtain a supernatant, according to the material-to-liquid ratio Add water to the precipitate at 1:25, extract again under the same conditions for 2 hours, cool, and centrifuge at 10,000r / min for 15 minutes to obtain the supernatant, and combine the two supernatants to obtain the Cordyceps militaris extract.

Embodiment 2

[0050] (1) The fibrin plate method was used to prove that the extract of Cordyceps militaris had the effect of dissolving fibrin.

[0051] The fibrin plate contains fibrinogen and thrombin. The soluble fibrinogen forms fibrin monomers under the action of thrombin. The fibrin monomers spontaneously associate and polymerize to form insoluble macroscopic blood fibers. For the protein gel, the extract of Cordyceps militaris described in Example 1 is added to the surface of the slab gel, and after a short period of cultivation, the fibrin can be dissolved to form a transparent dissolution circle visible to the naked eye on the surface of the slab gel.

[0052] Preparation of fibrin plate: Take the preparation of 10 plates as an example, dissolve 0.25g of agarose in 50mL of normal saline, put it in a water bath at 45°C for 30min, then add 200U of thrombin and mix well; 0.2g of bovine blood fiber Dissolve proteinogen in barbital sodium buffer (pH 7.8), place it in a water bath at 45°...

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Abstract

The invention provides a cordyceps militaris extract as well as a preparation method and application and a cordyceps militaris drink and belongs to the technical field of food drink processing. The preparation method of the cordyceps militaris extract comprises the following steps: by taking cordyceps militaris mycelium as a raw material, drying, crushing, and carrying out twice water extraction,thereby obtaining the cordyceps militaris extract. The preparation method provided by the invention is simple to operate and good in repeatability. The cordyceps militaris extract provided by the invention has plasmin activity of 3-5U/mL and has a good thrombus tendency reversion function.

Description

technical field [0001] The invention belongs to the field of food and beverage processing, and in particular relates to a cordyceps militaris extract, a preparation method and application thereof, and a cordyceps militaris beverage. Background technique [0002] Cordyceps militaris, also known as Cordyceps militaris, is a model species of the genus Cordyceps, and belongs to the genus Cordyceps (Cordyceps) in taxonomy. Cordyceps militaris contains nutrients such as Cordyceps polysaccharides, cordycepin, nucleosides, sterols and other biologically active substances such as essential amino acids, vitamins and superoxide dismutase (SOD). It has good effects on prolonging sleep, anti-inflammation, anti-cancer, anti-bacterial, anti-aging, etc. It is a good nutrition and nourishing product. [0003] In recent years, with the aging of the social population and the continuous improvement of living standards, the incidence of hyperlipidemia, atherosclerosis and the resulting heart an...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/068A61P7/02A23L2/38A23L2/52A23L2/68A23L31/00A23L33/00
CPCA61P7/02A23L2/38A23L2/52A23L2/68A23L31/00A23L33/00A61K36/068A23V2002/00A61K2236/331A61K2236/39A23V2250/208A23V2200/326A23V2200/322A23V2200/30A23V2250/21
Inventor 郑喜群李冠龙刘晓兰邓永平
Owner QIQIHAR UNIVERSITY
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