A controllable extracorporeal infusion balloon for reducing ischemia-reperfusion injury

Abstract

The present invention provides a controllable external input balloon for reducing ischemia-reperfusion injury, which relates to the field of interventional medical devices. It consists of mass pushing tube, proximal flexible tube, balloon, distal flexible tube, guide wire and flow control components. The flow control component consists of an external perfusion joint and a flow controller connected to the external perfusion joint through a catheter; controllable perfusion flow; after the balloon is inflated, the balloon is not released, and the controllable reperfusion balloon is injected in vitro through the external perfusion joint at the distal end of the balloon and the flow controller connected to the external perfusion joint through a catheter To control, the prepared perfusion solution can be used to slowly perfuse the infarct area or the distal end of the ischemic area to avoid ischemia-reperfusion injury; while perfusing the distal end, the balloon only needs to be expanded and released once, which can reduce or avoid vascular injury, Plaque shedding and no-reflow in distal vessels occurred.

Description

technical field [0001] The invention relates to the field of interventional medical devices, in particular to a balloon for reducing ischemia-reperfusion injury used in acute blood vessel occlusion. Background technique [0002] At present, acute vascular occlusive disease is the main cause of death in the Chinese population, including acute myocardial infarction, cerebral infarction, peripheral arterial vascular embolism, etc., patients with acute vascular occlusive disease, the preferred method is emergency interventional treatment to open the infarct-related blood vessels, and then Perfuse the infarcted area; however, in the process of emergency intervention, directly opening the occluded blood vessel will cause further damage, which is called ischemia-reperfusion injury, resulting in further damage to the organs in the infarcted area. [0003] The traditional method of interventional therapy for acute vascular occlusive diseases is to use intravascular guide wires and ba...

AI Technical Summary

Problems solved by technology

However, its design purpose is mainly to exchange guide wires, measure pressure or take blood in coronary arteries. If it is used in the field of acute vascular occlusion, reperfusion injury cannot be avoided, so it is not used in the field of treatment of acute vascular infarction; Improve and innovate on the basis of the above-mentioned technology, and become a controllable ischemia-reperfusion balloon injected in vitro, which can reperfuse the ischemic area in a continuous and uninterrupted way and at the same time deploy the perfusate, so as to reduce the ischemia-reperfusion injury

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