A controllable extracorporeal infusion balloon for reducing ischemia-reperfusion injury

An ischemia-reperfusion and controllable technology, applied in balloon catheters, catheters, etc., to avoid vascular damage and ischemia-reperfusion injury.

Active Publication Date: 2021-07-09
HUNAN PROVINCIAL PEOPLES HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, its design purpose is mainly to exchange guide wires, measure pressure or take blood in coronary arteries. If it is used in the field of acute vascular occlusion, reperfusion injury cannot be avoided, so it is not used in the field of treatment of acute vascular infarction; Improve and innovate on the basis of the above-mentioned technology, and become a controllable ischemia-reperfusion balloon injected in vitro, which can reperfuse the ischemic area in a continuous and uninterrupted way and at the same time deploy the perfusate, so as to reduce the ischemia-reperfusion injury

Method used

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  • A controllable extracorporeal infusion balloon for reducing ischemia-reperfusion injury
  • A controllable extracorporeal infusion balloon for reducing ischemia-reperfusion injury

Examples

Experimental program
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Effect test

Embodiment 1

[0025] see figure 1 , 2 It can be seen that the extracorporeal input controllable balloon for reducing ischemia-reperfusion injury in this embodiment includes a gas inflation interface 1, a hard push tube 2 (a metal push tube is used in this embodiment), a perfusion hose (including a proximal hose 3 and distal hose 6), balloon 5, guide wire 7, and flow control components; the perfusion hose is a double-layer tube structure, and the metal push tube 2 has a first pressure chamber 9 and a part of the perfusion hose. There is a second pressurized chamber 10 inside the inner tube, and the two communicate with each other to form a complete pressurized chamber. The pressurized chamber can be realized based on the metal push tube and the inner wall of the perfusion hose, or can be realized by a separate conduit inside. Such as, the first pressurization chamber just adopts the lumen of metal pushing pipe 2 to realize, and the second pressurization chamber can adopt the lumen between ...

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Abstract

The present invention provides a controllable external input balloon for reducing ischemia-reperfusion injury, which relates to the field of interventional medical devices. It consists of mass pushing tube, proximal flexible tube, balloon, distal flexible tube, guide wire and flow control components. The flow control component consists of an external perfusion joint and a flow controller connected to the external perfusion joint through a catheter; controllable perfusion flow; after the balloon is inflated, the balloon is not released, and the controllable reperfusion balloon is injected in vitro through the external perfusion joint at the distal end of the balloon and the flow controller connected to the external perfusion joint through a catheter To control, the prepared perfusion solution can be used to slowly perfuse the infarct area or the distal end of the ischemic area to avoid ischemia-reperfusion injury; while perfusing the distal end, the balloon only needs to be expanded and released once, which can reduce or avoid vascular injury, Plaque shedding and no-reflow in distal vessels occurred.

Description

technical field [0001] The invention relates to the field of interventional medical devices, in particular to a balloon for reducing ischemia-reperfusion injury used in acute blood vessel occlusion. Background technique [0002] At present, acute vascular occlusive disease is the main cause of death in the Chinese population, including acute myocardial infarction, cerebral infarction, peripheral arterial vascular embolism, etc., patients with acute vascular occlusive disease, the preferred method is emergency interventional treatment to open the infarct-related blood vessels, and then Perfuse the infarcted area; however, in the process of emergency intervention, directly opening the occluded blood vessel will cause further damage, which is called ischemia-reperfusion injury, resulting in further damage to the organs in the infarcted area. [0003] The traditional method of interventional therapy for acute vascular occlusive diseases is to use intravascular guide wires and ba...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61M25/10
CPCA61M25/1025A61M25/104A61M2025/1079A61M25/10181A61M25/10184
Inventor 曹彦谢娇张宇谭波宇陈华丽丘小英王长录何晋刘征宇潘宏伟郑昭芬
Owner HUNAN PROVINCIAL PEOPLES HOSPITAL
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