Oral donkey-hide gelatin preparation and preparation method thereof

A technology of oral preparations and donkey-hide gelatin, which is applied in the field of donkey-hide gelatin oral preparations and its preparation, can solve the problems of donkey-hide gelatin component loss, uneven composition of donkey-hide gelatin, and destruction of donkey-hide gelatin nutrients, and achieve high absorption efficiency

Pending Publication Date: 2018-12-18
湖南药圣堂中药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because donkey-hide gelatin is difficult to dissolve and inconvenient to take, different formulas and different technologies are often used to make different types of donkey-hide gelatin oral preparations according to the population and needs of the users, so as to facilitate people's use and give full play to the medicinal and nutritional value of donkey-hide gelatin, such as oral administration of donkey-hide gelatin to enrich blood Ejiao liquid, donkey-hide gelatin angelica granules, donkey-hide gelatin tablets, donkey-hide gelatin sesame cake and other donkey-hide gelatin oral preparations, but in the manufacturing process, donkey-hide gelatin is difficult to dissolve quickly and fully, and it is also prone to coking and agglomeration in the process of boiling and dissolving with purified water or medicinal liquid. Even long-term burning at high temperature destroys the nutrients in donkey-hide gelatin, and it is difficult to mix evenly with other raw materials or liquid medicines in donkey-hide gelatin oral preparations, resulting in uneven co

Method used

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  • Oral donkey-hide gelatin preparation and preparation method thereof
  • Oral donkey-hide gelatin preparation and preparation method thereof

Examples

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preparation example Construction

[0028] The preparation method of the donkey-hide gelatin oral preparation includes the following steps:

[0029] S1. Mix the superfine powder of donkey-hide gelatin with purified water, ultrasonically treat it for 20-30 minutes, stir continuously during the ultrasonic treatment, and then increase the temperature to pressurize the glue to obtain a melted glue solution, the temperature of which is 70-90°C , The pressure is 0.3-0.4Mpa, and the time for gelatinization is 0.5-1h;

[0030] S2. The rock sugar is melted into a syrup with purified water, precipitated for 2-4h, filtered through a 100-110 mesh sieve, pumped into the melted gum solution obtained from the treated S1, add soybean oil, tea oil and yellow wine and mix well. Stir at 1500-2500r / min for 1-2h to obtain material a;

[0031] S3. Mix Jerusalem artichoke, astragalus, medlar and purified water evenly, soak in 25% ethanol solution for 20-26h, percolate at 2ml / min, and evaporate and concentrate to obtain material b;

[0032] S...

Embodiment 1

[0037] An oral preparation of donkey-hide gelatin, in parts by weight, comprising the following raw materials: 50 parts of donkey-hide gelatin, 32 parts of rock sugar, 26 parts of soybean oil, 3.8 parts of tea oil, 5.7 parts of yellow wine, 9.8 parts of Jerusalem artichoke, 5.7 parts of fish bone meal, 4.6 parts of astragalus, 13.5 parts of wolfberry, 7.4 parts of chitosan, 18.6 parts of sustained-release aids;

[0038] The sustained-release auxiliary agent is prepared according to the following process: 22.3 parts of α-starch, 3.4 parts of sodium glutamate, 4.2 parts of sugar terpenes, 5.8 parts of spirulina, 4.3 parts of decoction, and 5.7 parts of soy eggs are combined by weight. Mix the phospholipids evenly, stir at 520r / min for 24min, then dry in a freeze dryer at -42℃ for 32min, then add 17 parts of polylactic acid and mix well, stir at 5200r / min for 14min, then add 18 parts of ethanol gel and mix well , Then stirred at 285r / min for 4h, then centrifuged at 10500r / min for co...

Embodiment 2

[0047] An oral preparation of donkey-hide gelatin, in parts by weight, comprising the following raw materials: 5 parts of donkey-hide gelatin, 40 parts of rock sugar, 20 parts of soybean oil, 6 parts of tea oil, 4 parts of yellow wine, 15 parts of Jerusalem artichoke, 4 parts of fish bone meal, 6 parts of astragalus, 8 parts of wolfberry, 9 parts of chitosan, 15 parts of sustained-release aids;

[0048] The sustained-release aid is prepared according to the following process: 15 parts by weight of α-starch, 5 parts of sodium glutamate, 3 parts of sugar terpenes, 8 parts of spirulina, 3 parts of decoating, and 8 parts of soy eggs Phospholipids are mixed uniformly, stirred at 350r / min for 30 minutes, then dried in a freeze dryer at -30°C for 40 minutes, then 12 parts of polylactic acid are added and mixed well, stirred at 5500r / min for 10 minutes, and then 20 parts of ethanol gel are added and mixed well , Then stirred at 250r / min for 5h, then centrifuged at 8500r / min for collectio...

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Abstract

The invention discloses an oral donkey-hide gelatin preparation and a preparation method thereof, and belongs to the technical field of production of traditional Chinese medicines. The oral donkey-hide gelatin preparation comprises ultrafine donkey-hide gelatin powder, rock sugar, soybean oil, tea oil, yellow rice wine, Jerusalem artichoke, fish bone meal, Radix Astragali, wolfberry fruits, chitosan and a slow release assistant. The preparation method comprises the following steps: preparing a dissolved gelatin solution, blending the dissolved gelatin solution, extracting effective traditionalChinese medicinal health components from the Jerusalem artichoke, Radix Astragali and wolfberry fruits, adding the chitosan to ensure the clearness of the preparation, adding the fish bone meal to supplement calcium element, and adding the slow release assistant to improve the absorption rate of nutrients in the oral donkey-hide gelatin preparation by using the drug effect slow release effect ofthe slow release assistant. The oral donkey-hide gelatin preparation prepared in the invention has an excellent drug absorption efficiency.

Description

【Technical Field】 [0001] The invention relates to the fields of food, medicine, and health products, in particular to an oral donkey-hide gelatin preparation and a preparation method thereof. 【Background technique】 [0002] Ejiao is a traditional and precious Chinese medicine in my country. It is called the three treasures of traditional Chinese medicine together with ginseng and velvet antler. It has a history of more than 2,000 years. It is a traditional nourishing and blood-enriching top-grade product. It is recorded in ancient pharmacopoeias and pharmacopoeias. It is an equine animal donkey. The dried skin or fresh skin is decocted and concentrated to make solid glue. The nature and flavor are sweet, calm, and belong to the lung, liver and kidney channels. It has the effects of nourishing blood, nourishing yin, moisturizing dryness, and stopping bleeding. It is used for blood deficiency and chlorosis, dizziness, heart palpitations, muscle atrophy, weakness, upset and eyesight...

Claims

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Application Information

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IPC IPC(8): A61K35/36A61K36/82A61K47/36A61K47/18A61K47/34A61P7/06A61P1/08A61P9/06A61P21/00A61P25/20A61P43/00A61P11/00A61P11/14A61P7/04A61P1/00A61P13/00A61P15/00A61P15/06A23L33/00A61K35/60A61K35/748
CPCA61K35/36A61K35/60A61K35/748A61K36/28A61K36/481A61K36/815A61K36/82A61K47/183A61K47/34A61K47/36A61K2236/333A61K2236/51A61K2236/53A23L33/00A61P1/00A61P1/08A61P7/04A61P7/06A61P9/06A61P11/00A61P11/14A61P13/00A61P15/00A61P15/06A61P21/00A61P25/20A61P43/00A61K2300/00
Inventor 钟振平谢雄吴顺丽
Owner 湖南药圣堂中药科技有限公司
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