Method, measuring instrument and system for detecting urine specific gravity

A measuring instrument and technology of urine specific gravity, which is applied in the field of urine detection, can solve the problems of low precision and complicated operation, and achieve the effect of high precision and simple operation

Active Publication Date: 2021-06-29
上海荒岛科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The hospital uses a fully automatic urine analyzer to test urine specific gravity, that is, the test paper method. It is the most commonly used method at present. It is simple to operate but the accuracy is not high (±0.005). The refractive index method is an optical method, which is more common in county hospitals. Gravimetric method Although the precision is high, the operation is complicated, and it is commonly used in laboratories and scientific research institutions.

Method used

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  • Method, measuring instrument and system for detecting urine specific gravity
  • Method, measuring instrument and system for detecting urine specific gravity
  • Method, measuring instrument and system for detecting urine specific gravity

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0099] A system for detecting specific gravity of urine, comprising an electrochemical sensor and a measuring instrument, wherein figure 1 It is a structural schematic diagram of an optional electrochemical sensor. In the figure, 1 is the substrate, 2 is the working electrode, 3 is the counter electrode, 4 is the trigger electrode, 5 is the insulating film, 6 is the reagent layer, 7 is the hydrophilic film, 8 is a double-sided adhesive layer, 9 is a sample guide groove, and 10 is an air outlet;

[0100] The surface of the substrate is screen-printed with electrode shapes, which are L-shaped working electrode 2, L-shaped counter electrode 3 and T-shaped trigger electrode 4, and the trigger electrode 4 is arranged in the space formed by the working electrode 2 and the counter electrode 3;

[0101] The L end side surface of the working electrode 2 is provided with an insulating film 5, and the insulating film 5 is provided with an opening, and the reagent layer 6 is arranged in t...

Embodiment 2

[0111] Detect urine urine specific gravity, adopt the system of embodiment 1, the reagent in the reagent layer in the sensor is as shown in table 1, and table 1 is the composition data table of reagent in the reagent layer of the present embodiment; Obtain the calculation that is set in the measuring instrument thus Formula Y=0.00148*X+0.99922; the values ​​of parameters A and B can be determined through multiple experiments.

[0112] The reagent data sheet of table 1 embodiment 2 reagent layer

[0113] substance mass ratio Potassium ferricyanide 6.45％ Trehalose 1.8％ Hydrophilic silica 0.9％ Tween-20 0.45％ Phosphate buffer solution 45.2％ water 45.2％

[0114] Take 10 urine samples, numbered 1-10 respectively, apply +0.4V voltage to the sensor with a measuring instrument, and test the response current for 30 seconds. The above calculation formula set by the measuring instrument can directly obtain the specific gravity of urine f...

Embodiment 3

[0120] The process of testing the specific gravity of urine is the same as in Example 2, except that the reagent of the sensor reagent layer is as shown in Table 3. The calculation formula in this embodiment is obtained according to the following reagents: Y=0.00183*X+1.00162; The comparison results are shown in Table 4, Figure 5 For the present embodiment urine specific gravity and electrochemical sensor test current fitting linear diagram;

[0121] Table 3 The reagent data sheet of the sensor reagent layer of this embodiment

[0122] substance mass ratio Potassium ferricyanide 4％ Trehalose 3％ Hydrophilic silica 1.5％ Tween-20 0.3％ Phosphate buffer solution 45.6％ water 45.6％

[0123] Table 4 present embodiment obtains urine specific gravity and refractometer test urine specific gravity error data table

[0124] urine sample number Electrode current (μA) Calculate urine specific gravity test urine specific g...

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Abstract

The invention provides a method for detecting the specific gravity of urine, comprising: a measuring instrument applies a voltage to an electrochemical sensor; obtains a response current value generated after the electrochemical sensor interacts with urine; according to the response current value, Calculate urine specific gravity. The present application also provides a measuring instrument for detecting the specific gravity of urine, and the present application also provides a system for detecting the specific gravity of urine. The application uses an electrochemical method to test the specific gravity of urine, which has high precision, required equipment and simple operation.

Description

technical field [0001] The invention relates to the technical field of urine detection, in particular to a method, a measurement system and a system for detecting urine specific gravity. Background technique [0002] Urine routine is a basic routine item for disease detection. Urine specific gravity and urine sugar in urine routine can realize the screening and diagnosis of diseases more intuitively. [0003] Urine specific gravity itself reflects the content of solute in a unit volume of urine, which is the ratio of the weight of water at 4°C to the same volume of water. Solutes in urine mainly include small metabolic molecules such as urea and ions such as potassium, sodium, and chloride. The higher the concentration of metabolites and other components in urine, the greater the specific gravity of urine. Normal adult urine specific gravity is more than 1.015 ~ 1.025. Urine specific gravity reflects the concentrating function of the kidney. High urine specific gravity is...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N9/36
CPCG01N9/36
Inventor 徐晨龙王文冲
Owner 上海荒岛科技有限公司
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