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Oral compsns. contg. dimethicone copolyols

A technology of dimethyl polysiloxane and copolyol, which is applied to the active ingredients of silicon compounds, medical preparations containing active ingredients, and drug combinations, etc.

Inactive Publication Date: 2002-09-18
THE PROCTER & GAMBLE COMPANY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] A typical disadvantage in known dental preparations is that only a relatively short period of time, namely brushing and rinsing, is available for the antiseptic to act
This problem is made more difficult by the fact that dentifrice preparations are used infrequently, most once or twice a day

Method used

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  • Oral compsns. contg. dimethicone copolyols

Examples

Experimental program
Comparison scheme
Effect test

Embodiment I to V

[0081] The following are representative denture cleaning tablets of the present invention. The percentages therein are based on the total weight of the tablet. Tablets are formed by compressing the granulated ingredient mixture in a punch and die tablet press at a pressure of about 105 kPa.

[0082] I II III IV V

[0083] Malic acid 12 10 15 - 14

[0084] Citric acid - 10 - 15 -

[0085] Sodium carbonate 10 8 10 6 10

[0086] Sulfamic acid 5 - - 3 3

[0087] PEG 20,000 - 3 7 8 5

[0088] PVP 40,000 6 3 - - -

[0089] Sodium bicarbonate 22 25.2 25 13.9 23

[0090] Sodium perborate monohydrate 15 12 16 30 15

[0091] Potassium monopersulfate 15 18 13 - 14

[0092] Fumed silica - 0.3 0.1 0.1 -

[0093] Talc 2 - - - -

[0094] EDTA - - 1 - 3

[0095] EDTMP 1 1 - - 1 -

[0096] food flavor 5 2 1 2 1 2

[0097] Abil EM90 4 1 1.5 5 10 1

[0098] Bleach precursor agglomerates ...

Embodiment VI to VIII

[0114] The following are representative toothpaste / denture cleaning pastes of the present invention. The percentages are by weight of the total composition.

[0115] VI VII VIII

[0116] Calcium carbonate 20 25 15

[0117] Glycerol 10 12 8

[0118] Sodium carboxymethylcellulose 3.5 3 4

[0119] Titanium dioxide 0.7 0.5 0.6

[0120] Methyl / Propyl Paraben 0.1 0.1 0.1

[0121] Sodium saccharin 0.3 0.4 0.2

[0122] food flavor 5 1 1 2

[0123] Abil EM90 4 1 1.5 0.5

[0124] Triclosan - 0.5 -

[0125] Water make up to 100%

[0126] The toothpaste / denture cleaning pastes of Examples VI to VIII exhibit improved antiplaque, flavor action and antimicrobial activity as well as excellent dentifrice properties.

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Abstract

An oral composition in the form of a toothpaste, powder, liquid dentifrice, mouthwash, denture cleanser, chewing gum or candy comprising a lipophilic compound selected from flavorants, physiological cooling agents and antimicrobial compounds and a dimethicone copolyol selected from alkyl- and alkoxy-dimethicone copolyols having formula (I) wherein X is selected from hydrogen, alkyl, alkoxy and acyl groups having from about 1 to about 16 carbon atoms, Y is selected from alkyl and alkoxy groups having from about 8 to about 22 carbon atoms, n is from about 0 to about 200, m is from about 1 to about 40, q is from about 1 to about 100, the molecular weight of the residue (C2H4O-)x(C3H6O-)yX is from about 50 to about 2000, and x and y are such that the weight ratio of oxyethylene:oxypropylene is from about 100:0 to about 0:100. The composition provides improved antiplaque and anti-bacterial activity together with enhanced substantivity, impact and / or efficacy of the lipophilic components on teeth or dentures.

Description

technical field [0001] The present invention relates to compositions for oral cavity, such as toothpaste, tooth powder, toothwash, mouthwash, denture cleaner, chewing gum, candy and the like. In particular, the present invention relates to oral compositions having enhanced antiplaque activity and excellent dentifrice, physical properties and general versatility. Background technique [0002] Plaque is caused when bacteria that adhere to the pellicle form a protein film on the tooth surface. Adhesive bacteria metabolize food components and multiply and build up, forming tough deposits called plaque. Dental plaque is generally composed of bacteria, bacterial end products such as polysaccharides, inorganic salts, and salivary proteins. Plaque bacteria ferment carbohydrates in food into organic acids, which demineralize enamel and cause tooth decay. [0003] Calculus are actually dental plaque mineralized with calcium phosphate salts. As the stone ages and hardens, it tends ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K7/16A61K6/093A61K31/695A61P1/02A23G3/34A23G4/00A23L27/00A61K8/00A61K8/22A61K8/24A61K8/25A61K8/26A61K8/33A61K8/34A61K8/35A61K8/36A61K8/368A61K8/38A61K8/42A61K8/89A61K8/894A61K8/898A61K8/97A61Q11/00A61Q11/02C08L83/12
CPCA61K8/22A61K8/347A61K8/894A61K2800/222A61Q11/00A61P1/02
Inventor I·A·休斯
Owner THE PROCTER & GAMBLE COMPANY