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Method for surface desulfurization of medicinal material pinellia ternate

A technology of medicinal materials, pinellia, applied in the field of surface desulfurization of pinellia medicinal materials, which can solve problems such as long soaking time, loss of active ingredients of Chinese medicinal materials, and impact, and achieve the effect of reducing soaking time, ensuring drug efficacy, and good desulfurization effect

Inactive Publication Date: 2019-01-04
CHONGQING MEDICAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the traditional water soaking desulfurization method has the disadvantages of long soaking time and poor desulfurization effect, which makes the active ingredients of Chinese herbal medicines lose and affects their efficacy. Guaranteed the efficacy of Chinese herbal medicines

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] 1 Instruments and reagents:

[0013] KQ2200B Ultrasonic Instrument (Kunshan Ultrasonic Instrument Co., Ltd.); DK-S28 Electric Heating Constant Temperature Water Bath (Shanghai Senxin Experimental Instrument Co., Ltd.); MP2002 Electronic Balance (Shanghai Sunny Hengping Scientific Instrument Co., Ltd.); PHS-3C pH Meter (Shanghai INESA Scientific Instrument Co., Ltd.);

[0014] The pinellia medicinal material was identified as the dry tuber of Pinellia ternata (Thunb.) Breit; the water used in the experiment was tap water with a pH of 6.70.

[0015] 2 Methods and results

[0016] 2.1 Method: Select 15g of pinellia medicinal materials with a diameter of about 1cm in parallel in 3 groups, soak them in 75mL of tap water, put the above-mentioned Chinese medicinal materials in an ultrasonic instrument, set the ultrasonic power to 100w, the temperature to 50°C, and the ultrasonic time to 1h , Take out the Chinese herbal medicines after ultrasonication, drain them, and let the...

Embodiment 2

[0019] 2.1 Method: Select 15g of pinellia medicinal materials with a diameter of about 1cm in parallel in 3 groups, soak them in 75mL of tap water, put the above-mentioned Chinese medicinal materials in an ultrasonic instrument, set the ultrasonic power to 70w, the temperature to 40°C, and the ultrasonic time to 2h , Take out the Chinese herbal medicines after ultrasonication, drain them, and let them dry in the shade at room temperature.

[0020] 2.2 Results: The residual sulfur dioxide in Pinellia without desulfurization treatment was 2150 mg / kg, and the residual sulfur dioxide in the three groups after ultrasonic desulfurization treatment was 89 mg / kg, 100 mg / kg, and 120 mg / kg, with an average value of 103 mg / kg. The results were less than 150mg / kg, which is lower than the prescribed sulfur dioxide residual standard, with a relative standard deviation of 15.2%, and a desulfurization rate of 95.2%.

Embodiment 3

[0022] 2.1 Method: Select 15g of pinellia medicinal materials with a diameter of about 1cm in parallel in 3 groups, soak them in 75mL of tap water, put the above-mentioned Chinese medicinal materials in an ultrasonic instrument, set the ultrasonic power to 40w, the temperature to 60°C, and the ultrasonic time to 3h , Take out the Chinese herbal medicines after ultrasonication, drain them, and let them dry in the shade at room temperature.

[0023] 2.2 Results: The residual sulfur dioxide in Pinellia without desulfurization treatment was 2150 mg / kg, and the residual sulfur dioxide in the three groups after ultrasonic desulfurization treatment was 174 mg / kg, 200 mg / kg, and 267 mg / kg, with an average value of 213 mg / kg, and the results were greater than 150mg / kg, the relative standard deviation is 22.4%, and the desulfurization rate is 90.1%.

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Abstract

The invention discloses a method for surface desulfurization of the medicinal material pinellia ternate. The method includes the steps that the medicinal material pinellia ternate with the diameter being 1 cm or so is selected, wherein the mass ratio of the traditional Chinese medicinal material to water is 1:5; the medicinal material pinellia ternate is put into an ultrasonic instrument, whereinthe ultrasonic power is set to be 100 w, the temperature is set to be 50 DEG C, and the ultrasonic time is 1 h; the ultrasonically-treated medicinal material pinellia ternate is taken out, drained andplaced under the room temperature to be dried in the shade. The method overcomes the defect of long soaking time in a traditional water soaking desulfurization process, reduces the loss of active ingredients in the traditional Chinese medicinal material under desulfurization of the traditional Chinese medicinal material and effectively guarantees the medicinal effect of the medicinal material; besides, the method is easy to implement and low in cost and has the use and promotion value.

Description

technical field [0001] The invention relates to the technical field of processing traditional Chinese medicinal materials, in particular to a method for surface desulfurization of Pinellia medicinal materials. Background technique [0002] Pinellia is the dry tuber of Pinellia ternata (thunb.) Breit., a plant of the family Araceae. It is pungent and warm in nature. It has the effects of drying dampness and resolving phlegm, reducing adverse reactions and relieving vomiting, and eliminating mass. It is clinically used for phlegm, cough and asthma. , Wind-phlegm dizziness, vomiting and nausea, chest and abdominal fullness embolism, etc., have many clinical applications. Taking Chinese herbal medicines with sulfur dioxide exceeding the standard will cause nausea, vomiting and other gastrointestinal reactions and affect the absorption of calcium in mild cases. Substance - Nitrosamines. Therefore, it is necessary to take certain desulfurization means to control the sulfur dioxi...

Claims

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Application Information

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IPC IPC(8): A61K36/8888A61K125/00
CPCA61K36/8888A61K2236/10
Inventor 何丹青旺旺张景勍
Owner CHONGQING MEDICAL UNIVERSITY