Food composition comprising jerusalem artichoke and konjac extract as well as preparation method thereof and application

A technology of extracts and compositions, which is applied to food compositions containing Jerusalem artichoke and konjac extracts and its preparation and application fields, can solve the problems of lack of in-depth research and combination, and achieve the adjustment of lipid metabolism disorders, reduction of drinking water, Blood sugar lowering effect

Inactive Publication Date: 2019-01-25
王丹巧 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] In these prior art foods, mainly utilize the respective nutrition of Jerusalem artichoke and konjac or the function of lo...

Method used

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  • Food composition comprising jerusalem artichoke and konjac extract as well as preparation method thereof and application
  • Food composition comprising jerusalem artichoke and konjac extract as well as preparation method thereof and application
  • Food composition comprising jerusalem artichoke and konjac extract as well as preparation method thereof and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] Example 1. Intervention effect of food composition comprising Jerusalem artichoke and konjac extract on STZ-induced diabetic rats

[0046] 1. Experimental modeling, grouping and administration:

[0047] Streptozotocin (STZ) was purchased from Sigma Company in the United States; blood glucose monitors and blood glucose kits were purchased from Roche Diagnostics Co., Ltd., Germany; healthy normal male SD rats, weighing 180-200 g, were purchased from Beijing Weitong Lihua Laboratory Animal Technologies Ltd.

[0048] 100 male SD rats were purchased and fed adaptively for 3 days, fasted for 12 hours, blood was collected from the tail vein, and the blood glucose level was measured. SD rats with normal fasting blood glucose were selected for the experiment. Except for 10 rats injected with equal volume of citric acid buffer as the control group, the rest of the rats were intraperitoneally injected with 1% STZ 60 mg / kg (STZ was prepared with 0.1 mol / L citric acid buffer). Aft...

Embodiment 2

[0060] Example 2. Study on the Superiority of Intervention Effects of Food Compositions Containing Jerusalem artichoke and Konjac Extracts on Diabetic Rats Induced by STZ

[0061] 1. Research Methods

[0062] Streptozotocin (STZ) induced diabetic rat model and the criteria for screening and judging the success of the model were the same as in Example 1.

[0063] Grouping and administration: 10 normal rats were selected as the normal control group, and 50 rats with successful modeling were selected for subsequent experiments, and were randomly divided into 5 groups, 10 rats in each group. They were model group, metformin group (120mg / kg), inulin group (3% inulin water), konjac group (1.2g / kg), inulin + konjac group (3% inulin water + konjac 1.2g / kg). Administration for 4 weeks, the specific administration method of the administration group is as follows in Table 2.

[0064] Table 2

[0065]

[0066] During the administration period, the state of the rats was observed dail...

Embodiment 3

[0075] Example 3, the intervention effect of food composition comprising Jerusalem artichoke and konjac extract on spontaneous type 2 diabetes BKS.DB mice

[0076] 1. Experimental method:

[0077] BKS-DB mice, that is, db / db (C57BL / KsJ) mice, are congenital type 2 diabetic mice caused by Leptin receptor gene defect. Gluttony and obesity appear from the age of four weeks. Obvious characteristics such as hyperglycemia, hyperlipidemia, and insulin resistance appear as the age increases, and its pathogenesis is very similar to that of patients with type 2 diabetes. It is an ideal animal model for experimental research on type 2 diabetes. In this experiment, 50 BKS-DB mice (4 weeks old) and 10 db / m mice were purchased. After 1 week of pre-adaptation, the BKS-DB mouse model group, metformin group (150mg / kg), inulin group (3% inulin syrup), konjac group (1.2g / kg), inulin+konjac group (3% Inulin water + konjac 1.2g / kg). Ten db / m mice served as the normal control group. Dosing for ...

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Abstract

The invention provides a food composition comprising jerusalem artichoke and konjac extract as well as a preparation method thereof and application, and particularly relates to application of the foodcomposition comprising jerusalem artichoke and konjac extract in preparing food with effect of treating diabetes in an adjuvant mode. The food composition comprising jerusalem artichoke and konjac extract comprises jerusalem artichoke extract and konjac extract; and in terms of weight of synanthrin contained in the jerusalem artichoke extract and glucomannan contained in the konjac extract, a weight ratio of jerusalem artichoke extract to konjac extract is (1-10) to (1-10). The food composition comprising jerusalem artichoke and konjac extract has a cooperative effect on reducing blood glucose and/or reducing body weight.

Description

technical field [0001] The present invention relates to a food composition comprising extracts of Jerusalem artichoke and konjac and its preparation method and application, in particular to the application of the food composition comprising extracts of Jerusalem artichoke and konjac in the preparation of food with the effect of assisting the treatment of diabetes . Background technique [0002] Jerusalem artichoke (Jerusalem artichoke), also known as Jerusalem artichoke, is a perennial herbaceous plant of the genus Sunflower in the family Asteraceae. The fresh tubers of Jerusalem artichoke are edible, rich in Jerusalem artichoke inulin, accounting for about 10% to 20%, which is a fructose polymer. Jerusalem artichoke inulin is a soluble dietary fiber with an insulin-like structure, a proliferation factor of bifidobacteria and lactic acid bacteria in the body, lowers blood lipids and blood sugar, has a certain auxiliary effect on diabetes, and has the characteristics of low ...

Claims

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Application Information

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IPC IPC(8): A23L33/105
CPCA23L33/105A23V2002/00
Inventor 王丹巧高同强高天乐白戈张迪欧
Owner 王丹巧
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