Method for preparing micro-nano oriented fiber with controllable rigidity

A micro-nano, oriented technology, applied in fiber processing, conjugated synthetic polymer rayon, filament/thread forming, etc., can solve problems such as chemical composition changes, and achieve the effect of expanding scope and low cost

Active Publication Date: 2019-02-01
DONGHUA UNIV
View PDF8 Cites 11 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The technical problem to be solved by the present invention is to provide a method for preparing micro-nano-scale oriented fibers with controllable stiffness, so as to overc

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method for preparing micro-nano oriented fiber with controllable rigidity
  • Method for preparing micro-nano oriented fiber with controllable rigidity
  • Method for preparing micro-nano oriented fiber with controllable rigidity

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0048] (1) At room temperature, 0.684g PLCL (the copolymerization ratio of lactic acid and caprolactone is 50:50, the viscosity is 2.5dl / g, purchased from Jinan Daigang Biomaterials Co., Ltd.), 0.036g ultra-high molecular weight PEO ( Molecular weight>5.0×10 6 Da (purchased from Alfa Aesar, UK) was dissolved in 6mL of hexafluoroisopropanol (purchased from Shanghai Darui Fine Chemicals Co., Ltd.), and stirred for 12 hours to obtain PLCL- PEO shell solution.

[0049] (2) 0.57g PLLA (molecular weight of polylactic acid is 100,000Da, purchased from Jinan Daigang Biomaterials Co., Ltd.), 0.03g ultra-high molecular weight PEO (molecular weight>5.0×10 6 Da (purchased from Alfa Aesar, UK) was dissolved in 6 mL of hexafluoroisopropanol (purchased from Shanghai Darui Fine Chemicals Co., Ltd.), and stirred for 12 hours to obtain PLLA- PEO core solution.

[0050] (3) The shell solution and the core solution prepared above are respectively placed in separate syringes, such as figure 1...

Embodiment 2

[0057] The injection rate of PLCL shell solution was 0.35mL / h and the injection rate of PLLA core solution was 0.15mL / h during stable jet coaxial electrospinning, and the rest were the same as in Example 1 to obtain PLCL / PLLA micro-nano-scale oriented fibers.

[0058] Figure 5 It shows that the PLCL / PLLA micro-nano-scale oriented fiber has a highly oriented structure, and the fiber diameter is 1.40±0.16 μm, which is not significantly different from the fiber diameter obtained in Example 1, that is, the fiber diameter does not change significantly after the shell-core structure is adjusted. .

[0059] Image 6 It shows that PLCL / PLLA micro-nano-scale oriented fiber has obvious shell-core structure, and the chemical composition of the fiber surface does not change, which is still PLCL. The thickness of PLCL shell layer is measured to be 0.35±0.06 μm.

[0060] Figure 11 It shows that the fiber obtained in this example has a higher degree of orientation, and the degree of ori...

Embodiment 3

[0064] The injection rate of PLCL shell solution was 0.2mL / h, and the injection rate of PLLA core solution was 0.3mL / h during steady-jet coaxial electrospinning. The rest were the same as in Example 1 to obtain PLCL / PLLA micro-nano-scale oriented fibers.

[0065] Figure 7 It shows that the PLCL / PLLA micro-nano-scale oriented fiber has a highly oriented structure, and the fiber diameter is 1.34±0.20 μm, which is not significantly different from the fiber diameter obtained in Example 1-2, that is, the fiber diameter does not significantly change after the shell-core structure is adjusted. Sexual changes.

[0066] Figure 8 It shows that PLCL / PLLA micro-nano-scale oriented fiber has obvious shell-core structure, and the chemical composition of the fiber surface does not change, which is still PLCL. The thickness of PLCL shell layer is measured to be 0.16±0.02μm.

[0067] Figure 11 It shows that the fiber obtained in this example has a higher degree of orientation, and the de...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
Diameteraaaaaaaaaa
Elastic modulusaaaaaaaaaa
Young's modulusaaaaaaaaaa
Login to view more

Abstract

The invention relates to a method for preparing a micro-nano oriented fiber with a controllable rigidity. The method comprises the following steps: preparing a spinning solution for a shell layer, preparing a spinning solution for a core layer, and preparing the micro-nano oriented fiber with the controllable rigidity. The micro-nano oriented fiber prepared by the method has a highly-oriented structure, and the thickness of the shell/core can be regulated based on the characteristics of a shell-core structure to regulate the rigidity of the fiber without changing the integral structure or thesurface chemical properties of the fiber.

Description

technical field [0001] The invention belongs to the field of preparation of electrospun fibers, in particular to a method for preparing micro-nano level oriented fibers with controllable stiffness. Background technique [0002] The micro-nanofibers prepared by electrospinning are considered to be an important class of scaffold construction materials that can promote the repair and regeneration of damaged tissues because of their characteristics similar to the structure of the extracellular matrix of natural human tissues. Especially for tissues with specific structures (such as blood vessels, tendons, ligaments, and nerves), highly oriented micro-nanofibers have potential application prospects. However, in tissue engineering, although such oriented fibers can induce cells to form cell shapes similar to natural tissues, scaffold stiffness has also been proven to be an important scaffold parameter for regulating cell fate and guiding tissue regeneration, which determines the s...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): D01F8/14D01F8/06D01D5/34D01D5/00
CPCD01D5/003D01D5/0069D01D5/0076D01D5/0092D01D5/34D01F8/06D01F8/14
Inventor 张彦中易兵成沈炎冰唐寒王先流
Owner DONGHUA UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap