Method for detecting chlortetracycline by fluorescent carbon dots prepared by using p-phenylenediamine and acetic acid as carbon source

Abstract

The invention discloses a method for detecting chlortetracycline by fluorescent carbon dots prepared by using p-phenylenediamine and acetic acid as carbon sources. An orange-red fluorescent carbon dotsolution is synthesized under the heating condition of a solvothermal reaction kettle by using p-phenylenediamine and acetic acid as carbon sources and ethanol as a dispersion system. The synthesizedcarbon dots have fluorescence characteristics with a maximum excitation wavelength of 527 nm and a maximum emission wavelength of 576 nm. After the reaction of the carbon dot solution with differentconcentrations of chlortetracycline solution, the fluorescence intensity value of the fluorescent carbon dot solution and the chlortetracycline concentration shows a good linear relationship (I<F> -I<F0>) / I<F0>=2.9257x10<6> c+0.3473, wherein I<F> is the fluorescence intensity value, c is the chlortetracycline concentration. The range of chlortetracycline concentration of detectable solutions is 1.0x10<-8>-1.0x10<-5>mol L<-1>, and the detection limit is: 1.5x10<-9>mol L<-1>. The method for detecting chlortetracycline by fluorescent carbon dots prepared by using p-phenylenediamine and acetic acid as carbon sources of the invention has simple process, can rapidly prepare fluorescent carbon dots, and can accurately measure the chlortetracycline concentration of the solution. According to the linear relationship, three synthetic samples are measured, and the measured recovery rate is 97.10%-99.20%, indicating that the method has good practical application value.

Description

technical field [0001] The invention belongs to the technical field of chemical application, and in particular relates to a method for preparing fluorescent carbon dots to detect aureomycin by using p-phenylenediamine and acetic acid as carbon sources. Background technique [0002] Carbon dots (CDs) are a new type of fluorescent nanomaterials. The shape of carbon dots is spherical and granular, and the size is generally within 10 nm. The chemical composition is mainly composed of four elements: C, H, O and N. . Carbon dots have many excellent properties: such as: high luminous efficiency, good stability, rich raw materials, small particle size, low molecular weight, good biocompatibility, low toxicity, rich groups on the surface, easy to mix with drugs, etc. Molecular combination is a good biomedical carrier. However, the carbon dots prepared at this stage still have some shortcomings. For example, wavelength regulation is difficult to achieve. Most of the reported emiss...

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Problems solved by technology

However, the carbon dots prepared at this stage still have some shortcomings

For example, wavelength regulation is difficult to achieve

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