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A kind of medicine for treating primary dysmenorrhea and its application

A primary dysmenorrhea and treatment drug technology, applied in the field of medicine, can solve the problems of no research reports and achieve high safety, improved analgesic effect, and good analgesic effect

Active Publication Date: 2020-11-03
王剑
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The analgesic activity of baicalin has been reported. Although eriocitrin and eriodictyol-7-O-glucoside have been reported to have anti-oxidation, anti-inflammatory, anti-tumor and many other activities, whether they have analgesic activity is currently unknown. Still no studies reported

Method used

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  • A kind of medicine for treating primary dysmenorrhea and its application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] Example 1 Paeoniflorin capsules

[0048] Party:

[0049] Paeoniflorin 1500g

[0050] Sodium starch glycolate 200g

[0051] Preparation:

[0052] Take the prescription amount of paeoniflorin and carboxymethyl starch sodium through an 80-mesh sieve, mix them evenly, and divide them into 10,000 capsules.

Embodiment 2

[0053] Example 2 Paeoniflorin and E. glycoside compound capsules

[0054] Party:

[0055] Paeoniflorin 1312.5g

[0056] Eriotoxin 600g

[0057] Sodium starch glycolate 240g

[0058] Preparation:

[0059] Take the prescription amount of paeoniflorin, eriotrine, and sodium starch glycolate through an 80 mesh sieve, mix them evenly, and divide them into 10,000 capsules.

Embodiment 3

[0060] Example 3 Paeoniflorin and Elycohol-7-O-glucoside compound capsules

[0061] Party:

[0062] Paeoniflorin 1200g

[0063] Elycohol-7-O-glucoside 576g

[0064] Sodium starch glycolate 240g

[0065] Preparation:

[0066] Take the prescription amount of paeoniflorin, saccharol-7-O-glucoside, and sodium starch glycolate, pass through an 80-mesh sieve, mix them evenly, and divide them into 10,000 capsules.

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Abstract

The invention belongs to the field of medicine, and particularly relates to medicine for treating primary dysmenorrhea and a purpose thereof. The medicine for treating primary dysmenorrhea is preparedfrom natural active ingredients in traditional Chinese medicine. The active ingredients at least contain paeoniflorin, and further can also contain at least one of materials from eriocitrin or eriodictyol-7-O-glucoside, wherein the optimized active ingredients are paeoniflorin and eriocitrin. The dosage form of the medicine for treating primary dysmenorrhea is preferably an oral preparation, particularly oral solid dosage forms such as oral tablets and capsules. The medicine for treating primary dysmenorrhea is prepared from 20 to 40 weight parts of paeoniflorin and 11 to 17 weight parts of eriocitrin through being metered in parts by weight. The medicine has a good analgesic effect on the primary dysmenorrhea through an animal model; application prospects used as primary dysmenorrhea treatment medicine are realized.

Description

Technical field [0001] The invention belongs to the field of medicine, and specifically relates to a medicine for treating primary dysmenorrhea and its use. Background technique [0002] Dysmenorrhea is a symptom of abdominal pain in women during menstruation. According to the cause of dysmenorrhea, it can be divided into primary dysmenorrhea and secondary dysmenorrhea. Among them, secondary dysmenorrhea is often caused by menstrual pain caused by other diseases, such as endometriosis, adenomyosis, chronic pelvic inflammatory disease, uterine malformations, etc., which can all cause menstrual pain. For the treatment of secondary dysmenorrhea, symptomatic treatment of the primary disease is needed to relieve menstrual pain. Primary dysmenorrhea often has no obvious organic disease, nor is it accompanied by other gynecological diseases that may cause dysmenorrhea. The typical symptoms of women with primary dysmenorrhea are paroxysmal or persistent severe abdominal pain, backache,...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/7048A61P15/00A61P29/00
CPCA61K9/0053A61K31/7048A61P15/00A61P29/00A61K2300/00
Inventor 王健尹志明管晓燕
Owner 王剑