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Portable colloidal gold test strip photo-thermal detecting device with automatic temperature control and dual channels

A colloidal gold test strip and automatic temperature control technology, applied in the field of analysis and detection, can solve the problems of detection accuracy and sensitivity constraints, interference of ambient temperature, complex data processing, etc., to improve detection accuracy and sensitivity, eliminate negative effects, and data processing. simple effect

Pending Publication Date: 2019-04-02
SHANDONG NORMAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, there are still some defects and deficiencies in the above-mentioned photothermal detection device based on infrared temperature sensor detection
First, the core detection physical quantity of photothermal detection is the temperature value, which is easily disturbed by the ambient temperature, and the variable ambient temperature affects its detection accuracy
The second is that the blank control of the colloidal gold test strip also has a background temperature under laser irradiation, and this background temperature needs to be deducted. However, the current method uses a two-step method to detect the test sample and the blank control. On the one hand, this method will lead to cumbersome detection steps. , the data processing is complicated, which is not conducive to the development of its equipment automation; on the other hand, due to the difference in the detection environment temperature and the thermal balance of the detection device during the two-step detection process, the measured values ​​of the test sample and the blank control drift greatly, and its detection accuracy and sensitivity are affected. Great constraints

Method used

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  • Portable colloidal gold test strip photo-thermal detecting device with automatic temperature control and dual channels
  • Portable colloidal gold test strip photo-thermal detecting device with automatic temperature control and dual channels
  • Portable colloidal gold test strip photo-thermal detecting device with automatic temperature control and dual channels

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Embodiment 1

[0043] like figure 1 As shown, a dual-channel portable colloidal gold test strip photothermal detection device with automatic temperature control includes a housing 13, a controller 12, a dual-channel detection module and an automatic temperature control module. The dual-channel detection module is located inside the casing 13 , and the controller 12 and the automatic temperature control module are installed on the casing 13 .

[0044] The dual-channel detection module includes: a photothermal detection component of a detection group and a photothermal detection component of a control group arranged adjacently.

[0045] The photothermal detection assembly of the detection group includes: a test sample colloidal gold test strip 1, a first infrared temperature sensor 3, and a first laser generator 5, and the first infrared temperature sensor 3 and the first laser generator 5 are all set Above the detection sample colloidal gold test paper strip 1, and the sensing window of the ...

experiment example 1

[0052] Adopt the photothermal detection device described in embodiment 1 to carry out performance test experiment, the 532nm laser that described first laser generator 5, the second laser generator 6 sends is irradiated to the colloidal gold detection zone on the colloidal gold test strip, Colloidal gold absorbs light energy to induce infrared radiation, and the infrared temperature sensor converts the infrared radiation in the detection area into a single temperature value. According to the detection temperature difference between the test sample colloidal gold test strip 1 and the blank control sample colloidal gold test strip The standard curve between the sample concentration and the sample concentration is used to determine the sample concentration of the test sample. During the detection process, the photothermal detection device always maintains the temperature of the detection area at the set temperature (20±1° C.) according to the change of the ambient temperature, rea...

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Abstract

The invention belongs to the technical field of analysis and detection, and in particular relates to a portable colloidal gold test strip photo-thermal detecting device with automatic temperature control and dual channels. The device includes a housing, a controller, a dual channel detection module and an automatic temperature control module. The dual channel detection module is composed of two sets of symmetrically distributed photothermal detection component, each set of the photothermal detection component includes a colloidal gold test strip, a laser generator and an infrared radiation temperature sensor. The automatic temperature control module includes a temperature sensor, a heater and a semiconductor cooling assembly. The controller controls the dual channel detection module and the temperature control module. The device realizes simultaneous detection of a test sample of the colloidal gold test strip and a blank control sample of the colloidal gold test strip by using dual channel, and realizes constant temperature control of the detection environment. Compared with the conventional photothermal detection using a single-channel temperature sensor, the detection result is more sensitive and reliable, and the operation and the processing are simpler.

Description

technical field [0001] The invention belongs to the technical field of analysis and detection, and in particular relates to a dual-channel portable colloidal gold test strip photothermal detection device with automatic temperature control for quantitative analysis of colloidal gold test strips. Background technique [0002] Colloidal gold test strip detection method is a convenient and fast detection method, which has the advantages of wide detection range, simple operation, low cost, and easy to carry. It can be stored for a long time under appropriate conditions. It is not only suitable for grassroots use, but also widely used It is widely used in the fields of food inspection, hospital clinical and animal disease diagnosis. [0003] Colloidal gold test strips generally display the test results visually through the color change of colloidal gold on the test line on the test strip, and the qualitative test results can be obtained by visual inspection. However, the inability...

Claims

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Application Information

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IPC IPC(8): G01N21/17
CPCG01N21/171G01N2021/1714
Inventor 韩笑郭一诺苏树朋张鸿雁聂艳斌瞿郅力孟孜殷松王淑文扈可心
Owner SHANDONG NORMAL UNIV
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