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Preparation method of fresh ginger formula particles

A technology of formula granules and ginger, which is applied in the field of preparation of ginger formula granules to achieve the effects of preventing degradation, improving product quality and preventing changes

Pending Publication Date: 2019-04-05
GUANGDONG YIFANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no report on the preparation of ginger formula granules by continuous dynamic countercurrent extraction process

Method used

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  • Preparation method of fresh ginger formula particles

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] A preparation method for ginger formula granules, comprising the steps of:

[0039] a. Remove impurities from the ginger medicinal material, wash it, and crush it into 0.4cm to obtain ginger decoction pieces;

[0040] b. Continuously input the crushed ginger decoction pieces into the extracting tube of the spiral continuous countercurrent extractor (two-stage 10-section tube structure) through the feeding port at the front end, and the material is continuously forwarded through a set of spiral structures in the extracting tube Push it to the slag outlet of the extraction tube to discharge the slag, and continuously add 16 times the amount of 95°C hot water at the end of each level of extraction tube for continuous countercurrent extraction for 0.5h, and the hot water and the material flow in reverse to the front end of each level of extraction tube The liquid is discharged, the extract is collected, and the ginger dregs are squeezed to recover part of the liquid and the...

Embodiment 2

[0045] A preparation method for ginger formula granules, comprising the steps of:

[0046] a. Remove impurities from the ginger medicinal material, wash it, and crush it into 0.4cm to obtain ginger decoction pieces;

[0047] b. Continuously input the crushed ginger decoction pieces into the extracting tube of the spiral continuous countercurrent extractor (two-stage 10-section tube structure) through the feeding port at the front end, and the material is continuously forwarded through a set of spiral structures in the extracting tube Push it to the slag outlet of the extraction tube to discharge the slag, and continuously add 16 times the amount of 95°C hot water at the end of each level of extraction tube for continuous countercurrent extraction for 0.5h, and the hot water and the material flow in reverse to the front end of each level of extraction tube The liquid is discharged, the extract is collected, and the ginger dregs are squeezed to recover part of the liquid and the...

Embodiment 3

[0052] A preparation method for ginger formula granules, comprising the steps of:

[0053] a. Remove impurities from the ginger medicinal material, wash it, and crush it into 0.4cm to obtain ginger decoction pieces;

[0054] b. Continuously input the crushed ginger decoction pieces into the extracting tube of the spiral continuous countercurrent extractor (two-stage 10-section tube structure) through the feeding port at the front end, and the material is continuously forwarded through a set of spiral structures in the extracting tube Push it to the slag outlet of the extraction tube to discharge the slag, and continuously add 14 times the amount of 80°C hot water at the end of each level of extraction tube for continuous countercurrent extraction for 0.5h, and the hot water and the material flow in reverse to the front end of each level of extraction tube The liquid is discharged, the extract is collected, and the ginger dregs are squeezed to recover part of the liquid and the...

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Abstract

The invention discloses a preparation method of fresh ginger formula particles. The preparation method comprises the steps that a, fresh ginger is subjected to impurity removing, cleaned, crushed or chopped, and thus fresh ginger decoction pieces are obtained; b, the fresh ginger decoction pieces are continuously input into a continuous dynamic countercurrent extracting machine, hot water is addedreversely for continuous dynamic countercurrent extracting, and an extracting solution is collected; c, the extracting solution is filtered, superhigh-temperature instantaneous sterilization is conducted, and filtrate is subjected to decompression concentration into clear paste; d, auxiliary materials are added into the clear paste for dissolving, and spray drying is conducted to obtain dry extract powder; and e, preparation auxiliary materials are added into the dry extract powder, and dry granulation is conducted to obtain the fresh ginger formula particles. According to the preparation method of the fresh ginger formula particles, continuous countercurrent extracting, superhigh-temperature instantaneous sterilization, decompression concentration, spray drying and dry granulation production technologies are adopted, all technological parameters are researched, thus the content of effective components in the fresh ginger formula particles can reach the high level continuously and stably, it is guaranteed that the active component transfer rate is consistent with the active component transfer rate of fresh ginger standard decoction, and the product quality of the fresh ginger formula particles is improved.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine formula granules, in particular to a preparation method of ginger formula granules. Background technique [0002] Zingiber officinale Zingiber officinale The fresh rhizome of Rosc., recorded in the 2015 edition of "Chinese Pharmacopoeia", is a commonly used variety for both medicine and food. It is mild in nature and pungent in taste. For anemofrigid cold, stomach cold vomiting, cold phlegm cough, fish and crab poisoning. [0003] The chemical components of ginger are mainly volatile oil, gingerol and diphenylheptane compounds, among which gingerol is the spicy component in ginger, and it is also a unique component in Zingiberaceae, mainly 6-gingerol, 8 -Gingerol, 6-gingerol, of which 6-gingerol has the highest content, accounting for more than half of the total of the three, which can inhibit platelet aggregation, scavenge free radicals, anti-inflammatory, analgesic, enhan...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61K9/16
CPCA61K9/1652A61K9/1682A61K36/9068A61K2236/15A61K2236/331A61K2236/51
Inventor 魏梅程学仁严玉晶干丽刘远俊龙晶张志鹏崔婷蔡盛康
Owner GUANGDONG YIFANG PHARMA
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