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Preparation of device for repairing and fixing chin bones

A fixation device and bone repair technology, applied in fixers, internal fixators, internal bone synthesis, etc., can solve problems affecting the use of materials

Inactive Publication Date: 2019-04-30
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Through years of clinical use, it has been found that in addition to the above-mentioned advantages, this type of polymer also has some biocompatibility problems described above, thus affecting the use of this material

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] Use magnesium-zinc-calcium alloy to produce plates with length, width, and height of 40mm, 6mm, and 1mm by machining, and have holes with a diameter of 2mm, and then use magnesium-zinc-calcium alloy to make screws with a length of 4mm and a diameter of 2mm. The manufactured boards and screws are cleaned and then dried for use. Take 5g of L-polylactic acid with a molecular weight of 12KDa and dissolve it in 100ml of dichloromethane. After stirring evenly, slowly dissolve 0.5g of magnesium oxide in the solution, and ultrasonically distribute the magnesium oxide in the solution evenly. After weighing the finished plate and screw made of magnesium-zinc-calcium alloy, soak in the polylactic acid solution mixed with magnesium oxide for 5 to 10 minutes, then lift and air-dry, and then soak in the solution again after drying until the final weight is 5% of the weight ends soaking, and finally washes with ethanol for 3 times, and drys and packs and irradiates and sterilizes to c...

Embodiment 2

[0017] Use pure magnesium to produce plates with a length, width, and height of 80mm, 80mm, and 1mm, and holes with a diameter of 2mm, and then use pure magnesium to make screws with a length of 4mm and a diameter of 2mm. The manufactured boards and screws are cleaned and then dried for use. Take 5g of L-polylactic acid with a molecular weight of 22KDa and dissolve it in 100ml of chloroform. After stirring evenly, slowly dissolve 0.25g of magnesium carbonate in the solution, and ultrasonically distribute the magnesium carbonate in the solution evenly. After weighing the boards and screws that have been processed with pure magnesium, soak them in the polylactic acid solution mixed with magnesium carbonate for 20-30 minutes, then pull and air-dry them, and soak them in the solution again after drying until the final weight is equal to that of the original boards or screws. After the weight is 10%, the immersion is finished, and finally, the ethanol is used to wash 3 times, and t...

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PUM

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Abstract

The invention discloses a device for repairing and fixing chin bones, wherein the device is constructed by wrapping parts made of a degradable magnesium-based metal with a composite macromolecular material, belongs to the field of biodegradable materials, and mainly solves the shortcomings of poor biocompatibility and non-degradability of repairing and fixing chin bone materials requiring secondary surgical removal in clinical use. The device used for repairing and fixing chin bones and having good biocompatibility and adjustable degradation time is prepared by wrapping the surface of the magnesium-based metal parts with the composite macromolecular material by a solution pulling and air-drying method.

Description

technical field [0001] The invention relates to a device for repairing and fixing the mandible composed of parts made of degradable magnesium-based metals coated with composite polymer materials. It belongs to the field of biodegradable materials. Background technique [0002] At present, the chin repair and fixation devices used in clinical practice are basically composed of metal materials or polymer materials. The metal materials used are all non-degradable materials, most of which are made of magnesium-based metals. The chin repair fixation device made of polymeric polymer materials is generally made of polyether ether ketone or polylactic acid, wherein polyether ether ketone is non-degradable, and polylactic acid is degradable. Judging from the current clinical use of products made of these two materials, they can basically meet the clinical requirements, but there are also some limitations and potential problems. For example, for the repair of children's chin, becau...

Claims

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Application Information

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IPC IPC(8): A61L31/10A61L31/02A61L31/14A61B17/68
CPCA61L31/10A61B17/68A61L31/022A61L31/148A61L2420/04C08L67/04
Inventor 关茜茹
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