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Pharmaceutical composition for treating myocardial hypoxia-reoxygenation injury and its preparation method and application

A technology of myocardial hypoxia and composition, applied in the field of preparation of the pharmaceutical composition, capable of solving problems such as myocardial ischemia-reperfusion injury

Active Publication Date: 2021-05-07
MINZU UNIVERSITY OF CHINA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the main treatment methods for myocardial infarction are thrombolysis, percutaneous transluminal coronary angioplasty and coronary artery bypass grafting, these methods are likely to cause myocardial ischemia-reperfusion injury

Method used

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  • Pharmaceutical composition for treating myocardial hypoxia-reoxygenation injury and its preparation method and application
  • Pharmaceutical composition for treating myocardial hypoxia-reoxygenation injury and its preparation method and application
  • Pharmaceutical composition for treating myocardial hypoxia-reoxygenation injury and its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028]According to a weight of mass, 12.5 parts of 荭, 40 parts of quercetin and 20 parts of 荆 荆, are mixed, and the pharmaceutical composition is obtained.

Embodiment 2

[0030]According to a mass sheet, 9 copierosides, 48 ​​parts of quercetin and 15.5 parts of whose 荆 荆, were mixed, and the pharmaceutical composition was obtained.

Embodiment 3

[0032]According to a mass sheet, 13 parts of 荭, 39.5 parts of quercetin were mixed and uniform, and the pharmaceutical composition was prepared.

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PUM

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Abstract

The invention discloses a pharmaceutical composition for treating myocardial hypoxia and reoxygenation injury, a preparation method and application thereof. The pharmaceutical composition is prepared from raw materials comprising the following components in parts by weight: 8-17 parts of orientin, 25-53 parts of quercitrin and 13-25 parts of vitexin. The pharmaceutical composition of the present invention can treat myocardial hypoxia-reoxygenation injury with remarkable effect.

Description

Technical field[0001]The present invention relates to a pharmaceutical composition for treating myocardial deficiency recoverable injury, and also relates to the preparation method and use of the pharmaceutical composition.Background technique[0002]With the rapid development of the economy, people's diet and living habits have changed. As a cardiovascular disease that seriously threatens human health, coronary heart disease has rapidly rising in my country's incidence and mortality, and has become an important disease that seriously threatens people's health, with one of the important types of coronary heart disease. At present, the main treatment of myocardial infarction is to thrombolytic, transdermal angioplasty and coronary pulley, which are prone to myocardial ischemia / reperfusion injury. Myocardial ischemia reperfusion injury refers to the heart function, metabolism, and structural injury of ischemic myocardium during the open cycle reperfusion period after a certain period ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/7048A61K31/352A61P9/00A61P9/10
Inventor 黄秀兰李志勇万思琦
Owner MINZU UNIVERSITY OF CHINA