Pretreatment device for miniature two-dimensional chromatograph and working method thereof

Abstract

The invention discloses a pretreatment device for a miniature two-dimensional chromatograph and a working method thereof. The device is technically characterized by comprising a power supply subassembly, a miniature water removal cold trap and an enrichment thermal analyzer sampling system, wherein the enrichment thermal analyzer sampling system comprises chromatographic columns on two side surfaces of a bearing box; one side of each of the chromatographic columns is provided with a quartz adsorption tube; one side of the quartz adsorption tube is provided with a spiral first heating resistance wire; the device further comprises a main cooling plate located at an exterior of the first heating resistance wire; the device further comprises a two-dimensional chromatographic column temperaturecontrol box; the two-dimensional chromatographic column temperature control box comprises a heat dissipation base; the chromatographic columns are disposed on the heat dissipation base; second heating resistance wires are wrapped on outer walls of the chromatographic columns; heat insulation sleeves are connected to an upper part of the heat dissipation base in an insertion manner; and the devicefurther comprises a stop-flow modulator and a miniature photoionization detector. According to the pretreatment device for the miniature two-dimensional chromatograph and the working method thereof disclosed by the invention, through water-removal treatment and refrigeration enrichment adsorption treatment, an adsorption component is rapidly heated and released, a detected component is separatedby the two-dimensional chromatographic columns under different temperature gradients and is detected by the miniature photoionization detector to form a two-dimensional chromatogram.

Description

technical field [0001] The invention relates to the technical field of instrument and equipment manufacturing, in particular to a pretreatment device of a miniature two-dimensional chromatograph and a working method thereof. Background technique [0002] Gas chromatography has the characteristics of high efficiency, rapidity and wide application. It has developed into a key technology to solve various separation and analysis problems in the study of organic substances. It is widely used in pharmacy, life science, medicine, food science, petrochemical industry and environmental protection. fields are widely used. A usual chromatograph is composed of a high-pressure carrier gas system, a sampler, a chromatographic column, a detector, a recorder, etc. During the application process, a chromatographic column is often used for separation, that is, one-dimensional chromatographic separation. For complex systems, such as natural products, body fluids, etc., usually a sample contai...

AI Technical Summary

Problems solved by technology

For two-dimensional separation and detection of VOCs, it is necessary to use liquid nitrogen to separate the chromatographic column, and the instrument containing liquid nitrogen is bulky and heavy. The detector of the two-dimensional chromatography instrument is generally a mass spectrometer (MS) or a flame ionization detector ( FID) are large in size, and the enrichment thermal desorber is also large in size, which is not conducive to handling or carrying. The price of the instrument is also relatively expensive, bulky and heavy, and the energy consumption of the instrument is high. Therefore, the detection of atmospheric VOCs is limited to the laboratory. It is necessary to manually go to the site to sample the samples and bring them back before testing

This greatly hinders the timeliness and convenience of detection, so it is very important to develop a miniature two-dimensional chromatograph that is small in size, low in cost, and easy to carry.

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