Preparation method of artificial bear bile dripping pills

Abstract

The invention relates to the technical field of medicines, in particular to a preparation method of artificial bear bile dripping pills. The preparation method comprises the following steps of S1, performing crushing, weighing and blending on raw materials: crushing artificial bear bile powder with a universal crushing machine, performing screening, and performing sealing for standby application;S2, performing compounding and heat preservation: heating oil bath to the temperature of 60-95 DEG C, adding polyethylene glycol 6000 to a blending jar in several times, wherein the addition quantityeach time is 2-20kg, performing heating and stirring for melting, after the polyethylene glycol completely melts, performing stirring, adding the crushed artificial bear bile powder, performing mixingto obtain cream which is dark pale brown to dark brown, and putting the compounded materials to be dripped in the blending jar for heat preservation; and S3, preparing dripping pills: adding 50-300kgof light weight liquid paraffin to a pill dripping machine as a condensing agent, wherein the temperature of oil bath in the pill dripping machine rises to 60-95 DEG C, adding materials to be drippedinto a seasoning jar, and performing dripping with 2.5# dripping heads of 1 row of dripping trays. According to the preparation method disclosed by the invention, the artificial bear bile powder is used as a raw material medicine, an artificial bear bile dripping pill preparation is developed, and the problem that natural bear bile raw materials are valuable and scarce is solved.

Description

technical field [0001] The invention relates to the technical field of medicines, in particular to a preparation method of artificial Xiongdan dripping pills. Background technique [0002] Bear bile, obtained from the dried gallbladder bile of black bears or brown bears, has the effects of clearing away heat, calming the liver, and improving eyesight. Its main component is tauroursodeoxycholic acid (TUDCA). Bear bile is one of the four famous and precious animal medicines. It has a history of more than 2,000 years of use, and a large number of prescriptions contain bear bile. my country's annual output of bear bile powder is about 30 tons, which still cannot meet the needs of human health. At present, the contradiction between supply and demand of high-end bear bile powder is increasingly prominent and the market demand for bear bile powder for low-end raw materials continues to increase, which makes the price of bear bile powder rise steadily, and the market price has exce...

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And strictly limit the application for new drug registration containing the above endangered medicinal materials

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