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Pharmaceutical application of beta 2 receptor agonist

A β2 receptor and agonist technology, which is applied in the direction of medical preparations containing active ingredients, pharmaceutical formulas, drug combinations, etc., can solve problems such as the decline in drug efficacy, and achieve obvious effects, small side effects, and small doses of drugs.

Inactive Publication Date: 2019-06-14
陕西卓力时代人力资源有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Long-term use of short-acting β2-receptor agonists (including inhalation and oral administration) can lead to a decrease in the efficacy of the drug, which can only be restored after a period of withdrawal

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0010] β2 receptor agonists can be used to prevent the onset of allergic seasonal cough. The application method is: one month before the arrival of the allergy season, start inhaling β2 receptor agonists twice a day. Patients with Spring Festival allergies can inhale two In January, patients with autumn allergies can stop inhaling after inhaling Bailu, so as to prevent allergic seasonal cough.

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PUM

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Abstract

The invention relates to a pharmaceutical application of a beta 2 receptor agonist and an application in preparation of a drug for preventing seasonal cough attacks. The drug is taken through oral inhalation to achieve the purpose of local drug administration. Compared with the systemic drug administration, the dosage is small, the side effects are small and the effect is obvious. After fifty patients with seasonal cough caused by allergic constitution inhale the drug twice per day one month before the allergy season and take for two months, forty five patients do not suffer seasonal cough attack in the allergy season and five patients have mild symptom of expectoration but do not have obvious symptoms of seasonal cough attacks. Therefore, the obvious effective rate is up to 90% and the effective rate is up to 100%.

Description

technical field [0001] The present invention relates to the medical application of a β2 receptor agonist. Background technique [0002] Seasonal cough caused by allergies is usually seasonal, usually in spring and late summer and early autumn. Patients are often allergic to a certain plant powder in these two seasons, leading to allergic asthma or seasonal cough , Symptoms last about a month. [0003] Commonly used short-acting β2-agonists are salbutamol and terbutaline. Inhalation administration, including aerosol, dry powder and nebulized solution, can directly act on bronchial smooth muscle. Its anti-asthma effect is fast, usually takes effect within a few minutes, and the curative effect can last for 4-6 hours. It is the first choice drug for relieving acute symptoms of asthma, and can also be used as a preventive drug for exercise-induced asthma. Drug overdose or adverse reactions include palpitations, skeletal muscle tremor, cardiac arrhythmia and hypokalemia, etc.,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K45/00A61K9/12A61P11/14A61P37/08A61K31/137
Inventor 程淑清牛清玲
Owner 陕西卓力时代人力资源有限公司