14results about How to "Avoid high concentrations" patented technology

The invention belongs to the technical field of edible mushroom culture, and particularly relates to an edible mushroom culture device which comprises a culture tank, an air inlet barrel and an air draft barrel are fixedly communicated with the tank wall of the culture tank in an oblique symmetry mode, dustproof nets are fixedly installed at the ends of the air inlet barrel and the air draft barrel, an exhaust fan is fixedly installed in the air draft barrel, and the exhaust fan is fixedly installed in the air draft barrel. A temperature sensor, a humidity sensor and a carbon dioxide concentration sensor are respectively arranged on the tank wall of the culture tank. According to the invention, the temperature, humidity and carbon dioxide concentration in the culture process can be monitored in real time, the culture temperature, humidity and carbon dioxide concentration can be regulated and controlled in real time based on monitored values, and the growth process of edible mushrooms can be reversely and rapidly inferred based on the change speed of the carbon dioxide concentration. And on the basis of the growth process of the edible mushrooms, set threshold values of the culture temperature and humidity are automatically regulated and controlled, and the culture temperature and humidity are accurately regulated and controlled by automatically following the growth process of the edible mushrooms, so that the culture quality is improved.

The application provides a kind of mitochondrial function optimization additive for cell culture, preparation method and application, belong to cell culture technical field.The additive includes core active ingredient, auxiliary component and carrier, and the core active ingredient includes D-Arg-Cha-Lys-Phe-NH2 Polypeptide, ubiquinone-10 phosphate, reduced glutathione and alpha-lipoic acid.The application forms a multi-target core active system through the synergy of the four, realizes the triple synergistic protection of stabilizing mitochondrial cardiolipin, maintaining mitochondrial morphology and membrane potential, and reducing mitochondrial ROS, which can significantly improve cell culture quality.When applied, the mitochondrial cardiolipin content can be increased by more than 50%, the mitochondrial abnormality ratio can be reduced to less than 12%, the membrane potential positive cell ratio can be increased to more than 86%, the mitochondrial ROS level can be reduced by more than 40%, and the cell proliferation rate can be increased by more than 25%, which is suitable for in vitro culture of various eukaryotic cells, and the preparation process is simple and has no cytotoxicity.

The present disclosure relates to the development of a new tumor engager therapeutic drug and the use thereof. The therapeutic drug contains a bispecific antibody that binds to GPC3 and CD3, wherein the bispecific antibody contains a first binding domain that binds to GPC3 on the surface of a target cell and a second binding domain that binds to CD3 on the surface of a T cell. The bispecific antibody can inhibit tumor growth at a very low dose and effectively inhibit the growth of a transplanted tumor in an immune reconstitution mouse. A toxicological study conducted in cynomolgus monkeys also shows that animals have good tolerance to the bispecific antibody, and the efficacy and safety of the bispecific antibody are superior to those of similar antibodies.

The invention discloses a sulfur hexafluoride and mixed gas on-site rapid gas supplementing device and method, and relates to the technical field of gas mixing and supplementing of GIL / GIS equipment, the sulfur hexafluoride and mixed gas on-site rapid gas supplementing device comprises a sulfur hexafluoride inflation unit, a nitrogen inflation unit, a gas supplementing main pipeline unit, a vacuumizing unit and a gas chamber gas return unit; the sulfur hexafluoride inflating unit and the nitrogen inflating unit are communicated with the gas supplementing main pipeline unit; and the vacuumizing unit is communicated with the air chamber air return unit and the air supply main pipeline unit. The device has the beneficial effects that the special sulfur hexafluoride inflating unit and the nitrogen inflating unit are arranged, and the two-position three-way valve is combined to control the proportion of two gases entering the gas supplementing main pipeline, so that the originally designed mixing proportion of sulfur hexafluoride and nitrogen can be maintained or recovered when the mixed gas is supplemented; and the problem that the concentration of sulfur hexafluoride is too high due to pure use of pure sulfur hexafluoride for gas supplementation is avoided.

The application discloses a wastewater treatment device and a working method thereof. The device comprises a water storage pool, a movable base movably connected to the water storage pool, a moving unit and a particle throwing unit arranged on the movable base, a solution throwing unit arranged on the particle throwing unit, and a measuring unit connected to the solution throwing unit. The device can avoid the concentration of a certain area being too high to reduce the dissolution speed of the medicament, and the blades on the crushing rollers of the collecting assembly can also have a mixing effect, thereby accelerating the dissolution speed of the medicament.

This invention discloses a rapid deep peak-shaving system and method for co-firing biomass in a coal-fired circulating fluidized bed, belonging to the field of fuel combustion technology. This invention controls in-furnace combustion by adjusting the biomass co-firing ratio and feeding position, thereby improving the response rate under varying loads. It utilizes a bed material storage and conveying system to recycle the bed material in the furnace, recover the sensible heat of high-temperature ash slag, and control the material concentration and circulation loop stability during load changes. Furthermore, this invention introduces heated, clean, low-oxygen flue gas into the furnace, suppressing the formation of excessive nitrogen oxides and facilitating bed temperature stability during rapid load changes.

The invention provides a thermal barrier coating exhaust passage with an anti-tempering function and an installation method, and relates to the technical field of thermal barrier coatings and diesel engine exhaust passages, the thermal barrier coating exhaust passage comprises an exhaust passage body, the exhaust passage body is coated with a thermal barrier coating, and the thermal barrier coating comprises a first bonding layer, a ceramic layer and a second bonding layer from outside to inside; the first bonding layer and the second bonding layer are made of the same material, an exhaust passage heat exchanger is installed on the exhaust passage body, and a spiral static mixer is installed on the inner side of the exhaust passage body, the exhaust passage with a spiral mixing structure is designed, mixing of incomplete combustion tail gas can be effectively promoted, in addition, a heat exchange channel is arranged on the outer side of the exhaust passage, and the heat exchange efficiency is improved. According to the design, heat transferred to the exhaust passage from the high-temperature cylinder cover can be reduced, heat on the high-temperature wall surface of the exhaust passage can be taken away, and the heat exchange passage and the exhaust passage are combined, so that the temperature of the wall surface of the exhaust passage is effectively reduced, and meanwhile, the situation that the local gas concentration is too high is avoided.

The utility model discloses a sialwood savoury alcohol esterification reaction device which comprises a reaction kettle, a stirring device arranged in the reaction kettle, a heating plate arranged in the reaction kettle, a feeding channel arranged at the top of the reaction kettle, a telescopic channel rotatably mounted at the upper end in the reaction kettle, and a driving component arranged at the top of the reaction kettle, the top of the reaction kettle is provided with a telescopic channel, the top of the reaction kettle is provided with a height adjusting assembly for driving the telescopic channel, the bottom of the telescopic channel is provided with a plurality of uniformly distributed discharge ports, and the bottom of the telescopic channel is provided with a material dispersing plate extending into the liquid level. Raw materials enter the telescopic channel from the feeding channel and then are discharged from the discharging port, the telescopic channel is driven by the driving assembly to rotate, so that the raw materials entering the reaction kettle are rapidly diffused through the material dispersing plate, the problem that the concentration of local raw materials is too high when the raw materials are added is effectively avoided, and the diffusion speed of the raw materials is increased; the reaction effect of the esterification reaction is ensured.

The utility model discloses a kind of thermochemical energy storage reactors, including cylinder, heating device, heat exchange coil subassembly and water vapor distributor, cylinder side is equipped with heat exchange medium inlet pipe, cylinder other side is equipped with heat exchange medium outlet pipe, cylinder inside two sides are equipped with tube sheet, energy storage medium is filled in the shell side between the tube sheet of both sides of cylinder;Heating device is fixed in cylinder inside by several fixed frame;Heat exchange coil subassembly includes helical heat exchange pipe;Water vapor distributor includes concentric ring pipe group being set to both sides of cylinder, the ring pipe of both sides corresponding position is communicated by several steam pipes, and both ends of water vapor distributor each is equipped with two water vapor inlet and outlet.The utility model distributes the multiple steam pipes in water vapor distributor evenly in energy storage medium, enhances the flowability of water vapor in cylinder, strengthens the fluidization of solid particles in cylinder, reduces the degree of solid particle agglomeration, enhances the stability of system operation.

The invention provides a batching system for multi-component silicone oil and a use method of the batching system. The batching system comprises a raw material supply unit; the automatic weighing unit comprises a metering pump communicated with each raw material supply unit and a metering tank connected with an outlet of the metering pump; the mixing unit comprises a mixing tank located below the metering tank, a stirrer arranged in the mixing tank and a temperature control module used for controlling the temperature in the mixing tank; the material storage unit comprises a middle storage tank and a first pumping mechanism for pumping the materials in the mixing tank to the middle storage tank; the feeding unit comprises a second pumping mechanism used for pumping the materials in the middle storage tank to a downstream coating device; and the central control unit is used for coordinating and controlling the automatic operation of the whole system. The batching system for the multi-component silicone oil can accurately feed materials, and the viscosity of the silicone oil and the stability of the subsequent coating weight are effectively guaranteed; manual operation is not needed in the batching process, full-automatic operation is achieved, and harm to human bodies is reduced.

The invention belongs to the technical field of tunnel construction, and particularly relates to a dust falling device for tunnel construction, which comprises a water tank, a water guide pipe is rotatably mounted on the inner wall of the water tank, a dust falling assembly is arranged on the outer side of the water guide pipe, and a mounting assembly for mounting the dust falling assembly is arranged above the water tank. An angle adjusting assembly used for adjusting the angle of the mounting assembly is arranged on the inner side of the mounting assembly, and a driving assembly is arranged on the inner side of the water tank. Through rotation of the dust falling assembly, the 360-degree spraying effect can be achieved, and no-dead-corner spraying is conducted on the surrounding environment, so that the dust falling coverage range is effectively widened, the dust catching efficiency is improved, and the problem that the dust concentration of a local area is too high due to angle limitation of traditional fixed dust falling equipment is solved; the angle adjusting assembly can adjust the angle of the dust falling assembly in a reciprocating mode, a three-dimensional dust falling space is formed by adjusting the angle of the dust falling assembly, and the dust falling effect of the device is improved.

The present disclosure relates to the development and application of a T-cell engager therapeutic agent. A T-cell engager is a T-cell bispecific antibody, and the bispecific antibody contains a first binding domain bound to BCMA on the surface of a target cell and a second binding domain bound to CD3 on the surface of a T cell. The bispecific antibody has good tolerance, can effectively block the binding of the BCMA to a receptor APRIL, and has no adverse reaction, such as weight loss.

The present invention relates to: a target nucleic acid amplification method capable of amplifying a very low concentration of a target nucleic acid with high specificity; and a composition for amplifying a target nucleic acid by using same and, more specifically, to: a method for producing an amplicon of a target nucleic acid with high specificity by using, when a target nucleic acid is present, a guide probe binding to the target nucleic acid, a partial primer capable of amplifying the target nucleic acid by binding to the guide probe, and a clamping probe that inhibits the amplification of nucleic acids other than the target nucleic acid; and a composition for a polymerase chain reaction (PCR) therefor. The target nucleic acid amplification method according to the present invention is advantageous in that a target nucleic acid present at a very low concentration can be amplified using a guide probe which binds to all hybridizable nucleic acids present in a sample and helps a partial primer bind to a target nucleic acid detection site, nucleic acids other than the target nucleic acid differ in amplification rate due to the sequence specificity of the partial primer, and the target nucleic acid can be detected with high specificity since the amplification of nucleic acids other than the target nucleic acid is suppressed by a clamping probe, and thus is effective in molecular diagnosis, prenatal diagnosis, early diagnosis, cancer diagnosis, heredity-related diagnosis, genetic trait diagnosis, diagnosis of infectious bacteria, identification of drug-resistant bacteria, forensic medicine, classification of the species of organisms, and the like.

The utility model relates to the field of blending integration devices, and discloses a cleaning fluid blending integration device which comprises a supporting table, a stirring barrel is arranged on the upper surface of the supporting table, a material injector is fixedly connected to the upper portion of the inner wall of the supporting table, and a liquid distributing assembly is arranged on the lower surface of the material injector. A motor frame is fixedly connected to the outer wall of the supporting table, a motor is arranged on the left side of the motor frame, a fixing rod is fixedly connected to the position, close to the center, of the inner wall of the stirring barrel, a first gear is fixedly connected to the outer wall of the fixing rod, and a rotating disc is rotationally connected to the inner wall of the stirring barrel. According to the stirring device, through the feeding assembly, the second gear and the first gear, when an operator operates the stirring device, the first gear drives the second gear to rotate when rotating, and the rotating disc rotates during synchronization, so that the rotating stirring rods on the two sides can rotate around the fixed rod while the fixed rod is used for stirring, and the practicability of the stirring device is enhanced.