A kind of preparation method of mixed concentrated platelet

A platelet and platelet-rich technology, applied in the field of medical blood transfusion, can solve the problems of inconvenient promotion, aggravating the circulatory pressure of transfusion recipients, and low volume of mixed platelet concentrates, and achieves the effects of satisfying usage requirements, low volume and saving blood resources.

Active Publication Date: 2021-07-02
西安市中心血站(陕西省血液中心)
View PDF6 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The present invention provides a preparation method of mixed concentrated platelets, which is used to solve the problem in the prior art that the capacity of mixed concentrated platelets is much larger than the treatment volume of apheresis platelets, which is not easy to popularize and will also increase the circulation pressure of transfusion patients problem, achieved the technical effect of low volume of mixed concentrated platelets, and the platelet count can meet the requirements of use, saving blood resources

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A kind of preparation method of mixed concentrated platelet

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0022] figure 1 It is a preparation method of mixed concentrated platelets in the embodiment of the present invention, such as figure 1 As shown, the method includes:

[0023] Step 1: Obtain the collected whole blood of the first preset volume.

[0024] Specifically, the collected whole blood is the blood of the blood donors at the voluntary blood donation sites, and the blood donors who can collect blood are all in good health, that is to say, the physical condition of the collectors must meet the health indicators, that is, meet the GB18467-2011 "Health Examination Standards for Blood Donors". For example, whole blood with a capacity of 390-410ml can be collected through a five-unit blood collection bag, stored and transported at room temperature, and sent to the component department for further processing within 6 hours after blood collection.

[0025] Step 2: According to the first preset condition, the whole blood is centrifuged with a centrifuge, wherein the whole blo...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a method for preparing mixed and concentrated platelets, which belongs to the technical field of medical blood transfusion, by obtaining whole blood collected in a first preset volume; according to the first preset condition, using a centrifuge to centrifuge the whole blood Using a blood component separator to separate the plasma layer in the centrifuged whole blood according to the platelet-poor plasma layer and the platelet-rich plasma layer; using the blood component separator to separate the white blood in the centrifuged whole blood Separating the membrane layer; using the blood component separator to transfer the platelet-rich plasma to a buffy coat bag, and obtaining a platelet-rich buffy coat; storing the platelet-rich buffy coat at a preset temperature; Repeat the above steps to obtain multiple copies of the platelet-rich buffy coat of the same blood type; under the second preset condition, after centrifugation, concentrated platelets are obtained, and pooled into the platelet storage blood bag of the same blood type to obtain mixed concentrated platelets. It has achieved the technical effects of low volume of mixed concentrated platelets, platelet counts can meet the use requirements, and save blood resources.

Description

technical field [0001] The invention relates to the technical field of medical blood transfusion, in particular to a preparation method of mixed concentrated platelets. Background technique [0002] The professional term for platelets separated from whole blood is called concentrated platelets. Generally, 200ml whole blood can separate 1U concentrated platelets, and the PLT is 2×10 10 / bag, and the treatment volume of a patient's infusion is about 10-12U. The traditional process not only has cumbersome preparation process, low platelet recovery rate, but also inconvenient clinical transfusion. There are two conventional methods for preparing mixed platelet concentrates. One is to collect 5-7 bags of concentrated platelets into special platelet storage bags by aseptic connection to make mixed platelet concentrates. This method is consistent with the terms and definitions in GB18469-2012 "Quality Requirements for Whole Blood and Blood Components"; the other method is to poo...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Patents(China)
IPC IPC(8): A61M1/02A61K35/19
Inventor 张雅莉
Owner 西安市中心血站(陕西省血液中心)
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap