A kind of antidiarrheal Muzi formula granules, preparation method and detection method

Abstract

The invention relates to antidiarrheal muzi formula granules, a preparation method and a detection method. The formula granules are composed of antidiarrheal muzi dry paste powder, polyvinylpyrrolidone and talcum powder. The present invention is obtained by extracting, concentrating, drying and granulating the antidiarrheal single herb, which is convenient for doctors to carry out syndrome differentiation and treatment, and can be added or subtracted according to the syndrome; its detection method is to use thin layer chromatography to identify antidiarrheal and cone serine, and use Liquid chromatography was used to detect the content of conesinine in formula granules. Under different TLC, temperature and humidity conditions, the chromatographic spots of this method are clear, the separation meets the requirements, the Rf value is moderate, and good identification chromatograms can be obtained under different conditions. The verification test shows that this method has good reproducibility and durability Good performance, using liquid chromatography to detect the content of cone silk alkali, the result is accurate and reliable, the method is simple and repeatable, and can effectively control the quality of the anti-diarrheal Muzi formula granules.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a preparation method and a quality detection method of antidiarrheal Muzi formula granules. Background technique [0002] Muzi Zhixie, Tibetan medicine name: Dumoniu. It is the dry seed of Holarrhena antidysentericaWall.ex A.DC. Zhixie Muzi is an arbor, up to 10m high, about 20cm in diameter at breast height, with latex; bark light gray, branches with lenticels and pubescence. Opposite leaves, broadly ovate or nearly round, 10-20cm long, 4-11.5cm wide, pubescent on both sides, pubescent on old leaves, corymb-shaped cymes, sepals 5-lobed, inner base with a 5 glands; corolla white, saucer-shaped, pubescent inside and outside the corolla tube, base enlarged, upper part 5-lobed, stamens 5, inserted near the base of the corolla tube, ovary composed of 2 free carpels , follicles are twin, inwardly curved, 20-43cm long, 5-8mm in diameter, with white spots, and the top of the seeds is crowned ...

AI Technical Summary

Problems solved by technology

[0003] The traditional decocting method of antidiarrheal Muzi decoction pieces is extremely troublesome. Patients do not know much about the amount of water added, soaking time, heat, decoction time, first decoction, and second decoction of antidiarrheal Muzi decoction pieces.

The traditional method of decocting traditional Chinese medicine with water can not control the content of antidiarrheal tree, which leads to the safety of the medicine can not be guaranteed, but has side effects on the human body

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