Gentiana urnula formula granule, preparation method and detection method thereof

Abstract

The invention relates to a gentiana urnula formula granule, a preparation method and a detection method. The formula granule is composed of dry gentiana urnula paste powder, dextrin and polyethylene glycol. The gentiana urnula formula granule is prepared from a single medicine of gentiana urnula through extracting, concentrating, drying and pelletizing; treatment based on syndrome differentiationby a physician can be facilitated, the dosage is increased or decreased based on the syndrome; the detecting content is to identify gentiana urnula glycoside a through the thin layer chromatography, and detect the content of the gentiana urnula glycoside a in the formula granule through the liquid chromatography. By adopting the method, under different thin layer plates, temperature and humidity conditions, the spots on chromatograms are clear, the separation is in accord with the requirements, the Rf value is moderate, and better identification chromatography can be obtained under different conditions; a verification test shows that the method provided by the invention is good in reproducibility and durability, the liquid chromatography is adopted to detect the content of the gentiana urnula glycoside a, the result is accurate and reliable; the method is simple, good in repeatability, and can be used for effectively controlling the quality of the gentiana urnula formula granule.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a preparation method and a quality detection method of Wunu Gentian formula granules. Background technique [0002] Wunu Gentian (scientific name: Gentiana urnula H.Smith): a perennial herb of Gentianaceae, 4-6 cm high, with well-developed stolons. Fibrous roots are numerous, slightly fleshy, pale yellow. Branches numerous, sparsely clustered, erect, very low, with shortened internodes. The leaves are densely arranged in imbricate tiles, the base is black-brown residual leaves, the middle is yellow-brown dead leaves, the upper part is green or lavender fresh leaves, fan-shaped and truncated, flowers are solitary, and 2-3 clusters are rarely clustered on the top of branches. Base surrounded by upper leaves; no pedicel; calyx tube membranous, lobes green or purple, leaf-shaped, same shape as leaves, capsule exposed, ovate-lanceolate, 1.5-1.8 cm long, apex acute, base obtuse , slender sta...

AI Technical Summary

Problems solved by technology

[0004] The traditional decoction method of Wunu gentian decoction pieces is extremely troublesome. Patients do not know much about the amount of water added, soaking time, heat, decoction time, decoction first and then decoction, etc., resulting in not decocting according to the requirements

The traditional method of decocting traditional Chinese medicine with water cannot effectively control the efficacy of the medicine, which leads to the inability to guarantee the safety of the medicine

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