NRAS gene mutation detection kit

Abstract

The invention discloses an NRAS gene mutation detection kit. The NRAS gene mutation detection kit comprises a rack; a storage cavity penetrating in a front and back manner is formed in the rack; a rotating frame is arranged in the storage cavity; a rotating cavity is formed at the lower end of the storage cavity; a rotating device connected with the rotating frame is arranged in the rotating cavity; a movable device is arranged at the lower end of the rack; a putting cavity is formed in the rotating frame; a putting mechanism is arranged in the putting cavity; a partition plate extending up and down is arranged at the middle part of the putting cavity; an up-and-down sliding mechanism and a front-and-back sliding mechanism are arranged in the partition plate and the inner wall of the putting cavity; a transmission cavity is formed at the lower end of the putting cavity; a motor is arranged on the lower end surface of the transmission cavity in an embedded manner; and the tail end of anoutput shaft of the motor is fixedly connected with a driving straight gear. The NRAS gene mutation detection kit is simple in structure and high in functionality, and has the high practicability.

Description

technical field [0001] The invention relates to the technical field of kits, in particular to an NRAS gene mutation detection kit. Background technique [0002] The NRAS gene is a member of the RAS oncogene family, located on chromosome 1, with a total length of 85kb. The mammalian RAS gene family includes c-Hras1, c-K-ras2 and N-ras genes. The ras gene family encodes a protein with 188-189 amino acid residues and a molecular weight of 21KD, that is, the P21 protein. Its amino acid sequence is highly conserved, with only 40 amino acid differences at the C-terminal. RAS proteins have GTP / GDP binding ability and GTPase activity, and their normal function is G protein-like regulatory proteins, which have signal transduction from membrane-bound receptors to adenylate cyclization process, and participate in the normal regulation of cell cycle . RAS gene activation is mainly through (1) point mutations in the coding region; (2) insertion activation; mutation activation of the RA...

AI Technical Summary

Problems solved by technology

At present, NRAS gene mutation detection reagents need to be transported and stored in special kits during use. If there is no effective placement device, the reagents will be placed randomly. The existing NRAS gene mutation detection reagent storage kits are simple in structure and functional. Single, cannot meet the needs of mass storage, and is not easy to take quickly

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