Infection fighting drug eluting device

A drug and antimicrobial technology, applied in drug delivery, pharmaceutical formulation, medical science, etc.

Active Publication Date: 2019-08-02
CARDIAC PACEMAKERS INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The cost of such an infection, not only in nature but also in terms of the physical and emotional stress suffered by the patient, can be significant

Method used

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  • Infection fighting drug eluting device
  • Infection fighting drug eluting device
  • Infection fighting drug eluting device

Examples

Experimental program
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Embodiment Construction

[0053] A more complete understanding of the invention can be obtained by reference to the following detailed description of various aspects and embodiments of the invention. The following detailed description of the invention is intended to illustrate the invention rather than limit the invention.

[0054] According to various aspects of the present disclosure, it should be understood that the various embodiments may be implemented in any suitable medical device implanted in a patient including electrical leads electrically connected to a housing, such as the cardiac rhythm management (CRM) system described below. For example, an embodiment may be used with a subcutaneously implanted implantable cardioverter defibrillator (ICD) housing and lead system. Other such implanted medical devices include, but are not limited to, implanted heart monitors and neurostimulation systems, such as spinal cord stimulation or deep brain stimulation devices.

[0055] figure 1 is a schematic i...

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PUM

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Abstract

An implantable drug eluting medical device includes a polymer substrate having a surface, a first plurality of nanofibers, and at least one antimicrobial drug. Each of the first plurality of nanofibers includes a first portion interpenetrated with the surface of the substrate to mechanically fix the nanofiber to the substrate, and a second portion projecting from the surface. The at least one antimicrobial drug is disposed within or among the second portion of the first plurality of nanofibers.

Description

[0001] Cross References to Related Applications [0002] This application claims priority to Provisional Application No. 62 / 435,829, filed December 18, 2016, which is hereby incorporated by reference in its entirety. technical field [0003] The present invention relates to the prevention of infections associated with implantable medical devices. More specifically, the present invention relates to anti-infective drug outflow devices for implantable medical electrical leads. Background technique [0004] Medical devices can be implanted in subcutaneous pockets to support sensing intrinsic physiological electrical activity, delivering therapeutic stimuli to patient tissue, or delivering other treatments to specific treatment sites. For example, a pulse generator may be implanted in a subcutaneous pocket on the patient's chest, with one or more electrical leads extending from the pulse generator to a treatment site within the patient's body. [0005] Implanting a medical devi...

Claims

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Application Information

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IPC IPC(8): A61L31/04A61L31/10A61L31/14A61L31/16
CPCA61L31/10A61L31/146A61L2400/12A61L31/04A61L31/16A61L2300/404A61L31/148A61N1/0568D01D5/003D10B2331/06D10B2509/00
Inventor 玛丽·M·拜伦大卫·R·伍尔夫曼安吉洛·夫茨亚当·麦格劳丹尼尔·弗兰克森格雷戈里·J·舍伍德约瑟夫·T·德莱尼阿德尼伊·O·阿雷姆
Owner CARDIAC PACEMAKERS INC
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