Application of Hemin@Zn-MOF material in catalytic oxidation

Abstract

The invention discloses an application of a Hemin@Zn-MOF material in catalytic oxidation. The application comprises the following steps: S1, synthesizing Zn-MOF: S11, separately weighing Zn(NO3)2.6H2O(0.15g, 0.50 mmol), a ligand H3TATB (0.045g, 0.10 mmol) and an auxiliary ligand bpe (0.018 g, 0.10 mmol), placing the weighed reagents into a glass vial of 20 mL, adding 5 mL of dimethyl formamide (DMF) and 1 mL of H2O, and carrying out mixing and stirring; and S12, dropwise adding 0.7mL of a HNO3 solution (6 mol / L), carrying out stirring for 30 minutes, and then carrying out a reaction for 2 days in a drying oven at a temperature of 120 DEG C. The invention relates to the technical field of heme. According to the application of the Hemin@Zn-MOF material in catalytic oxidation, the hydrogen bond acting force between exposed free carboxyl of the two-dimensional Zn-MOF and carboxyl of the heme is utilized, the pi-pi acting force of the Zn-MOF ligand and a heme porphyrin ring is combined, and the combination between the Zn-MOF ligand and the heme is enhanced by the double acting force, so that chlorhematin is powerfully fixed on the material. In addition, the free carboxyl uniformly distributed in the Zn-MOF structure can easily achieve load uniformity of the heme. The Zn-MOF shows good stability in various solvents and pH (=1-10) environments, and catalytic application of the composite material is facilitated.

Description

technical field [0001] The invention relates to the technical field of hemin, specifically the application of Hemin@Zn-MOF materials in catalytic oxidation. Background technique [0002] Heme has important applications in electron transport and redox, and blood proteins are an important subclass of metalloproteins, which use iron protooxymorpholine (feppix) as a cofactor and are responsible for various basic metabolic functions, including gas Binding, electron transport, and oxidoreductases, regioselectivity make them extreme electron catalysts, and the E-ciency of these systems is due in part to the versatility of feppix, so there is interest in exploiting this outside of its protein environment. The catalytic ability of this prosthesis is of great interest. [0003] At present, the loading of heme on gel, zeolite, polymer film, carbon nanotube, nanosheet and other materials has been realized, but because the above materials are different from the original protein host, th...

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Problems solved by technology

[0004] Aiming at the deficiencies of the prior art, the present invention provides an application of Hemin@Zn-MOF material in catalytic oxidation, which solves the problem that the existing heme lacks good active loading sites, which causes the heme to fall off easily during use. question

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