Preparation method of organic phosphor-supported hollow mesoporous SiO2 hydrophilic phosphorescent nanoprobe

A nanoprobe and organophosphorus technology, which is applied in the field of preparation of hollow mesoporous SiO2 hydrophilic phosphorescent nanoprobes loaded with organic phosphors, can solve the problems of insufficient removal of PS template spheres and cumbersome removal of PS template spheres
CN110205113AInactive Publication Date: 2019-09-06HARBIN INST OF TECH SHENZHEN GRADUATE SCHOOL
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
HARBIN INST OF TECH SHENZHEN GRADUATE SCHOOL
Publication Date
2019-09-06
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention belongs to the technical field of preparation of materials, and concretely relates to a preparation method of an organic phosphor-supported hollow mesoporous SiO2 hydrophilic phosphorescent nanoprobe. The hydrophilic phosphorescent nanoprobe (Phosphors@HMSNPs) prepared by the preparation method combines the respective advantages of an organic phosphorescent crystal with hollow mesoporous silica nanoparticles (HMSNPs), can efficiently emit phosphorescence and can be stably dispersed in the water environment, so the nanoprobe can be used for phosphorescent bioimaging.
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Description

technical field

[0001] The invention belongs to the technical field of material preparation, in particular to a hollow mesoporous SiO loaded with an organic phosphor 2 Preparation method of hydrophilic phosphorescent nanoprobe. Background technique

[0002] Ultra-long organic phosphorescence can eliminate the interference caused by transient background fluorescence and significantly increase the signal-to-noise ratio, so it is very suitable for biological imaging.

[0003] Under the action of molecular motion and quenching factors such as oxygen and water molecules in the environment, non-metallic organic phosphors undergo fast non-radiative transitions, which limit their phosphorescence performance. Today, crystallization is considered as one of the effective ways to suppress nonradiative transitions, which can provide rigid confinement for phosphorescent molecules. However, most organic crystals are oil-soluble and cannot be well dispersed in aqueous environments, which ...

Claims

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