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Using film to provide a preform for micro injection molding process

A thin film and component technology, applied in the field of microneedle array

Inactive Publication Date: 2019-10-25
SABIC GLOBAL TECH BV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

While there are many benefits to using microneedles and considerations regarding their formation, there are still some challenges in microneedle production

Method used

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  • Using film to provide a preform for micro injection molding process
  • Using film to provide a preform for micro injection molding process
  • Using film to provide a preform for micro injection molding process

Examples

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Embodiment Construction

[0011] The present disclosure can be understood more readily by reference to the following detailed description of the disclosure. Microneedles can be used to deliver therapeutic agents or withdraw interstitial fluid or blood without penetrating tissue as deeply as conventional needles. Such microneedles can be used individually or as an array of needles. Needles are generally produced by mass production at relatively low cost. To effectively function as a therapeutic agent delivery mechanism or therapeutic tool, the microneedles must be sharp enough to penetrate the dermal surface while still maintaining the benefit of being relatively painless. Injection molding is a means of mass-producing microneedle arrays at low cost and with high precision regarding the shape of the needles. Nonetheless, while injection molding production has its advantages, the replication of microneedle arrays can be disrupted due to filling variations of the microneedle mold or microstructure. Inj...

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Abstract

A mold assembly 100 for forming a microneedle array, wherein the mold assembly facilitates expulsion of trapped gasses from the molding system. The mold assembly may comprise a first mold portion 102comprising a plurality of recesses 104 formed therein, a second mold portion 106 disposed adjacent the first mold portion, wherein a surface of the second mold portion and the plurality of recesses ofthe first mold portion define a mold cavity, a mold film insert 112 disposed within the mold cavity between the first mold portion and the second mold portion of the mold assembly, the mold film insert comprising a plurality of perforated layers 114, each of the perforated layers comprising a plurality of perforations.

Description

technical field [0001] The present application relates to the formation of microneedle arrays using mold assemblies for precise replication. Background technique [0002] Microscopy is attractive for the delivery of certain therapeutic agents. These needles may be particularly desirable as a mode of therapeutic delivery, since it is possible to replace syringe-type injections with needles with painless alternatives. Unlike traditional syringes and hypodermic needles, microneedles can be nearly painless because they cannot penetrate deep enough to touch nerves and penetrate only the outermost layer of skin. Additionally, shallower penetration also reduces the chance of infection or injury. Microneedles can also facilitate the delivery of more precise doses of therapeutic agents, which enables lower doses to be used in therapy. Other advantages of microneedles for drug delivery include simplified logistics (no cold chain required), ability for patients to self-administer (d...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M37/00B29C33/00
CPCA61M37/0015A61M2037/0053B29C45/2673B29C45/2703B29L2031/7544B29L2031/756A61M2207/10B29C45/0046B29C45/263
Inventor J·德布鲁威尔H·贾斯特K·F·罗森
Owner SABIC GLOBAL TECH BV
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