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Gastroenteric motility marker capsule

A technology of gastrointestinal motility and markers, applied in preparations for in vivo tests, preparation of X-ray contrast agents, pharmaceutical formulations, etc., can solve problems such as high cost, simple packaging, increased mental burden on patients and money loss

Inactive Publication Date: 2019-12-03
安徽萍聚德医疗科技股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

With the development of medicine, patients can take orally non-toxic spherical markers that are insoluble, non-lysed, X-ray-opaque, and clearly developed in the gastrointestinal tract. To judge the function of colonic peristalsis, but most of the markers used in this method on the market are imported, and the cost is relatively high. At the same time, the existing markers have simple packaging, and patients need to come to the hospital every 24 hours after taking markers. An X-ray film will virtually increase the patient's mental burden and money loss

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] A gastrointestinal motility marker capsule, comprising a hollow capsule and a content marker, the hollow capsule is composed of gelatin, the hollow capsule is filled with a content marker, and the content marker is fully mixed by medical type I barium sulfate and medical silica gel in proportion It is made by vulcanization. According to the mass percentage, the content markers of Chinese medical type I barium sulfate account for 58%, and medical silica gel accounts for 42%.

[0014] Further, the above-mentioned medical silica gel is made of silicon dioxide, oligosiloxane, polymethyl

[0015] Hydrogen-containing siloxane is prepared, and the mass percentages of the three in the entire marker capsule are 15%, 25%, and 2%, respectively.

Embodiment 2

[0017] A gastrointestinal motility marker capsule, comprising a hollow capsule and a content marker, the hollow capsule is composed of gelatin, the hollow capsule is filled with a content marker, and the content marker is fully mixed by medical type I barium sulfate and medical silica gel in proportion It is made by vulcanization. According to the mass percentage, the content markers are 60% of Chinese medicine type I barium sulfate and 40% of medical silica gel.

[0018] Further, the above-mentioned medical silica gel is made of silicon dioxide, oligosiloxane, and polymethylhydrosiloxane, and the mass percentages of the three in the entire marker capsule are 13%, 26%, and 1%, respectively.

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Abstract

The invention discloses a gastroenteric motility marker capsule. The capsule comprises a hollow capsule and a content marker, wherein the component of the hollow capsule is gelatin, the hollow capsuleis filled with the content marker prepared from medical type-I barium sulfate and medical silica gel in proportion by sufficient mixing and vulcanization, and in percentage by mass, the medical type-I barium sulfate in the content marker accounts for 55%-60% and the medical silica gel accounts for 40%-55%. The gastroenteric motility marker capsule has the advantages of being non-toxic, non-irritating and convenient to orally take, has price advantages as compared with imported markers and is convenient to carry, two grains of capsule are taken three times at every 24 h after medicine taking,radiograph is taken in hospital after 72 h, and the marker capsule is time-saving, labor-saving and convenient.

Description

technical field [0001] The invention relates to a gastrointestinal motility marker capsule, which is applied in the technical field of diagnosis of gastrointestinal diseases. Background technique [0002] Utilizing the characteristics of barium sulfate being insoluble in water, non-absorbable, and opaque to X-rays, it can be used as a gastrointestinal contrast agent. In the past, the X-ray gastrointestinal contrast agent mainly used barium sulfate, which is a non-toxic metal salt in the gastrointestinal tract. X-ray-absorbing material powder is used as the material, supplemented with powdered agents such as flavoring agents, which are adjusted into slurry and drunk. With the development of medicine, patients can take orally non-toxic spherical markers that are insoluble, non-lysed, X-ray-opaque, and clearly developed in the gastrointestinal tract. To judge the function of colonic peristalsis, but most of the markers used in this method on the market are imported, and the co...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K49/04
CPCA61K49/0404
Inventor 方明
Owner 安徽萍聚德医疗科技股份有限公司
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