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Application of Substances for Detecting Angiopoietin-like Protein 8 Content

An angiopoietin and protein technology, applied in the field of biomedicine, can solve problems such as adverse cardiovascular event products, achieve early decision-making opportunities, make up for clinical application gaps, and achieve high accuracy effects

Active Publication Date: 2022-07-22
BEIJING ANZHEN HOSPITAL AFFILIATED TO CAPITAL MEDICAL UNIV
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Problems solved by technology

[0005] In view of this, the present invention provides an application of a substance for detecting the content of angiopoietin-like protein 8 and the application of angiopoietin-like protein 8 as a serum marker in predicting recurrent adverse cardiovascular events after percutaneous coronary intervention In order to solve the technical problems existing in the prior art

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  • Application of Substances for Detecting Angiopoietin-like Protein 8 Content
  • Application of Substances for Detecting Angiopoietin-like Protein 8 Content
  • Application of Substances for Detecting Angiopoietin-like Protein 8 Content

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Embodiment Construction

[0023] The specific embodiments of the present application will be described below with reference to the accompanying drawings.

[0024] In the present invention, unless otherwise specified, scientific and technical terms used herein have the meanings commonly understood by those skilled in the art. In addition, the reagents, materials and operation steps used herein are the reagents, materials and conventional steps widely used in the corresponding fields. Meanwhile, for a better understanding of the present invention, definitions and explanations of related terms are provided below.

[0025] Angiopoietin-like protein (ANGPTL): is a family of secreted protein factors not only related to angiogenesis, but also closely related to lipid metabolism, glucose metabolism, energy metabolism and insulin sensitivity. The ANGPTLs family contains 8 members and is a class of secreted proteins. Except for Angiopoietin-like protein 5 (ANGPTL5), which is only expressed in humans, other ANG...

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Abstract

The present application provides the use of a substance for detecting angiopoietin-like protein 8 content. The application includes the application of a substance for detecting the content of angiopoietin-like protein 8 in preparing a product for predicting or assisting in predicting recurrent adverse cardiovascular events after percutaneous coronary intervention. The application of the substance for detecting the content of angiopoietin-like protein 8 provided in this application can be applied to the prediction of adverse cardiovascular events in patients with coronary heart disease after PCI, and the prediction of PCI in patients with coronary heart disease. The risk probability of adverse cardiovascular events occurring later is high and accurate, and it can advance the decision-making time of active clinical intervention before the occurrence of adverse cardiovascular events. value.

Description

technical field [0001] This application relates to the field of biomedical technology, in particular to the application of substances for detecting the content of angiopoietin-like protein 8 and the product of angiopoietin-like protein 8 as a serum marker for predicting recurrent adverse cardiovascular events after percutaneous coronary intervention applications in . Background technique [0002] Coronary artery heart disease (CAD) is a disease of myocardial ischemia and hypoxic necrosis caused by coronary atherosclerosis-induced stenosis or obstruction of the arterial lumen. Data published in Lancet in 2013 showed that the death factor of coronary heart disease in my country jumped from the seventh in 1990 to the second in 2010. In 2010, the number of deaths from coronary heart disease reached 945,000, which is a serious threat to my country's public health. [0003] At this stage, coronary angiography (CAG) and percutaneous coronary intervention (PCI) have become importan...

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N33/68G01N33/92
CPCG01N33/6893G01N33/92G01N2800/324G01N2800/52
Inventor 秦彦文焦晓璐
Owner BEIJING ANZHEN HOSPITAL AFFILIATED TO CAPITAL MEDICAL UNIV
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