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Composition containing amomum villosum extract for prevention, alleviation, or treatment of obesity

A technology of extract and Yangchun sand, which is applied in the direction of drug combination, medical preparations containing active ingredients, food science, etc.

Inactive Publication Date: 2019-12-27
株式会社一圆生物
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, Shen et al. (SHEN Li WANG Yang JIANG Ku et al.Comparison of HPLC Fingerprints of Amomum villosum Lour., Amomurn villosum Lour.var.xanthioides T.L.Wu et Senjen and Amomum longiligulare T.L.Wu. Chinese Journal of Pharmaceutical Sciences. 2016:51(12); 1039-1043.) According to the results of RP-HPLC research, the three kinds of amomum showed a high degree of similarity in composition, but the chemical composition of Hainan sand and Yangchun sand was similar, on the contrary, green shell sand was significantly different from the first two, Detailed pharmacological and clinical efficacy comparisons are required

Method used

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  • Composition containing amomum villosum extract for prevention, alleviation, or treatment of obesity
  • Composition containing amomum villosum extract for prevention, alleviation, or treatment of obesity
  • Composition containing amomum villosum extract for prevention, alleviation, or treatment of obesity

Examples

Experimental program
Comparison scheme
Effect test

experiment example 1

[0041]Experimental example 1. The anti-obesity effect of Yangchun sand extract in the obesity model induced by high-fat diet

[0042] 1) Manufacture of Yangchun sand extract

[0043] Yang Chunsha confirmed the authenticity in the Materia Medica Classroom of the University of Traditional Chinese Medicine at Wonkwang University. This step is a step of extracting the sunflower sand with water to obtain the extract.

[0044] According to the design conditions, other solvents can be used, and according to the type of extraction solvent, the extraction temperature, extraction time, amount of solvent and residual component treatment method can be designed differently. A variety of solvents can also be used as the extraction solvent. The extractable solvents include water, ethanol, methanol, fat oil, glycerin, horse oil, ethyl acetate, acetone, butanol and isopropanol.

[0045] In the present invention, it is preferred to extract Yangchunsha with water. During the extraction proces...

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Abstract

The present invention relates to a composition containing an Amomum villosum extract as an active ingredient for prevention and alleviation of obesity. The present invention relates to a composition for prevention and alleviation of obesity, the composition being characterized in that the Amomum villosum extract is extracted with water and is contained in 100-500 mg / kg on the basis of mouse oral administration. The present invention provides a composition containing an Amomum villosum extract for prevention and alleviation of obesity, wherein the Amomum villosum extract has anti-obesity efficacy through effects of suppressing the increase in adipocytes in the liver, the size of adipocytes, and the production of neutral fats and through the in vivo inhibition of mRNA expression with respectto mechanisms of the effects.

Description

technical field [0001] The invention relates to a composition for preventing, treating or improving obesity containing the extract of Cinnamon Cinnamomi. [0002] The present invention provides a composition for preventing, treating or improving obesity containing the extract of Cinnamomum chinensis, the extract of Cinnamomum sativa inhibits the formation of fat in the liver, the size of adipocytes, and the generation of triglycerides, and inhibits the differentiation of adipocytes. The expression of gene mRNA and the inhibition of mRNA expression induced by fatty liver have the effect of preventing and improving obesity. Background technique [0003] Modern people are excessively accumulating fat in the body due to metabolic disorders caused by overnutrition and the imbalance between intake and energy consumption, and the number of obese people is increasing. [0004] This obese population is gradually increasing. In 2008, 1.5 billion adults in the world were overweight an...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/81A23L33/105
CPCA23L33/105A23L33/30A61K36/9064A61P3/06A61P1/16A61P3/04A61K36/81A23V2200/332A23V2002/00
Inventor 权康范金河林赵诚江李金山
Owner 株式会社一圆生物
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