Magnetic resonance imaging scan fixation and anesthesia integrated device for small animals and application method of integrated device

A nuclear magnetic resonance, small animal technology, applied in the direction of animal restraint equipment, applications, veterinary instruments, etc., can solve the problems of small animals suffocation, death, air leakage, etc., to reduce animal preparation time, and the fixation process is simple. Avoid the effects of suffocation

Active Publication Date: 2020-01-03
HARBIN MEDICAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Tooth rods and anesthesia hoods are made of hard plastic. Excessive force during the connection process or long-term hooking of the teeth for experiments will cause animal teeth to be injured; the anesthesia hood also has the risk of wearing away the tissues near the animal's jaw, and even causes the small animal to suffocate to death; There is a large gap between the anesthesia cover and the mouth of the animal, and there is an air leakage phenomenon, which has potential harm to the environment and the operator
In addition, when fixing the torso of small experimental animals or fixing surface coils, adhesive tape is often used to fix the small animals in the animal bed or the experimental transmitting coil. This fixing m

Method used

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  • Magnetic resonance imaging scan fixation and anesthesia integrated device for small animals and application method of integrated device
  • Magnetic resonance imaging scan fixation and anesthesia integrated device for small animals and application method of integrated device
  • Magnetic resonance imaging scan fixation and anesthesia integrated device for small animals and application method of integrated device

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0037] Example one

[0038] Such as Figure 1-2 As shown, a small animal MRI scanning fixation and anesthesia integrated device includes an anesthesia module, a head and neck fixation module, and a trunk placement fixation module.

[0039] Such as Figure 4 As shown, the anesthesia module includes a conical inflatable breathing mask. The breathing mask is connected to the air outlet of the anesthesia machine through an anesthesia tube 15. The breathing mask is provided with a first inflation port 16 through which the breathing mask is inflated. Elastic rubber bands 14 are fixed on both sides, and the breathing mask is worn on the head of the animal after two elastic rubber bands 14 are knotted.

[0040] The head and neck fixing module and the trunk placing and fixing module are detachably connected together. Such as Figure 5 As shown, the head and neck fixation module includes a ring-shaped inflatable airbag 5 with an adjustable size. The ring-shaped inflatable airbag 5 is slidably...

Example Embodiment

[0045] Example two

[0046] This embodiment is basically the same as the first embodiment, the difference lies in: Figure 1-3 As shown, both sides of the central main body support plate 1 are provided with hollow structure slots 12 along the animal torso placement direction. The slot 12 is slidably provided with a side torso support plate 2, and the side torso support plate 2 is drawn outwards. The pulling method changes the width of the fixed module on the torso, which is suitable for fixing animals of different sizes.

Example Embodiment

[0047] Example three

[0048] The method of using a small animal MRI scanning fixation and anesthesia integrated device includes the following steps:

[0049] (1) Set the water temperature of the external heating pool and the flow rate of the water pump, and connect the two ports of the plumbing silicone tube 11 to the water outlet and the water return of the external heating pool respectively;

[0050] (2) Quickly place the animal under preliminary anesthesia sleep on the central main body support plate 1, and pull out along the slot 12 according to the size of the animal to adjust the side torso support plate 2 to a suitable position;

[0051] (3) Adjust the amount of inflation of the breathing mask through the first inflation port 16, wrap the inflated breathing mask around the animal's mouth and nose, and then fit it tightly, then use the elastic rubber band 14 of the breathing mask to tie the knot and wear it on the animal. On the head, connect the breathing mask to the outlet tu...

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Abstract

The invention provides a magnetic resonance imaging scan fixation and anesthesia integrated device for small animals and an application method of the integrated device. The magnetic resonance imagingscan fixation and anesthesia integrated device includes an anesthesia module, a head and neck fixation module and a trunk placement and fixation module, the anesthesia module includes a cone-shaped inflatable breathing mask, and the breathing mask is connected with an external anesthesia tube through an anesthesia catheter; and the head and neck fixation module is detachably connected with the trunk placement and fixation module, and includes an annular inflatable airbag, the annular inflatable airbag is slidably arranged on the trunk placement and fixation module, and a head and neck fixationbelt, an upper waist fixation belt and a lower waist fixation belt are slidably arranged on the trunk placement and fixation module. The magnetic resonance imaging scan fixation and anesthesia integrated device can be adapted to animals with different sizes, put positions of the animals are not restricted, breathing patterns of the animals are conveniently controlled, the body temperature of theanimals can be kept to be stable at the physiological temperature, damage to teeth and tissues near mouths can be avoided, and death from suffocation is effectively avoided.

Description

technical field [0001] The invention relates to the technical field of nuclear magnetic resonance imaging fixation devices, in particular to a small animal nuclear magnetic resonance imaging fixation and anesthesia integrated device and its use method. Background technique [0002] The study of disease model animals can provide reference for the development process of the disease and provide potential solutions for clinical diagnosis and treatment. Magnetic resonance imaging (MRI) has become the preferred imaging detection method for disease diagnosis due to its advantages of non-invasiveness, high resolution, multi-parameter imaging, functional and molecular imaging, and more and more attention has been paid to the study of model animals. [0003] When MRI is performed on animals, gas anesthesia is generally used; animals of different sizes and different scanning parts need to use different radio frequency coils, and different imaging methods and purposes require different ...

Claims

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Application Information

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IPC IPC(8): A61B5/055A61D3/00A61D7/04
CPCA61D3/00A61D7/04A61D2003/003A61D2003/006A61B5/055
Inventor 孙夕林郑利敏王凯杨春升程永娜孙晓红程立欣
Owner HARBIN MEDICAL UNIVERSITY
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