Compound dextromethorphan hydrobromide dropping pills and preparation method thereof

A technology of dextromethorphan hydrobromide and dropping pills is applied in directions such as pill delivery, pharmaceutical formulations, and inactive medical preparations, which can solve the problems of single component, inconvenience and insignificant effect, and achieve good stability. , good oral absorption effect

Inactive Publication Date: 2020-01-24
山东禹王制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The formula of the existing dextromethorphan hydrobromide freeze-dried powder is mainly composed of hydrobromic acid\dextromethorphan, lactic acid, sorbic acid, polyethylene glycol 2000, water for injection, and the method of using this product requires injection, which is difficult for the human body to accept. Inconvenient to use
[0004] Existing andrographolide drop pills are used to treat various infections and non-infectious inflammatory diseases. The main ingredient of this kind of drop pills is andrographolide, which has a single component and the effect is not significant.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] A kind of compound dextromethorphan hydrobromide dropping pill, its composition comprises: dextromethorphan hydrobromide, andrographolide, ephedra, white flower snake skin incense, saxifrage, phoenix root, bitter almond, roasted licorice, platycodon grandiflorum, polygala , coltsfoot flower, licorice, aster, Chuan Fritillaria, loquat leaves, hundred plants, Peucedanum, Morus alba, mint, loquat leaves, polyethylene glycol A, polyethylene glycol B, glycerin, Tween, the The parts by weight of dextromethorphan hydrobromide is 1-20, the parts by weight of said andrographolide is 5-30, the parts by weight of said ephedra are 5-30, and the parts by weight of said snake skin The parts by weight of the saxifrage root are 5-30, the parts by weight of the saxifrage root are 5-30, and the parts by weight of the bitter almond are 5-30. 30. The parts by weight of the Zhi Licorice is 5-30, the parts by weight of the Platycodon grandiflora is 5-30, the parts by weight of the Polygala a...

Embodiment 2

[0021] A kind of compound dextromethorphan hydrobromide dropping pill described in embodiment 1, the parts by weight of described dextromethorphan hydrobromide is 1, the parts by weight of described andrographolide is 5, the parts by weight of described The parts by weight of ephedra are 5, the parts by weight of the described Snake Pixiang are 5, the parts by weight of the described saxifrage are 5, the parts by weight of the root of the Chinese phoenix tree are 5, the parts by weight of the described saxifrage are 5, the parts by weight of the The parts by weight of bitter almonds are 5, the parts by weight of the described Radix Glycyrrhizae are 5, the parts by weight of the described platycodon root are 5, the parts by weight of the described polygala are 5, the parts by weight of the coltsfoot flower The parts by weight are 5, the parts by weight of the described licorice are 5, the parts by weight of the described aster are 5, the parts by weight of the described Fritilla...

Embodiment 3

[0023] A kind of compound dextromethorphan hydrobromide dropping pill described in embodiment 1, the parts by weight of described dextromethorphan hydrobromide is 20, the parts by weight of described andrographolide is 30, the parts by weight of described The parts by weight of ephedra is 30, the parts by weight of the described Snakeskin is 30, the parts by weight of the described saxifrage is 30, the parts by weight of the root of the Chinese phoenix tree is 30, the parts by weight of the described The parts by weight of Bitter Almond are 30, the parts by weight of described Radix Glycyrrhizae is 30, the parts by weight of described Platycodon grandiflora is 30, the parts by weight of described Polygala is 30, the parts by weight of described coltsfoot flower The parts by weight are 30, the parts by weight of the licorice are 30, the parts by weight of the aster are 30, the parts by weight of the Fritillaria chinensis are 30, and the parts by weight of the loquat leaves are ...

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PUM

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Abstract

The invention discloses compound dextromethorphan hydrobromide dropping pills and a preparation method thereof. The product comprises 1-20 parts of dextromethorphan hydrobromide; 5-30 parts of andrographolide; 5-30 parts of herba ephedrae, 5-30 parts of long-noded pit viper; 5-30 parts of saxifraga stolonifera; 5-30 parts of firmiana root; 5-30 parts of semen armeniacae amarae; 5-30 parts of honey-fried licorice root; 5-30 parts of platycodon grandiflorum, 5-30 parts of polygala tenuifolia; 5-30 parts of flos farfarae, 5-30 parts of liquorice, 5-30 parts of aster, 5-30 parts of bulbus fritillariae cirrhosae, 5-30 parts of folium eriobotryae, 5-30 parts of radix stemonae, 5-30 parts of radix peucedani, 5-30 parts of cortex mori radicis, 5-30 parts of mint, 5-30 parts of folium eriobotryae,1-20 parts of polyethylene glycol A, 1-20 parts of glycerin, and 1-5 parts of tween. According to the compound dextromethorphan hydrobromide dropping pill, dextromethorphan hydrobromide and traditional Chinese medicine components are taken in a combined mode, the effect is more beneficial to treatment of dry cough and pharyngitis pain, and the product stability is good.

Description

technical field [0001] The invention relates to a compound dextromethorphan hydrobromide dropping pill and a preparation method thereof. Background technique [0002] The film preparation of existing dextromethorphan hydrobromide drop pill orodispersible film needs to add auxiliary materials such as polycridine potassium, film forming agent, plasticizer, disintegrating agent, humectant, increase the possible damage caused by pharmaceutical auxiliary materials Security Risk. [0003] The formula of the existing dextromethorphan hydrobromide freeze-dried powder is mainly composed of hydrobromic acid\dextromethorphan, lactic acid, sorbic acid, polyethylene glycol 2000, water for injection, and the method of using this product requires injection, which is difficult for the human body to accept. Inconvenient to use. [0004] Existing andrographolide dropping pills are used to treat multiple infections and non-infectious inflammatory diseases. The main ingredient of this kind of...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61K47/10A61K47/26A61K36/904A61P11/00A61P11/04A61P11/06A61P11/14A61P29/00A61P31/06A61K31/365A61K31/485
CPCA61K9/2031A61K31/365A61K31/485A61K36/17A61K36/185A61K36/23A61K36/28A61K36/346A61K36/484A61K36/534A61K36/605A61K36/69A61K36/73A61K36/736A61K36/748A61K36/8966A61K36/904A61P11/00A61P11/04A61P11/06A61P11/14A61P29/00A61P31/06A61K2300/00
Inventor 刘汝萃范书琴张建全马良张延秀
Owner 山东禹王制药有限公司
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