Confocal endoscope image distortion correction method based on optical fiber probe

Abstract

The invention discloses a confocal endoscope image distortion correction method based on an optical fiber probe. The method comprises the following steps: collecting a background image through a confocal endoscope based on the optical fiber probe; calculating the shape and position of the optical fiber end face in the theoretical image according to the actual image shape and position of the optical fiber end face in the background image; establishing a distortion correction function according to the relationship between the actual image shape and position of the optical fiber end face in the background image and the shape and position of the optical fiber end face in the theoretical image; and correcting the transverse distortion of the sample image acquired by the confocal endoscope basedon the optical fiber probe by using the obtained distortion correction function. According to the image distortion correction method disclosed by the invention, on the premise of not increasing the hardware complexity of the confocal endoscope, the problem of image transverse distortion of the confocal endoscope can be eliminated only according to a single picture, the change of a galvanometer motion rule can be self-adapted, the quality of the image can be improved, and the image distortion correction method has important clinical value.

Description

technical field [0001] The invention relates to the technical field of confocal endoscope imaging, in particular to a method for correcting image distortion of a confocal endoscope based on an optical fiber probe. Background technique [0002] Fiber optic probe-based confocal endoscopy is a new type of endoscope that combines laser confocal microscopy and traditional endoscopy. It can perform high-resolution histological diagnosis on living tissues, and can A certain depth of tomography plays an important role in the screening of early tumors and precancerous lesions. [0003] The structure of laser confocal endoscope based on fiber optic probe is as follows: figure 1 As shown, the laser light emitted by the laser scans the surface of the sample under the deflection of the X / Y axis scanning galvanometer. The fluorescence excited by the sample surface is transmitted to the photodetector through the optical path and converted into an electrical signal. The electrical signal...

AI Technical Summary

Problems solved by technology

The traditional method to solve the lateral distortion of confocal endoscopic imaging is divided into hardware method and software method. One of the software methods is to directly cut off the areas with serious distortion on both sides, leaving the middle area with better linearity, but the middle of the remaining image Distortion still exists

Another software method is to directly use the sinusoidal curve to represent the motion state of the galvanometer to correct the distortion caused by the movement. However, in actual use, the galvanometer deviates from the standard sinusoidal motion due to the influence of the environment, life and other reasons. At this time, if Still using sinusoidal correction will produce more distortion in the image

The hardware correction method generally uses the pixel clock to perform non-isochronous sampling, but the scanning curve of the galvanometer will change with environmental factors, and the pixel clock cannot follow this change

Moreover, the use of pixel clock will increase the hardware cost of the system

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