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Expiratory ammonia detection method and device

A detection method and detection device technology, applied in biological testing, material inspection products, etc., can solve problems such as precision VOC interference

Pending Publication Date: 2020-02-11
SUNVOU MEDICAL ELECTRONICS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0014] The purpose of the present invention is to provide a highly selective, high-precision and low-cost breath ammonia detection method, which is applied to the clinical routine detection of breath ammonia, so as to overcome the defects of existing instruments and technologies and solve the problems existing in the prior art. Sampling issues, accuracy issues, and VOC interference issues

Method used

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  • Expiratory ammonia detection method and device
  • Expiratory ammonia detection method and device
  • Expiratory ammonia detection method and device

Examples

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specific Embodiment 1

[0038] The structure of the breath ammonia detection device used in this embodiment: as figure 2 A breath ammonia detection device is shown, which is composed of an air circuit unit (100) and a total control unit (200). The air circuit unit (100) consists of an exhalation tube (110), a pressure sensor (190), a solenoid valve One (182), solenoid valve two (183), gas chamber (170), three-way solenoid valve (150), gas filter device (120), analysis pump (162), detector (130) and temperature control device (140 ), exhalation pipe (110), solenoid valve one (182), solenoid valve two (183) and air chamber (170) are connected in series, three-way solenoid valve (150), gas filter device (120), analysis pump (162 ) and the detector (130) are connected in series at both ends of the air chamber (170), the other interface of the three-way solenoid valve (150) is directly connected to the atmosphere, and the pressure sensor (190) is connected to the exhalation tube (110) and the three-way ...

specific Embodiment 2

[0051] The structure of the breath ammonia detection device used in this embodiment: as image 3A breath ammonia detection device is shown, which is composed of a gas circuit unit (100) and a general control unit (200). The air circuit unit (100) consists of an exhalation tube (110), a pressure sensor (190), a solenoid valve one (182), a solenoid valve two (183), an air chamber (170), a three-way solenoid valve (150), Gas filtering device (120), analysis pump (162), detector (130) and temperature control device (140), exhalation pipe (110), solenoid valve one (182), solenoid valve two (183) and gas chamber ( 170) connected in series, the three-way solenoid valve (150), the gas filter device (120), the analysis pump (162) and the detector (130) are connected in series at both ends of the gas chamber (170), the three-way solenoid valve (150) The other interface of the other port is directly connected to the atmosphere, and the pressure sensor (190) is connected to the pipeline ...

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Abstract

The invention provides an expiratory ammonia detection method. An acid making agent containing an alkaline reagent is taken before an expiratory ammonia test; exhaled air out of the mouth or the noseis heated or kept at constant temperature in the whole process the air enters an instrument till a sensor; and a filter is added in front of a PID detector, sensor signals of a detection sample beforeand after ammonia filtering are detected, a signal difference refers to contribution of ammonia, and the ammonia concentration value for eliminating interference is further obtained. An expiratory ammonia detection device is composed of a gas path unit and a master control unit, the gas path unit collects, measures and analyzes the exhaled air sample, and the master control unit controls the gaspath unit and collects, processes, stores and communicates information.

Description

technical field [0001] The invention relates to the field of breath detection. Background technique [0002] Clinically, changes in nitrogen and ammonia levels in the blood are associated with dysfunction of the liver, brain, kidneys, stomach, duodenum, oral cavity, and lungs. When ammonia levels in the blood are higher than those in the air, it diffuses from the blood into the lungs where it appears in exhaled air. Therefore, exhaled ammonia can be used as a biomarker for a variety of diseases and metabolic processes, thereby replacing blood testing and providing a non-invasive diagnostic method for clinical practice. In recent years, changes in breath ammonia content can be used to detect many physiological diseases, such as detection of Helicobacter pylori infection, evaluation of liver reserve function and monitoring of hemodialysis effect in renal failure. [0003] In 1997, S. Davies et al. used SIFT-MS analysis technology for the first time to quantitatively analyze ...

Claims

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Application Information

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IPC IPC(8): G01N33/48
CPCG01N33/48
Inventor 韩益苹韩杰
Owner SUNVOU MEDICAL ELECTRONICS
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