MOF-loaded procyanidine antibacterial membrane and preparation method thereof

Abstract

The invention provides an MOF-loaded procyanidine antibacterial membrane and a preparation method thereof. The MOF-loaded procyanidine antibacterial membrane is prepared from the following raw materials: a procyanidine-loaded metal-organic framework material and chitosan, and the mass of the procyanidine-loaded metal-organic framework material is 0.5%-1% of that of chitosan. The preparation methodof the MOF-loaded procyanidine antibacterial membrane comprises the following steps: dispersing the procyanidine-loaded metal-organic framework material and chitosan in a first solvent, stirring to obtain a dispersion liquid, and carrying out cast coating of the dispersion liquid to form the MOF-loaded procyanidine antibacterial membrane. According to the MOF-loaded procyanidine antibacterial membrane and the preparation method thereof, procyanidine is loaded on the metal-organic framework material which is rich in pores, large in specific surface area and stable in structures, and then the procyanidine-loaded metal-organic framework material and chitosan are subjected to membrane forming, the antibacterial activity of the MOF-loaded procyanidine antibacterial membrane is high, and the antibacterial effect lasts long.

Description

technical field [0001] The invention belongs to the technical field of antibacterial film materials, and in particular relates to a MOF-loaded proanthocyanidin antibacterial film and a preparation method thereof. Background technique [0002] With the increase of people's awareness of environmental protection, plastic products made of non-renewable petroleum-based materials that are difficult to degrade, especially materials such as plastic packaging bags, will gradually withdraw from the market. As a renewable natural biomass, chitosan has the advantages of non-toxic, renewable and degradable. It can be used to prepare films and become a substitute for plastics. Chitosan is an alkaline polysaccharide. The unique chemical structure of the amino group enables chitosan to destroy the stability of the cell membrane to produce an antibacterial effect. All have an inhibitory effect. However, although simple chitosan has antibacterial properties, the antibacterial effect is poor...

AI Technical Summary

Problems solved by technology

However, although simple chitosan has antibacterial properties, the antibacterial effect is poor. To improve the antibacterial effect of chitosan, it is necessary to properly modify chitosan to improve its antibacterial stability and high efficiency. characteristics, broaden its field of application

[0003] Chinese patent document CN1197586C discloses a proanthocyanidin compound and its preparation method. Proanthocyanidin and chitosan are physically mixed and then dried to obtain a proanthocyanidin compound. Because proanthocyanidin also has certain antibacterial properties, such as: anti-oxidation and scavenging free radicals , improve liver function damage, have inhibitory effect on cardiovascular disease, anti-cancer effect, anti-inflammatory and anti-infection effect, and protect eyesight. Bacterial performance is greatly improved, but in this technology only the compound is prepared for the preparation of health care products, it is not suitable for making it into a film, and even if this method is used to compound the two and then make a film, after film formation due to chitosan The specific surface area of ​​the film is small, and the proanthocyanidins loaded on the surface of the chitosan film can only be piled up with larger particles, and the dispersion of the proanthocyanidins is small, so that the amount of proanthocyanidins exposed on the chitosan film is small, and the activity of the proanthocyanidins is small. The antibacterial activity of the finally obtained antibacterial film is still low