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Traditional Chinese medicine composition and preparation and application thereof

A technology of traditional Chinese medicine preparations and compositions, applied in the field of traditional Chinese medicine, can solve problems such as low quality of research, recommended therapeutic drugs, and insufficient evidence-based evidence, and achieve the effect of blocking the progression of cancer, reducing morbidity and mortality, and promoting reversal

Pending Publication Date: 2020-03-06
THE FIRST AFFILIATED HOSPITAL OF GUANGZHOU UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, the treatment of chronic atrophic gastritis is mainly based on relieving traditional Chinese medicine formulas, such as antacids, gastric mucosal protective agents, etc., including the eradication of Helicobacter pylori, etc. It is difficult to fundamentally improve the gastric mucosal atrophy, intestinal metaplasia
The existing Chinese patent medicines on the market, such as Weifuchun, Moluodan and other medicines, have been reported to be effective and safe in the treatment of chronic atrophic gastritis, but the quality of the research is low and the evidence-based evidence is insufficient
At present, the expert consensus and guidelines at home and abroad have not yet recommended effective drugs for clinical treatment

Method used

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  • Traditional Chinese medicine composition and preparation and application thereof
  • Traditional Chinese medicine composition and preparation and application thereof
  • Traditional Chinese medicine composition and preparation and application thereof

Examples

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Effect test

Embodiment 1

[0039] The present embodiment is a kind of traditional Chinese medicine granule of the present invention. In parts by weight, the traditional Chinese medicine granule includes the following raw material components: 15 parts of Radix Astragali, 15 parts of Atractylodes Rhizome, 20 parts of Scutellaria barbata, 10 parts of Curcuma, 15 parts of five-finger peach and 10 parts of Citrus aurantium.

[0040] The preparation method of above-mentioned traditional Chinese medicine granule, comprises the following steps:

[0041] (1) Pretreatment of raw medicinal materials: according to the proportion of the prescription, weigh and take the medicinal materials in the prescription, and set aside; take the medicinal materials of Atractylodes Rhizoma and Curcuma Rhizoma, put them on the clean selection table respectively, spread them out, manually remove impurities, until the surface of the medicinal materials is clean, and then Use a crusher with a screen mesh diameter of 1.5 cm to crush i...

Embodiment 2

[0047] This embodiment is a Chinese medicine granule of the present invention. In parts by weight, the Chinese medicine granule includes the following raw material components: 10 parts of Atractylodes macrocephala, 10 parts of Radix Pseudostellariae, 15 parts of Poria cocos, 10 parts of Citrus aurantium, 15 parts of perilla stalks, 10 parts of Dabupi, 15 parts of barbata, 10 parts of curcuma, 15 parts of astragalus, 15 parts of five-fingered peach, 5 parts of Fritillaria and 5 parts of ground beetle.

[0048] The preparation method of above-mentioned traditional Chinese medicine granule, comprises the following steps:

[0049] (1) Pre-treatment of raw materials: According to the proportion of the prescription, get the 12 medicinal materials in the prescription, and set them aside; get the medicinal materials of Atractylodes Rhizoma, Curcuma, Fritillaria, and Wood Beetle, and put them on the clean selection table, spread them out, and manually remove impurities , until the surf...

Embodiment 3

[0055] The present embodiment is a kind of traditional Chinese medicine granule of the present invention. In parts by weight, the traditional Chinese medicine granule includes the following raw material components: 15 parts of Atractylodes macrocephala, 10 parts of Radix Pseudostellariae, 10 parts of Poria cocos, 5 parts of Citrus aurantium, 10 parts of perilla stalks, 10 parts of Dabupi, 15 parts of barbata, 10 parts of curcuma, 15 parts of astragalus, 15 parts of five-fingered peach, 5 parts of Fritillaria and 5 parts of ground beetle.

[0056] The preparation method of above-mentioned traditional Chinese medicine granule, comprises the following steps:

[0057] (1) Pre-treatment of raw materials: According to the proportion of the prescription, get the 12 medicinal materials in the prescription, and set them aside; get the medicinal materials of Atractylodes Rhizoma, Curcuma, Fritillaria, and Wood Beetle, and put them on the clean selection table, spread them out, and manual...

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Abstract

The invention relates to a traditional Chinese medicine composition and a preparation and application thereof and belongs to the technical field of traditional Chinese medicine. The traditional Chinese medicine composition comprises the following raw materials in parts by weight: 15-40 parts of rhizoma atractylodis macrocephalae, 0-30 parts of radix pseudostellariae, 0-30 parts of poria cocos, 5-15 parts of fructus aurantii, 0-30 parts of perilla stems, 0-30 parts of pericarpium arecae, 15-30 parts of herba scutellariae barbatae, 10-30 parts of rhizoma curcumae, 15-40 parts of radix astragali,15-45 parts of radix fici simplicissimae, 0-30 part of fritillary bulb and 0-20 part of ground beeltles. The traditional Chinese medicine composition provided by the invention not only can effectively relieve clinical symptoms and improve gastric mucosal lesions, but also can reverse gastric precancerous lesions and block a canceration process, so that the incidence and mortality of gastric cancer are fundamentally reduced.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition and its preparation and application, belonging to the technical field of traditional Chinese medicine. Background technique [0002] Chronic atrophic gastritis is one of the precancerous diseases of the stomach, and on the basis of it, gastric mucosal intraepithelial neoplasia becomes gastric precancerous lesions. The morbidity and mortality rate in my country is above the middle level (42.6%, 45.0%), accounting for about 1 / 2 of the world. The latest data from the National Cancer Center in 2019 shows that gastric cancer is a cancer with a high incidence in my country, and the number of new cases in 2015 ranked No. Second, the number of deaths is third. The overall situation of disease prevention and control is severe, and the task of prevention and control is arduous. Therefore, effective prevention and intervention for high-risk groups has become an important means of gastric cancer p...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P1/04A61K35/64
CPCA61K35/64A61K36/076A61K36/284A61K36/36A61K36/481A61K36/535A61K36/539A61K36/60A61K36/752A61K36/889A61K36/8966A61K36/9066A61K2236/331A61K2236/39A61K2236/51A61P1/04A61K2300/00
Inventor 刘凤斌李培武刘雨丰庄昆海潘静琳文艺
Owner THE FIRST AFFILIATED HOSPITAL OF GUANGZHOU UNIV OF CHINESE MEDICINE
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